Zinc in PDB 6x43: Mfd-Bound E.Coli Rna Polymerase Elongation Complex - II State

All present enzymatic activity of Mfd-Bound E.Coli Rna Polymerase Elongation Complex - II State:
2.7.7.6;

The structure of Mfd-Bound E.Coli Rna Polymerase Elongation Complex - II State also contains other interesting chemical elements:

Magnesium

(Mg)

2 atoms

The binding sites of Zinc atom in the Mfd-Bound E.Coli Rna Polymerase Elongation Complex - II State (pdb code 6x43). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Mfd-Bound E.Coli Rna Polymerase Elongation Complex - II State, PDB code: 6x43:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Mfd-Bound E.Coli Rna Polymerase Elongation Complex - II State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Mfd-Bound E.Coli Rna Polymerase Elongation Complex - II State within 5.0Å range: probe atom residue distance (Å) B Occ J:Zn1502 b:157.6 occ:1.00 SG J:CYS70 2.3 98.4 1.0 SG J:CYS88 2.3 100.4 1.0 SG J:CYS85 2.3 105.0 1.0 SG J:CYS72 2.3 102.5 1.0 CB J:CYS85 3.0 105.0 1.0 CB J:CYS88 3.6 100.4 1.0 CB J:CYS72 3.6 102.5 1.0 N J:CYS72 3.7 102.5 1.0 N J:CYS88 3.9 100.4 1.0 CB J:CYS70 4.0 98.4 1.0 CA J:CYS72 4.2 102.5 1.0 CB J:LYS74 4.3 102.4 1.0 CA J:CYS88 4.3 100.4 1.0 N J:LEU71 4.3 93.3 1.0 N J:GLY89 4.5 94.4 1.0 CA J:CYS85 4.5 105.0 1.0 CB J:LYS87 4.7 107.5 1.0 N J:LYS87 4.8 107.5 1.0 C J:LEU71 4.8 93.3 1.0 N J:LYS74 4.8 102.4 1.0 C J:CYS72 4.8 102.5 1.0 C J:LYS87 4.8 107.5 1.0 C J:CYS88 4.9 100.4 1.0 CB J:LEU71 4.9 93.3 1.0 CA J:LEU71 4.9 93.3 1.0 C J:CYS85 4.9 105.0 1.0 CG2 J:VAL90 5.0 88.6 1.0 N J:GLU86 5.0 107.9 1.0

Zinc binding site 2 out of 2 in the Mfd-Bound E.Coli Rna Polymerase Elongation Complex - II State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Mfd-Bound E.Coli Rna Polymerase Elongation Complex - II State within 5.0Å range: probe atom residue distance (Å) B Occ J:Zn1503 b:78.6 occ:1.00 SG J:CYS888 2.3 59.6 1.0 SG J:CYS898 2.3 55.5 1.0 SG J:CYS814 2.3 64.2 1.0 CB J:CYS895 2.4 58.1 1.0 CB J:CYS898 2.7 55.5 1.0 CB J:CYS888 2.8 59.6 1.0 CB J:CYS814 3.2 64.2 1.0 SG J:CYS895 3.3 58.1 1.0 CA J:CYS888 3.5 59.6 1.0 CA J:CYS895 3.7 58.1 1.0 N J:CYS895 3.8 58.1 1.0 CA J:CYS898 4.1 55.5 1.0 N J:ASP889 4.2 64.8 1.0 C J:CYS888 4.3 59.6 1.0 N J:CYS898 4.3 55.5 1.0 NH2 J:ARG883 4.3 60.8 1.0 CA J:CYS814 4.5 64.2 1.0 N J:CYS814 4.5 64.2 1.0 C J:CYS895 4.6 58.1 1.0 OG1 J:THR890 4.7 60.6 1.0 OG1 J:THR816 4.7 71.6 1.0 N J:CYS888 4.7 59.6 1.0 O J:CYS895 4.8 58.1 1.0

J.Y.Kang, E.Llewellyn, J.Chen, P.D.B.Olinares, J.Brewer, B.T.Chait, E.A.Campbell, S.A.Darst. Structural Basis For Transcription Complex Disruption By the Mfd Translocase. Elife V. 10 2021.
ISSN: ESSN 2050-084X
PubMed: 33480355
DOI: 10.7554/ELIFE.62117