Zinc in PDB 6wvn: Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine.

The structure of Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine., PDB code: 6wvn was solved by G.Minasov, L.Shuvalova, M.Rosas-Lemus, O.Kiryukhina, J.S.Brunzelle, K.J.F.Satchell, Center For Structural Genomics Of Infectious Diseases(Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.35 / 2.00
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	169.372, 169.372, 52.083, 90.00, 90.00, 120.00
R / Rfree (%)	16.2 / 17.8

The structure of Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine. also contains other interesting chemical elements:

Chlorine

(Cl)

15 atoms

The binding sites of Zinc atom in the Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine. (pdb code 6wvn). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine., PDB code: 6wvn:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine. within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn4401 b:53.2 occ:1.00 SG B:CYS4327 2.1 51.3 1.0 SG B:CYS4343 2.1 59.1 1.0 NE2 B:HIS4336 2.2 70.2 1.0 SG B:CYS4330 2.4 52.9 1.0 CD2 B:HIS4336 3.0 68.6 1.0 CB B:CYS4327 3.1 50.2 1.0 CB B:CYS4343 3.3 66.9 1.0 CE1 B:HIS4336 3.3 69.5 1.0 CB B:CYS4330 3.5 50.8 1.0 N B:CYS4330 3.6 54.8 1.0 CA B:CYS4330 4.0 51.4 1.0 CG B:HIS4336 4.3 70.7 1.0 ND1 B:HIS4336 4.3 68.8 1.0 CA B:CYS4343 4.4 71.7 1.0 CB B:TYR4329 4.5 60.7 1.0 CA B:CYS4327 4.5 50.9 1.0 C B:TYR4329 4.5 55.2 1.0 CB B:LYS4346 4.9 56.3 1.0 O B:CYS4327 4.9 50.8 1.0 N B:LYS4346 4.9 52.0 1.0 C B:CYS4327 4.9 52.5 1.0 CA B:TYR4329 4.9 58.0 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine. within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn4402 b:70.3 occ:1.00 SG B:CYS4370 2.3 92.5 1.0 SG B:CYS4381 2.3 67.8 1.0 SG B:CYS4383 2.3 91.1 1.0 SG B:CYS4373 2.3 70.3 1.0 CB B:CYS4370 3.3 93.0 1.0 CB B:CYS4383 3.4 91.6 1.0 CB B:CYS4373 3.4 68.3 1.0 CB B:CYS4381 3.4 70.8 1.0 N B:CYS4373 3.8 69.8 1.0 CA B:CYS4381 4.0 69.1 1.0 N B:CYS4383 4.0 87.6 1.0 CA B:CYS4373 4.2 68.9 1.0 CA B:CYS4383 4.3 93.9 1.0 N B:SER4382 4.4 74.9 1.0 C B:CYS4381 4.5 70.9 1.0 CB B:VAL4372 4.7 73.8 1.0 CA B:CYS4370 4.7 90.7 1.0 C B:VAL4372 4.9 71.5 1.0

G.Minasov, L.Shuvalova, M.Rosas-Lemus, O.Kiryukhina, J.S.Brunzelle, K.J.F.Satchell, Center For Structural Genomics Of Infectious Diseases(Csgid). Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7-Methyl-Gpppa and S-Adenosylmethionine. To Be Published.