Zinc in PDB 6wnz: Structure of A Dimer of the Sulfolobus Solfataricus Mcm N-Terminal Domain Reveals Potential Role in Mcm Ring Opening

All present enzymatic activity of Structure of A Dimer of the Sulfolobus Solfataricus Mcm N-Terminal Domain Reveals Potential Role in Mcm Ring Opening:
3.6.4.12;

The structure of Structure of A Dimer of the Sulfolobus Solfataricus Mcm N-Terminal Domain Reveals Potential Role in Mcm Ring Opening, PDB code: 6wnz was solved by M.Meagher, M.N.Spence, E.J.Enemark, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	55.227, 102.448, 128.178, 90, 90, 90
R / Rfree (%)	23.3 / 25.5

The binding sites of Zinc atom in the Structure of A Dimer of the Sulfolobus Solfataricus Mcm N-Terminal Domain Reveals Potential Role in Mcm Ring Opening (pdb code 6wnz). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of A Dimer of the Sulfolobus Solfataricus Mcm N-Terminal Domain Reveals Potential Role in Mcm Ring Opening, PDB code: 6wnz:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of A Dimer of the Sulfolobus Solfataricus Mcm N-Terminal Domain Reveals Potential Role in Mcm Ring Opening


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of A Dimer of the Sulfolobus Solfataricus Mcm N-Terminal Domain Reveals Potential Role in Mcm Ring Opening within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn301 b:58.2 occ:1.00 ND1 B:HIS144 2.1 48.4 1.0 SG B:CYS149 2.3 61.9 1.0 SG B:CYS174 2.3 61.0 1.0 SG B:CYS171 2.3 58.9 1.0 CG B:HIS144 3.0 61.5 1.0 CE1 B:HIS144 3.1 54.3 1.0 CB B:CYS171 3.3 59.4 1.0 CB B:HIS144 3.3 51.8 1.0 CB B:CYS149 3.3 62.0 1.0 CB B:CYS174 3.4 55.0 1.0 N B:CYS174 3.9 65.7 1.0 CD2 B:HIS144 4.1 62.3 1.0 NE2 B:HIS144 4.1 59.5 1.0 CA B:CYS174 4.2 66.3 1.0 CB B:LYS173 4.6 60.6 1.0 CA B:CYS171 4.7 55.3 1.0 CA B:CYS149 4.7 65.9 1.0 CA B:HIS144 4.8 52.0 1.0 C B:LYS173 4.8 62.9 1.0 O B:LYS176 4.9 66.1 1.0 C B:CYS174 5.0 61.2 1.0

Zinc binding site 2 out of 2 in the Structure of A Dimer of the Sulfolobus Solfataricus Mcm N-Terminal Domain Reveals Potential Role in Mcm Ring Opening


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of A Dimer of the Sulfolobus Solfataricus Mcm N-Terminal Domain Reveals Potential Role in Mcm Ring Opening within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:82.9 occ:1.00 ND1 A:HIS144 2.1 54.1 1.0 SG A:CYS149 2.3 89.2 1.0 SG A:CYS171 2.3 83.8 1.0 SG A:CYS174 2.3 103.3 1.0 CG A:HIS144 3.0 80.0 1.0 CE1 A:HIS144 3.1 66.5 1.0 CB A:HIS144 3.2 80.5 1.0 CB A:CYS171 3.3 79.3 1.0 CB A:CYS149 3.3 88.0 1.0 CB A:CYS174 3.4 93.6 1.0 N A:CYS174 3.9 99.9 1.0 CD2 A:HIS144 4.1 74.8 1.0 NE2 A:HIS144 4.1 66.1 1.0 CA A:CYS174 4.2 96.9 1.0 CB A:LYS173 4.6 96.5 1.0 CA A:CYS149 4.7 94.8 1.0 CA A:CYS171 4.7 76.4 1.0 CA A:HIS144 4.8 86.3 1.0 C A:LYS173 4.8 96.3 1.0 O A:LYS176 4.9 117.1 1.0 C A:CYS174 5.0 93.0 1.0

M.Meagher, M.N.Spence, E.J.Enemark. Structure of A Dimer of the Sulfolobus Solfataricus Mcm N-Terminal Domain Reveals A Potential Role in Mcm Ring Opening Acta Crystallogr.,Sect.F V. 77 177 2021.
ISSN: ESSN 2053-230X
DOI: 10.1107/S2053230X21005331