Zinc in PDB 6wmp: F. Tularensis RNAPS70-Igla Dna Complex

All present enzymatic activity of F. Tularensis RNAPS70-Igla Dna Complex:
2.7.7.6;

The structure of F. Tularensis RNAPS70-Igla Dna Complex also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the F. Tularensis RNAPS70-Igla Dna Complex (pdb code 6wmp). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the F. Tularensis RNAPS70-Igla Dna Complex, PDB code: 6wmp:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the F. Tularensis RNAPS70-Igla Dna Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of F. Tularensis RNAPS70-Igla Dna Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1702 b:91.9 occ:1.00 SG D:CYS70 2.4 73.3 1.0 SG D:CYS68 2.4 70.9 1.0 CB D:CYS83 2.9 73.5 1.0 SG D:CYS83 3.0 73.5 1.0 CB D:CYS68 3.5 70.9 1.0 CB D:CYS86 3.6 74.1 1.0 N D:CYS86 3.7 74.1 1.0 O D:CYS86 4.0 74.1 1.0 CA D:CYS86 4.1 74.1 1.0 CB D:CYS70 4.1 73.3 1.0 N D:CYS70 4.2 73.3 1.0 CA D:CYS83 4.4 73.5 1.0 C D:CYS86 4.5 74.1 1.0 CB D:LYS72 4.5 79.5 1.0 CB D:ARG85 4.5 76.4 1.0 N D:LEU69 4.6 70.0 1.0 N D:LYS72 4.7 79.5 1.0 CA D:CYS70 4.7 73.3 1.0 C D:ARG85 4.7 76.4 1.0 CA D:CYS68 4.8 70.9 1.0 N D:GLY71 4.8 76.4 1.0 N D:ARG85 4.9 76.4 1.0 C D:CYS68 4.9 70.9 1.0 SG D:CYS86 4.9 74.1 1.0 C D:CYS83 4.9 73.5 1.0 CA D:ARG85 5.0 76.4 1.0

Zinc binding site 2 out of 2 in the F. Tularensis RNAPS70-Igla Dna Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of F. Tularensis RNAPS70-Igla Dna Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1703 b:55.7 occ:1.00 SG D:CYS891 2.2 26.2 1.0 SG D:CYS894 2.3 26.6 1.0 SG D:CYS884 2.5 26.7 1.0 SG D:CYS811 2.7 28.9 1.0 CB D:CYS894 3.0 26.6 1.0 CB D:CYS884 3.3 26.7 1.0 CA D:CYS884 3.6 26.7 1.0 CB D:CYS811 3.7 28.9 1.0 CB D:CYS891 3.8 26.2 1.0 NH2 D:ARG879 3.9 28.6 1.0 CA D:CYS894 4.1 26.6 1.0 N D:LYS885 4.1 27.6 1.0 N D:CYS894 4.2 26.6 1.0 CG2 D:THR813 4.2 32.2 1.0 OG1 D:THR886 4.4 28.3 1.0 C D:CYS884 4.4 26.7 1.0 NE D:ARG879 4.5 28.6 1.0 N D:CYS811 4.6 28.9 1.0 N D:CYS891 4.6 26.2 1.0 CZ D:ARG879 4.7 28.6 1.0 CA D:CYS891 4.7 26.2 1.0 CA D:CYS811 4.7 28.9 1.0 N D:CYS884 4.8 26.7 1.0 O D:CYS891 5.0 26.2 1.0 CB D:THR813 5.0 32.2 1.0

B.A.Travis, K.M.Ramsey, S.M.Prezioso, T.Tallo, J.M.Wandzilak, A.Hsu, M.Borgnia, A.Bartesaghi, S.L.Dove, R.G.Brennan, M.A.Schumacher. Structural Basis For Virulence Activation of Francisella Tularensis. Mol.Cell 2020.
ISSN: ISSN 1097-2765
PubMed: 33217319
DOI: 10.1016/J.MOLCEL.2020.10.035