Zinc in PDB 6wmi: ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide
Protein crystallography data
The structure of ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide, PDB code: 6wmi
was solved by
R.Ren,
J.R.Horton,
X.Cheng,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
41.92 /
2.75
|
Space group
|
P 62
|
Cell size a, b, c (Å), α, β, γ (°)
|
186.257,
186.257,
46.950,
90.00,
90.00,
120.00
|
R / Rfree (%)
|
15.9 /
19.4
|
Zinc Binding Sites:
The binding sites of Zinc atom in the ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide
(pdb code 6wmi). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 10 binding sites of Zinc where determined in the
ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide, PDB code: 6wmi:
Jump to Zinc binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Zinc binding site 1 out
of 10 in 6wmi
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Zinc Binding Sites List in 6wmi
Zinc binding site 1 out
of 10 in the ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn402
b:44.5
occ:1.00
|
NE2
|
A:HIS299
|
2.0
|
54.5
|
1.0
|
NE2
|
A:HIS303
|
2.0
|
59.5
|
1.0
|
SG
|
A:CYS286
|
2.2
|
40.6
|
1.0
|
SG
|
A:CYS281
|
2.3
|
45.9
|
1.0
|
CE1
|
A:HIS299
|
2.9
|
35.0
|
1.0
|
CD2
|
A:HIS303
|
3.0
|
49.9
|
1.0
|
CD2
|
A:HIS299
|
3.0
|
45.0
|
1.0
|
CE1
|
A:HIS303
|
3.1
|
55.2
|
1.0
|
CB
|
A:CYS286
|
3.1
|
39.2
|
1.0
|
CB
|
A:CYS281
|
3.2
|
40.0
|
1.0
|
ND1
|
A:HIS299
|
4.1
|
43.9
|
1.0
|
CB
|
A:GLU283
|
4.1
|
54.9
|
1.0
|
CG
|
A:HIS303
|
4.1
|
50.9
|
1.0
|
ND1
|
A:HIS303
|
4.1
|
54.3
|
1.0
|
CG
|
A:HIS299
|
4.1
|
44.9
|
1.0
|
CA
|
A:CYS286
|
4.6
|
41.4
|
1.0
|
CA
|
A:CYS281
|
4.6
|
35.6
|
1.0
|
CG
|
A:GLU283
|
4.9
|
50.3
|
1.0
|
CD1
|
A:ILE302
|
5.0
|
49.0
|
1.0
|
|
Zinc binding site 2 out
of 10 in 6wmi
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Zinc Binding Sites List in 6wmi
Zinc binding site 2 out
of 10 in the ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn403
b:59.5
occ:1.00
|
NE2
|
A:HIS243
|
2.0
|
67.5
|
1.0
|
NE2
|
A:HIS239
|
2.1
|
71.2
|
1.0
|
SG
|
A:CYS226
|
2.2
|
58.0
|
1.0
|
SG
|
A:CYS221
|
2.4
|
54.5
|
1.0
|
CD2
|
A:HIS239
|
2.8
|
53.8
|
1.0
|
CD2
|
A:HIS243
|
2.8
|
57.5
|
1.0
|
CE1
|
A:HIS243
|
3.1
|
68.9
|
1.0
|
CB
|
A:CYS226
|
3.1
|
59.0
|
1.0
|
CE1
|
A:HIS239
|
3.2
|
50.0
|
1.0
|
CB
|
A:CYS221
|
3.3
|
51.1
|
1.0
|
CG
|
A:HIS243
|
4.0
|
62.2
|
1.0
|
CG
|
A:HIS239
|
4.0
|
49.4
|
1.0
|
ND1
|
A:HIS243
|
4.1
|
70.7
|
1.0
|
ND1
|
A:HIS239
|
4.1
|
52.8
|
1.0
|
CG2
|
A:VAL223
|
4.5
|
58.0
|
1.0
|
CA
|
A:CYS226
|
4.5
|
70.9
|
1.0
|
CB
|
A:VAL223
|
4.6
|
61.0
|
1.0
|
CA
|
A:CYS221
|
4.8
|
52.2
|
1.0
|
|
Zinc binding site 3 out
of 10 in 6wmi
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Zinc Binding Sites List in 6wmi
Zinc binding site 3 out
of 10 in the ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn404
b:73.7
occ:1.00
|
NE2
|
A:HIS333
|
2.1
|
0.3
|
1.0
|
NE2
|
A:HIS329
|
2.1
|
94.2
|
1.0
|
SG
|
A:CYS316
|
2.3
|
96.2
|
1.0
|
SG
|
A:CYS311
|
2.3
|
72.2
|
1.0
|
CD2
|
A:HIS329
|
2.9
|
77.9
|
1.0
|
CD2
|
A:HIS333
|
3.0
|
0.9
|
1.0
|
CE1
|
A:HIS333
|
3.0
|
0.8
|
1.0
|
CB
|
A:CYS316
|
3.0
|
84.3
|
1.0
|
CE1
|
A:HIS329
|
3.2
|
76.6
|
1.0
|
CB
|
A:CYS311
|
3.3
|
84.2
|
1.0
|
ND1
|
A:HIS333
|
4.0
|
1.0
|
1.0
|
CG
|
A:HIS333
|
4.1
|
0.8
|
1.0
|
CG
|
A:HIS329
|
4.1
|
75.2
|
1.0
|
ND1
|
A:HIS329
|
4.2
|
74.1
|
1.0
|
CB
|
A:ALA313
|
4.2
|
81.0
|
1.0
|
CA
|
A:CYS316
|
4.5
|
89.0
|
1.0
|
CA
|
A:CYS311
|
4.8
|
78.9
|
1.0
|
CB
|
A:ARG318
|
4.8
|
74.1
|
1.0
|
|
Zinc binding site 4 out
of 10 in 6wmi
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Zinc Binding Sites List in 6wmi
Zinc binding site 4 out
of 10 in the ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn405
b:51.9
occ:1.00
|
NE2
|
A:HIS269
|
2.0
|
54.5
|
1.0
|
NE2
|
A:HIS273
|
2.0
|
63.9
|
1.0
|
SG
|
A:CYS256
|
2.3
|
73.4
|
1.0
|
SG
|
A:CYS251
|
2.4
|
54.9
|
1.0
|
CD2
|
A:HIS269
|
2.9
|
43.8
|
1.0
|
CD2
|
A:HIS273
|
2.9
|
54.1
|
1.0
|
CE1
|
A:HIS273
|
3.1
|
56.4
|
1.0
|
CE1
|
A:HIS269
|
3.1
|
51.0
|
1.0
|
CB
|
A:CYS256
|
3.2
|
63.4
|
1.0
|
CB
|
A:CYS251
|
3.3
|
51.4
|
1.0
|
CG
|
A:HIS269
|
4.1
|
40.7
|
1.0
|
CG
|
A:HIS273
|
4.1
|
62.2
|
1.0
|
ND1
|
A:HIS269
|
4.2
|
49.3
|
1.0
|
ND1
|
A:HIS273
|
4.2
|
62.3
|
1.0
|
CB
|
A:ALA253
|
4.5
|
56.3
|
1.0
|
CA
|
A:CYS256
|
4.6
|
66.1
|
1.0
|
CA
|
A:CYS251
|
4.8
|
46.8
|
1.0
|
OG1
|
A:THR272
|
5.0
|
69.9
|
1.0
|
|
Zinc binding site 5 out
of 10 in 6wmi
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Zinc Binding Sites List in 6wmi
Zinc binding site 5 out
of 10 in the ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn406
b:0.6
occ:1.00
|
NE2
|
A:HIS361
|
2.1
|
0.6
|
1.0
|
NE2
|
A:HIS357
|
2.1
|
0.8
|
1.0
|
SG
|
A:CYS344
|
2.4
|
0.4
|
1.0
|
SG
|
A:CYS341
|
2.5
|
0.4
|
1.0
|
CD2
|
A:HIS357
|
2.7
|
0.8
|
1.0
|
CD2
|
A:HIS361
|
2.8
|
0.9
|
1.0
|
CE1
|
A:HIS361
|
3.0
|
0.7
|
1.0
|
CB
|
A:CYS344
|
3.0
|
0.7
|
1.0
|
CE1
|
A:HIS357
|
3.3
|
0.8
|
1.0
|
N
|
A:CYS344
|
3.6
|
0.1
|
1.0
|
CB
|
A:CYS341
|
3.6
|
0.0
|
1.0
|
CG
|
A:HIS361
|
3.9
|
1.0
|
1.0
|
CA
|
A:CYS344
|
3.9
|
0.5
|
1.0
|
ND1
|
A:HIS361
|
3.9
|
0.9
|
1.0
|
CG
|
A:HIS357
|
4.0
|
0.6
|
1.0
|
ND1
|
A:HIS357
|
4.2
|
0.1
|
1.0
|
CB
|
A:VAL343
|
4.4
|
0.3
|
1.0
|
C
|
A:VAL343
|
4.7
|
0.5
|
1.0
|
N
|
A:GLY345
|
4.8
|
0.4
|
1.0
|
C
|
A:CYS344
|
4.9
|
0.4
|
1.0
|
O
|
A:HIS357
|
4.9
|
0.3
|
1.0
|
CA
|
A:VAL343
|
4.9
|
0.9
|
1.0
|
|
Zinc binding site 6 out
of 10 in 6wmi
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Zinc Binding Sites List in 6wmi
Zinc binding site 6 out
of 10 in the ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Zn401
b:45.0
occ:1.00
|
NE2
|
D:HIS303
|
2.0
|
50.7
|
1.0
|
NE2
|
D:HIS299
|
2.1
|
50.8
|
1.0
|
SG
|
D:CYS286
|
2.2
|
43.4
|
1.0
|
SG
|
D:CYS281
|
2.3
|
43.6
|
1.0
|
CD2
|
D:HIS303
|
2.8
|
41.1
|
1.0
|
CE1
|
D:HIS299
|
3.0
|
40.6
|
1.0
|
CD2
|
D:HIS299
|
3.0
|
40.3
|
1.0
|
CB
|
D:CYS286
|
3.1
|
43.1
|
1.0
|
CE1
|
D:HIS303
|
3.1
|
53.3
|
1.0
|
CB
|
D:CYS281
|
3.3
|
40.9
|
1.0
|
CG
|
D:HIS303
|
4.0
|
48.6
|
1.0
|
CB
|
D:GLU283
|
4.1
|
64.9
|
1.0
|
ND1
|
D:HIS299
|
4.1
|
44.9
|
1.0
|
ND1
|
D:HIS303
|
4.1
|
51.6
|
1.0
|
CG
|
D:HIS299
|
4.2
|
38.8
|
1.0
|
CA
|
D:CYS286
|
4.5
|
57.8
|
1.0
|
CA
|
D:CYS281
|
4.8
|
40.5
|
1.0
|
CG
|
D:GLU283
|
4.8
|
67.9
|
1.0
|
CD1
|
D:ILE302
|
4.8
|
45.0
|
1.0
|
|
Zinc binding site 7 out
of 10 in 6wmi
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Zinc Binding Sites List in 6wmi
Zinc binding site 7 out
of 10 in the ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 7 of ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Zn402
b:44.9
occ:1.00
|
NE2
|
D:HIS273
|
2.0
|
47.3
|
1.0
|
NE2
|
D:HIS269
|
2.1
|
48.5
|
1.0
|
SG
|
D:CYS256
|
2.2
|
57.9
|
1.0
|
SG
|
D:CYS251
|
2.4
|
42.9
|
1.0
|
CE1
|
D:HIS269
|
3.0
|
33.9
|
1.0
|
CD2
|
D:HIS273
|
3.0
|
41.4
|
1.0
|
CE1
|
D:HIS273
|
3.0
|
45.7
|
1.0
|
CD2
|
D:HIS269
|
3.1
|
36.1
|
1.0
|
CB
|
D:CYS256
|
3.2
|
44.4
|
1.0
|
CB
|
D:CYS251
|
3.3
|
46.1
|
1.0
|
ND1
|
D:HIS269
|
4.1
|
39.0
|
1.0
|
ND1
|
D:HIS273
|
4.1
|
49.4
|
1.0
|
CG
|
D:HIS273
|
4.2
|
48.8
|
1.0
|
CG
|
D:HIS269
|
4.2
|
36.2
|
1.0
|
CB
|
D:ALA253
|
4.4
|
39.9
|
1.0
|
CA
|
D:CYS256
|
4.7
|
56.8
|
1.0
|
CA
|
D:CYS251
|
4.8
|
43.8
|
1.0
|
CG
|
D:LYS258
|
4.9
|
45.8
|
1.0
|
CB
|
D:LYS258
|
4.9
|
43.3
|
1.0
|
|
Zinc binding site 8 out
of 10 in 6wmi
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Zinc Binding Sites List in 6wmi
Zinc binding site 8 out
of 10 in the ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 8 of ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Zn403
b:77.3
occ:1.00
|
NE2
|
D:HIS329
|
2.0
|
97.3
|
1.0
|
NE2
|
D:HIS333
|
2.1
|
0.7
|
1.0
|
SG
|
D:CYS316
|
2.2
|
98.1
|
1.0
|
SG
|
D:CYS311
|
2.3
|
74.6
|
1.0
|
CD2
|
D:HIS329
|
2.8
|
74.7
|
1.0
|
CE1
|
D:HIS333
|
2.9
|
0.4
|
1.0
|
CB
|
D:CYS316
|
3.0
|
96.2
|
1.0
|
CD2
|
D:HIS333
|
3.1
|
1.0
|
1.0
|
CE1
|
D:HIS329
|
3.2
|
86.9
|
1.0
|
CB
|
D:CYS311
|
3.4
|
84.6
|
1.0
|
ND1
|
D:HIS333
|
4.0
|
0.4
|
1.0
|
CG
|
D:HIS329
|
4.0
|
72.8
|
1.0
|
CG
|
D:HIS333
|
4.1
|
0.1
|
1.0
|
ND1
|
D:HIS329
|
4.2
|
84.1
|
1.0
|
CA
|
D:CYS316
|
4.5
|
95.6
|
1.0
|
CB
|
D:ALA313
|
4.6
|
99.7
|
1.0
|
CA
|
D:CYS311
|
4.8
|
89.6
|
1.0
|
CB
|
D:ARG318
|
4.8
|
66.1
|
1.0
|
|
Zinc binding site 9 out
of 10 in 6wmi
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Zinc Binding Sites List in 6wmi
Zinc binding site 9 out
of 10 in the ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 9 of ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Zn404
b:0.0
occ:1.00
|
NE2
|
D:HIS361
|
2.1
|
0.7
|
1.0
|
NE2
|
D:HIS357
|
2.1
|
0.2
|
1.0
|
CD2
|
D:HIS361
|
2.3
|
0.8
|
1.0
|
SG
|
D:CYS344
|
2.4
|
0.7
|
1.0
|
SG
|
D:CYS341
|
2.5
|
0.5
|
1.0
|
CE1
|
D:HIS357
|
2.9
|
0.4
|
1.0
|
CD2
|
D:HIS357
|
3.0
|
0.2
|
1.0
|
CB
|
D:CYS344
|
3.1
|
0.2
|
1.0
|
CE1
|
D:HIS361
|
3.3
|
0.2
|
1.0
|
CG
|
D:HIS361
|
3.6
|
0.4
|
1.0
|
CB
|
D:CYS341
|
3.8
|
0.9
|
1.0
|
N
|
D:CYS344
|
3.9
|
0.8
|
1.0
|
ND1
|
D:HIS357
|
3.9
|
0.2
|
1.0
|
CG
|
D:HIS357
|
4.0
|
0.3
|
1.0
|
ND1
|
D:HIS361
|
4.1
|
0.1
|
1.0
|
CA
|
D:CYS344
|
4.1
|
0.2
|
1.0
|
CB
|
D:VAL343
|
4.6
|
0.8
|
1.0
|
CB
|
D:HIS361
|
4.8
|
0.0
|
1.0
|
CG
|
D:MET358
|
4.8
|
0.7
|
1.0
|
C
|
D:VAL343
|
4.9
|
0.2
|
1.0
|
|
Zinc binding site 10 out
of 10 in 6wmi
Go back to
Zinc Binding Sites List in 6wmi
Zinc binding site 10 out
of 10 in the ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 10 of ZNF410 Zinc Fingers 1-5 with 17 Mer Blunt Dna Oligonucleotide within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Zn405
b:59.5
occ:1.00
|
NE2
|
D:HIS243
|
2.1
|
58.4
|
1.0
|
NE2
|
D:HIS239
|
2.1
|
63.7
|
1.0
|
SG
|
D:CYS226
|
2.3
|
59.7
|
1.0
|
SG
|
D:CYS221
|
2.3
|
63.5
|
1.0
|
CD2
|
D:HIS239
|
3.0
|
46.5
|
1.0
|
CD2
|
D:HIS243
|
3.0
|
54.2
|
1.0
|
CE1
|
D:HIS243
|
3.0
|
59.6
|
1.0
|
CE1
|
D:HIS239
|
3.0
|
49.8
|
1.0
|
CB
|
D:CYS226
|
3.2
|
64.7
|
1.0
|
CB
|
D:CYS221
|
3.4
|
59.5
|
1.0
|
CG
|
D:HIS239
|
4.1
|
40.3
|
1.0
|
ND1
|
D:HIS243
|
4.1
|
51.9
|
1.0
|
ND1
|
D:HIS239
|
4.1
|
45.6
|
1.0
|
CG
|
D:HIS243
|
4.1
|
50.7
|
1.0
|
CB
|
D:VAL223
|
4.3
|
50.1
|
1.0
|
CG2
|
D:VAL223
|
4.5
|
43.5
|
1.0
|
CA
|
D:CYS226
|
4.7
|
68.3
|
1.0
|
CA
|
D:CYS221
|
4.8
|
51.1
|
1.0
|
|
Reference:
R.Ren,
J.R.Horton,
X.Cheng.
Zinc Finger To Be Published.
Page generated: Tue Oct 29 10:13:43 2024
|