Zinc in PDB 6wlh: Rna Complex of WT1 Zinc Finger Transcription Factor

The binding sites of Zinc atom in the Rna Complex of WT1 Zinc Finger Transcription Factor (pdb code 6wlh). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Rna Complex of WT1 Zinc Finger Transcription Factor, PDB code: 6wlh:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Rna Complex of WT1 Zinc Finger Transcription Factor


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Rna Complex of WT1 Zinc Finger Transcription Factor within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:10.0 occ:1.00 NE2 A:HIS26 2.1 10.0 1.0 NE2 A:HIS30 2.1 10.0 1.0 SG A:CYS13 2.3 10.0 1.0 SG A:CYS8 2.3 10.0 1.0 HZ1 A:LYS29 2.4 10.0 1.0 HZ2 A:LYS29 2.8 10.0 1.0 HZ3 A:LYS29 2.8 10.0 1.0 NZ A:LYS29 2.9 10.0 1.0 CD2 A:HIS26 3.0 10.0 1.0 CD2 A:HIS30 3.1 10.0 1.0 HB3 A:CYS13 3.1 10.0 1.0 CE1 A:HIS30 3.1 10.0 1.0 CE1 A:HIS26 3.2 10.0 1.0 HD2 A:HIS26 3.2 10.0 1.0 CB A:CYS13 3.2 10.0 1.0 HD2 A:HIS30 3.3 10.0 1.0 HB2 A:CYS8 3.4 10.0 1.0 CB A:CYS8 3.4 10.0 1.0 HE1 A:HIS30 3.4 10.0 1.0 HB3 A:TYR10 3.4 10.0 1.0 HE1 A:HIS26 3.5 10.0 1.0 HB3 A:CYS8 3.6 10.0 1.0 HB2 A:CYS13 3.6 10.0 1.0 H A:ASN14 4.0 10.0 1.0 H A:LYS15 4.1 10.0 1.0 HB2 A:TYR10 4.2 10.0 1.0 CG A:HIS26 4.2 10.0 1.0 CG A:HIS30 4.2 10.0 1.0 ND1 A:HIS30 4.2 10.0 1.0 ND1 A:HIS26 4.3 10.0 1.0 CB A:TYR10 4.3 10.0 1.0 H A:TYR10 4.3 10.0 1.0 CE A:LYS29 4.4 10.0 1.0 HG2 A:LYS29 4.5 10.0 1.0 N A:ASN14 4.5 10.0 1.0 HB3 A:LYS15 4.5 10.0 1.0 CA A:CYS13 4.6 10.0 1.0 HD3 A:LYS29 4.7 10.0 1.0 CA A:CYS8 4.8 10.0 1.0 HE3 A:LYS29 4.8 10.0 1.0 C A:CYS13 4.9 10.0 1.0 HA A:SER27 4.9 10.0 1.0 HA A:CYS8 5.0 10.0 1.0 CD A:LYS29 5.0 10.0 1.0 HE2 A:LYS29 5.0 10.0 1.0

Zinc binding site 2 out of 4 in the Rna Complex of WT1 Zinc Finger Transcription Factor


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Rna Complex of WT1 Zinc Finger Transcription Factor within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn202 b:10.0 occ:1.00 NE2 A:HIS56 2.1 10.0 1.0 NE2 A:HIS60 2.1 10.0 1.0 SG A:CYS43 2.3 10.0 1.0 SG A:CYS38 2.3 10.0 1.0 HH12 A:ARG59 2.3 10.0 1.0 CD2 A:HIS56 2.8 10.0 1.0 HD2 A:HIS56 2.8 10.0 1.0 CD2 A:HIS60 3.0 10.0 1.0 CB A:CYS38 3.0 10.0 1.0 CB A:CYS43 3.1 10.0 1.0 HB3 A:CYS38 3.1 10.0 1.0 HB2 A:CYS38 3.1 10.0 1.0 HB2 A:CYS43 3.1 10.0 1.0 HB3 A:CYS43 3.1 10.0 1.0 CE1 A:HIS60 3.2 10.0 1.0 HD2 A:HIS60 3.2 10.0 1.0 NH1 A:ARG59 3.3 10.0 1.0 CE1 A:HIS56 3.3 10.0 1.0 HE1 A:HIS60 3.4 10.0 1.0 HE A:ARG45 3.5 10.0 1.0 HH11 A:ARG59 3.6 10.0 1.0 HB3 A:PHE40 3.7 10.0 1.0 HE1 A:HIS56 3.7 10.0 1.0 HA A:GLN57 3.8 10.0 1.0 HH12 A:ARG45 3.8 10.0 1.0 HE A:ARG59 3.8 10.0 1.0 HB2 A:PHE40 4.1 10.0 1.0 CG A:HIS56 4.1 10.0 1.0 HB2 A:ARG45 4.2 10.0 1.0 CG A:HIS60 4.2 10.0 1.0 ND1 A:HIS60 4.3 10.0 1.0 HZ A:PHE47 4.3 10.0 1.0 ND1 A:HIS56 4.3 10.0 1.0 HE21 A:GLN57 4.3 10.0 1.0 CZ A:ARG59 4.3 10.0 1.0 CB A:PHE40 4.4 10.0 1.0 NE A:ARG45 4.4 10.0 1.0 NE A:ARG59 4.5 10.0 1.0 CA A:CYS38 4.5 10.0 1.0 CA A:CYS43 4.6 10.0 1.0 HG3 A:GLN57 4.6 10.0 1.0 NH1 A:ARG45 4.7 10.0 1.0 H A:PHE40 4.7 10.0 1.0 O A:HIS56 4.8 10.0 1.0 HD2 A:PHE40 4.8 10.0 1.0 HA A:CYS38 4.8 10.0 1.0 H A:ARG45 4.8 10.0 1.0 CA A:GLN57 4.8 10.0 1.0 HA A:CYS43 4.8 10.0 1.0 HB3 A:ARG59 5.0 10.0 1.0

Zinc binding site 3 out of 4 in the Rna Complex of WT1 Zinc Finger Transcription Factor


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Rna Complex of WT1 Zinc Finger Transcription Factor within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn203 b:10.0 occ:1.00 NE2 A:HIS84 2.0 10.0 1.0 NE2 A:HIS88 2.1 10.0 1.0 SG A:CYS68 2.3 10.0 1.0 SG A:CYS71 2.3 10.0 1.0 HE1 A:HIS84 2.5 10.0 1.0 CE1 A:HIS84 2.6 10.0 1.0 H A:CYS71 2.7 10.0 1.0 CD2 A:HIS88 2.9 10.0 1.0 HB2 A:CYS68 3.0 10.0 1.0 HD2 A:HIS88 3.1 10.0 1.0 CB A:CYS68 3.2 10.0 1.0 CE1 A:HIS88 3.2 10.0 1.0 HB A:THR70 3.2 10.0 1.0 HB3 A:CYS71 3.3 10.0 1.0 CB A:CYS71 3.4 10.0 1.0 CD2 A:HIS84 3.4 10.0 1.0 HB3 A:CYS68 3.4 10.0 1.0 N A:CYS71 3.5 10.0 1.0 HE1 A:HIS88 3.5 10.0 1.0 H A:GLN72 3.8 10.0 1.0 ND1 A:HIS84 3.9 10.0 1.0 HB2 A:ARG73 3.9 10.0 1.0 H A:ARG73 3.9 10.0 1.0 HD2 A:HIS84 3.9 10.0 1.0 CA A:CYS71 3.9 10.0 1.0 H A:THR70 4.0 10.0 1.0 CG A:HIS88 4.2 10.0 1.0 CG A:HIS84 4.2 10.0 1.0 ND1 A:HIS88 4.3 10.0 1.0 CB A:THR70 4.3 10.0 1.0 HB2 A:CYS71 4.3 10.0 1.0 N A:GLN72 4.4 10.0 1.0 C A:THR70 4.5 10.0 1.0 HA A:THR85 4.5 10.0 1.0 C A:CYS71 4.5 10.0 1.0 CA A:CYS68 4.6 10.0 1.0 HD1 A:HIS84 4.7 10.0 1.0 HG1 A:THR70 4.7 10.0 1.0 HD2 A:ARG73 4.7 10.0 1.0 N A:THR70 4.7 10.0 1.0 H A:LYS69 4.7 10.0 1.0 CA A:THR70 4.7 10.0 1.0 HA A:CYS68 4.8 10.0 1.0 N A:ARG73 4.8 10.0 1.0 HA A:CYS71 4.9 10.0 1.0 CB A:ARG73 4.9 10.0 1.0 HG22 A:THR70 5.0 10.0 1.0 HE2 A:PHE75 5.0 10.0 1.0

Zinc binding site 4 out of 4 in the Rna Complex of WT1 Zinc Finger Transcription Factor


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Rna Complex of WT1 Zinc Finger Transcription Factor within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn204 b:10.0 occ:1.00 NE2 A:HIS114 2.1 10.0 1.0 NE2 A:HIS118 2.1 10.0 1.0 SG A:CYS96 2.3 10.0 1.0 SG A:CYS101 2.3 10.0 1.0 CD2 A:HIS114 2.8 10.0 1.0 CD2 A:HIS118 2.9 10.0 1.0 HB3 A:CYS101 2.9 10.0 1.0 HD2 A:HIS114 2.9 10.0 1.0 CB A:CYS101 2.9 10.0 1.0 HD2 A:HIS118 2.9 10.0 1.0 HB2 A:CYS101 2.9 10.0 1.0 CE1 A:HIS118 3.3 10.0 1.0 CE1 A:HIS114 3.3 10.0 1.0 CB A:CYS96 3.5 10.0 1.0 HB2 A:CYS96 3.5 10.0 1.0 HB2 A:TRP98 3.6 10.0 1.0 HE1 A:HIS118 3.7 10.0 1.0 HE1 A:HIS114 3.7 10.0 1.0 HB3 A:CYS96 3.8 10.0 1.0 HD3 A:LYS103 3.9 10.0 1.0 HB2 A:LYS103 4.0 10.0 1.0 CG A:HIS114 4.1 10.0 1.0 CG A:HIS118 4.1 10.0 1.0 ND1 A:HIS114 4.3 10.0 1.0 ND1 A:HIS118 4.3 10.0 1.0 CA A:CYS101 4.4 10.0 1.0 H A:LYS103 4.5 10.0 1.0 HZ A:PHE105 4.5 10.0 1.0 H A:TRP98 4.6 10.0 1.0 CB A:TRP98 4.7 10.0 1.0 HA A:CYS101 4.8 10.0 1.0 CA A:CYS96 4.8 10.0 1.0 HA A:CYS96 4.9 10.0 1.0 CD A:LYS103 4.9 10.0 1.0 HD1 A:TRP98 4.9 10.0 1.0 H A:GLN102 5.0 10.0 1.0

T.Nishikawa, J.M.Wojciak, H.J.Dyson, P.E.Wright. Rna Binding By the Kts Splice Variants of Wilms' Tumor Suppressor Protein WT1. Biochemistry V. 59 3889 2020.
ISSN: ISSN 0006-2960
PubMed: 32955251
DOI: 10.1021/ACS.BIOCHEM.0C00602