Zinc in PDB 6wjn: Sd-Like State of Human 26S Proteasome with Non-Cleavable M1-Linked Hexaubiquitin and E3 Ubiquitin Ligase E6AP/UBE3A

All present enzymatic activity of Sd-Like State of Human 26S Proteasome with Non-Cleavable M1-Linked Hexaubiquitin and E3 Ubiquitin Ligase E6AP/UBE3A:
3.4.25.1;

The binding sites of Zinc atom in the Sd-Like State of Human 26S Proteasome with Non-Cleavable M1-Linked Hexaubiquitin and E3 Ubiquitin Ligase E6AP/UBE3A (pdb code 6wjn). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Sd-Like State of Human 26S Proteasome with Non-Cleavable M1-Linked Hexaubiquitin and E3 Ubiquitin Ligase E6AP/UBE3A, PDB code: 6wjn:

Zinc binding site 1 out of 1 in the Sd-Like State of Human 26S Proteasome with Non-Cleavable M1-Linked Hexaubiquitin and E3 Ubiquitin Ligase E6AP/UBE3A


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Sd-Like State of Human 26S Proteasome with Non-Cleavable M1-Linked Hexaubiquitin and E3 Ubiquitin Ligase E6AP/UBE3A within 5.0Å range: probe atom residue distance (Å) B Occ c:Zn401 b:0.7 occ:1.00 NE2 c:HIS113 2.0 0.7 1.0 O c:SER114 2.1 1.0 1.0 CD2 c:HIS115 2.2 0.8 1.0 CB c:GLU52 2.3 0.4 1.0 NE2 c:HIS115 2.7 0.8 1.0 CD2 c:HIS113 2.8 0.7 1.0 CE1 c:HIS113 2.8 0.7 1.0 C c:SER114 3.3 1.0 1.0 CG c:HIS115 3.3 0.8 1.0 CA c:GLU52 3.6 0.4 1.0 O c:VAL53 3.7 0.4 1.0 ND1 c:HIS113 3.8 0.7 1.0 CG c:HIS113 3.8 0.7 1.0 CE1 c:HIS115 3.8 0.8 1.0 CA c:HIS115 3.9 0.8 1.0 C c:GLU52 3.9 0.4 1.0 N c:VAL53 3.9 0.4 1.0 N c:HIS115 4.0 0.8 1.0 ND1 c:HIS115 4.1 0.8 1.0 CB c:HIS115 4.1 0.8 1.0 N c:SER114 4.3 1.0 1.0 CA c:SER114 4.4 1.0 1.0 C c:VAL53 4.5 0.4 1.0 O c:GLU52 4.7 0.4 1.0 N c:GLU52 4.7 0.4 1.0 CA c:VAL53 4.9 0.4 1.0 CB c:VAL82 4.9 0.3 1.0

X.Chen, Z.Dorris, D.Shi, R.K.Huang, H.Khant, T.Fox, N.De Val, D.Williams, P.Zhang, K.J.Walters. Cryo-Em Reveals Unanchored M1-Ubiquitin Chain Binding at HRPN11 of the 26S Proteasome. Structure V. 28 1206 2020.
ISSN: ISSN 0969-2126
PubMed: 32783951
DOI: 10.1016/J.STR.2020.07.011