Zinc in PDB 6wis: Copper Resistance Protein Copg- Form 1

The structure of Copper Resistance Protein Copg- Form 1, PDB code: 6wis was solved by A.C.Hausrath, A.Ly, M.M.Mcevoy, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.06 / 2.00
Space group	P 61
Cell size a, b, c (Å), α, β, γ (°)	86.130, 86.130, 58.560, 90.00, 90.00, 120.00
R / Rfree (%)	17.2 / 22

The structure of Copper Resistance Protein Copg- Form 1 also contains other interesting chemical elements:

Copper

(Cu)

8 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 15;

Binding sites:

The binding sites of Zinc atom in the Copper Resistance Protein Copg- Form 1 (pdb code 6wis). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 15 binding sites of Zinc where determined in the Copper Resistance Protein Copg- Form 1, PDB code: 6wis:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Zinc binding site 1 out of 15 in the Copper Resistance Protein Copg- Form 1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Copper Resistance Protein Copg- Form 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn208 b:31.0 occ:1.00 NE2 A:HIS22 2.0 35.7 1.0 OE2 A:GLU98 2.3 35.8 1.0 OD1 A:ASP18 2.3 43.2 1.0 OD2 A:ASP18 2.3 46.0 1.0 CG A:ASP18 2.6 34.2 1.0 O A:HOH333 2.8 39.9 1.0 CD2 A:HIS22 3.0 29.6 1.0 CD A:GLU98 3.0 43.1 1.0 OE1 A:GLU98 3.0 32.9 1.0 CE1 A:HIS22 3.0 37.7 1.0 O B:HOH306 3.8 42.7 1.0 CG A:HIS22 4.1 32.5 1.0 ND1 A:HIS22 4.1 39.0 1.0 CB A:ASP18 4.1 28.4 1.0 CA A:GLY96 4.2 23.8 1.0 N A:GLY96 4.3 27.0 1.0 CG A:GLU98 4.4 34.3 1.0 O A:ASP18 4.6 24.1 1.0 CA B:GLY14 4.7 29.4 1.0 NZ B:LYS17 4.8 45.2 1.0 C A:ASP18 4.9 25.6 1.0 O3 A:GOL207 4.9 46.3 1.0 CA A:ASP18 4.9 27.8 1.0 C A:GLY96 4.9 27.4 1.0

Zinc binding site 2 out of 15 in the Copper Resistance Protein Copg- Form 1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Copper Resistance Protein Copg- Form 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn209 b:40.7 occ:1.00 ND1 A:HIS8 2.1 37.5 1.0 NE2 A:HIS33 2.2 38.3 1.0 OE1 A:GLU35 2.3 38.2 1.0 CE1 A:HIS8 3.1 38.7 1.0 CD2 A:HIS33 3.1 40.7 1.0 CG A:HIS8 3.1 32.8 1.0 CE1 A:HIS33 3.2 39.6 1.0 CD A:GLU35 3.2 37.8 1.0 CB A:HIS8 3.4 26.4 1.0 OE2 A:GLU35 3.5 37.4 1.0 CG2 A:VAL41 4.0 29.5 1.0 NE2 A:HIS8 4.2 39.8 1.0 CD2 A:HIS8 4.2 39.1 1.0 CG A:HIS33 4.2 38.0 1.0 ND1 A:HIS33 4.3 35.7 1.0 CA A:HIS8 4.3 26.3 1.0 CG A:GLU35 4.4 35.1 1.0 CB A:GLU35 4.5 29.2 1.0 CA A:GLU35 4.6 38.2 1.0

Zinc binding site 3 out of 15 in the Copper Resistance Protein Copg- Form 1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Copper Resistance Protein Copg- Form 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn210 b:66.2 occ:1.00 OD1 A:ASP32 2.4 41.6 1.0 OD2 A:ASP32 2.8 38.6 1.0 CG A:ASP32 3.0 40.2 1.0 O A:HOH342 3.0 50.6 1.0 ZN A:ZN213 3.4 79.1 1.0 O A:HOH334 4.3 41.0 1.0 CB A:ASP32 4.5 33.3 1.0 NH2 A:ARG9 4.5 32.1 1.0 O A:ASP32 4.7 38.1 1.0 ZN A:ZN211 4.9 90.9 1.0

Zinc binding site 4 out of 15 in the Copper Resistance Protein Copg- Form 1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Copper Resistance Protein Copg- Form 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn211 b:90.9 occ:1.00 OE2 A:GLU24 2.5 46.1 1.0 OE1 A:GLU24 2.8 41.1 1.0 CD A:GLU24 3.0 37.8 1.0 ZN A:ZN213 3.1 79.1 1.0 O A:HOH342 3.3 50.6 1.0 O A:HOH315 4.2 41.2 1.0 CG2 A:ILE20 4.4 29.6 1.0 CG A:GLU24 4.5 31.7 1.0 ZN A:ZN210 4.9 66.2 1.0

Zinc binding site 5 out of 15 in the Copper Resistance Protein Copg- Form 1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Copper Resistance Protein Copg- Form 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn212 b:84.8 occ:1.00 OE2 A:GLU78 2.2 61.4 1.0 OE1 A:GLU78 2.6 55.5 1.0 CD A:GLU78 2.7 54.2 1.0 CG A:GLU78 4.2 47.6 1.0

Zinc binding site 6 out of 15 in the Copper Resistance Protein Copg- Form 1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Copper Resistance Protein Copg- Form 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn213 b:79.1 occ:1.00 ZN A:ZN211 3.1 90.9 1.0 ZN A:ZN210 3.4 66.2 1.0 OE2 A:GLU24 3.9 46.1 1.0 OD1 A:ASP32 4.0 41.6 1.0 O A:HOH342 4.2 50.6 1.0 O A:VAL30 4.2 36.5 1.0 O A:HOH334 4.4 41.0 1.0

Zinc binding site 7 out of 15 in the Copper Resistance Protein Copg- Form 1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 7 of Copper Resistance Protein Copg- Form 1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn208 b:31.3 occ:1.00 NE2 B:HIS22 2.1 41.6 1.0 OD2 B:ASP18 2.1 36.2 1.0 OE2 B:GLU98 2.1 35.2 1.0 ZN B:ZN215 2.3 70.8 1.0 OD1 B:ASP18 2.6 48.3 1.0 CG B:ASP18 2.7 36.6 1.0 CD B:GLU98 2.9 39.9 1.0 OE1 B:GLU98 3.0 34.1 1.0 CD2 B:HIS22 3.0 33.2 1.0 CE1 B:HIS22 3.1 47.9 1.0 O B:HOH321 3.6 43.8 1.0 CB B:ASP18 4.2 24.6 1.0 ND1 B:HIS22 4.2 40.8 1.0 CG B:HIS22 4.2 35.9 1.0 CG B:GLU98 4.3 33.6 1.0 CA B:GLY96 4.4 24.1 1.0 N B:GLY96 4.4 25.8 1.0 CA A:GLY14 4.6 29.7 1.0 O B:ASP18 4.7 24.7 1.0 C B:ASP18 5.0 29.8 1.0

Zinc binding site 8 out of 15 in the Copper Resistance Protein Copg- Form 1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 8 of Copper Resistance Protein Copg- Form 1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn209 b:47.6 occ:1.00 NE2 B:HIS33 2.1 43.1 1.0 ND1 B:HIS8 2.1 40.2 1.0 OE1 B:GLU35 2.3 45.9 1.0 CE1 B:HIS8 3.0 43.4 1.0 CE1 B:HIS33 3.0 43.4 1.0 CD2 B:HIS33 3.1 42.0 1.0 CG B:HIS8 3.2 32.9 1.0 CD B:GLU35 3.2 40.5 1.0 OE2 B:GLU35 3.5 40.8 1.0 CB B:HIS8 3.6 31.0 1.0 CG2 B:VAL41 3.9 35.6 1.0 NE2 B:HIS8 4.1 44.2 1.0 ND1 B:HIS33 4.2 48.6 1.0 CG B:HIS33 4.2 47.2 1.0 CD2 B:HIS8 4.2 36.7 1.0 CA B:HIS8 4.5 32.9 1.0 CG B:GLU35 4.5 37.7 1.0 CB B:GLU35 4.6 38.3 1.0 CA B:GLU35 4.7 38.2 1.0

Zinc binding site 9 out of 15 in the Copper Resistance Protein Copg- Form 1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 9 of Copper Resistance Protein Copg- Form 1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn210 b:74.4 occ:1.00 OD1 B:ASP32 2.3 41.9 1.0 O B:HOH345 2.4 51.1 1.0 OD2 B:ASP32 3.0 37.1 1.0 CG B:ASP32 3.0 38.8 1.0 ZN B:ZN216 3.1 89.5 1.0 CB B:ASP32 4.4 35.5 1.0 NH2 B:ARG9 4.5 32.3 1.0 O B:ASP32 4.5 32.6 1.0 O B:HOH342 4.5 53.4 1.0 N B:ASP32 5.0 32.3 1.0

Zinc binding site 10 out of 15 in the Copper Resistance Protein Copg- Form 1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 10 of Copper Resistance Protein Copg- Form 1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn211 b:96.1 occ:1.00 OE1 B:GLU24 2.8 44.1 1.0 OE2 B:GLU24 2.9 46.5 1.0 CD B:GLU24 3.2 47.0 1.0 ZN B:ZN216 3.5 89.5 1.0 CD B:LYS21 4.2 49.7 1.0 CE B:LYS21 4.2 55.5 1.0 CG B:GLU24 4.7 34.4 1.0 CG2 B:ILE20 4.8 32.1 1.0

A.C.Hausrath, N.A.Ramirez, A.T.Ly, M.M.Mcevoy. The Bacterial Copper-Resistance Protein Copg Contains A Cysteine-Bridged Tetranuclear Copper Cluster J.Biol.Chem. 2020.
ISSN: ESSN 1083-351X