Zinc in PDB 6wi7: RING1B-BMI1 Fusion in Closed Conformation

Protein crystallography data

The structure of RING1B-BMI1 Fusion in Closed Conformation, PDB code: 6wi7 was solved by H.J.Cho, T.Cierpicki, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 36.52 / 1.70
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 49.311, 54.353, 82.266, 90, 90, 90
R / Rfree (%) 16.5 / 19.6

Zinc Binding Sites:

The binding sites of Zinc atom in the RING1B-BMI1 Fusion in Closed Conformation (pdb code 6wi7). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the RING1B-BMI1 Fusion in Closed Conformation, PDB code: 6wi7:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in 6wi7

Go back to Zinc Binding Sites List in 6wi7
Zinc binding site 1 out of 4 in the RING1B-BMI1 Fusion in Closed Conformation


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of RING1B-BMI1 Fusion in Closed Conformation within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1201

b:16.2
occ:1.00
SG A:CYS1021 2.3 16.4 1.0
SG A:CYS1042 2.3 17.3 1.0
SG A:CYS1039 2.4 16.3 1.0
SG A:CYS1018 2.4 14.4 1.0
CB A:CYS1018 3.0 11.9 1.0
CB A:CYS1039 3.1 14.2 1.0
CB A:CYS1021 3.3 16.6 1.0
CB A:CYS1042 3.4 15.1 1.0
N A:CYS1021 3.8 18.8 1.0
N A:CYS1039 3.8 13.3 1.0
CA A:CYS1039 4.1 13.8 1.0
CA A:CYS1021 4.1 16.9 1.0
NH1 A:ARG26 4.3 16.8 1.0
CA A:CYS1018 4.4 12.1 1.0
O A:HOH1372 4.5 15.4 1.0
CB A:LEU1020 4.7 14.3 1.0
CA A:CYS1042 4.8 17.0 1.0
C A:LEU1020 4.8 20.2 1.0
O A:CYS1018 4.8 15.9 1.0
C A:CYS1018 4.8 13.8 1.0
O A:HOH1500 4.9 29.5 1.0

Zinc binding site 2 out of 4 in 6wi7

Go back to Zinc Binding Sites List in 6wi7
Zinc binding site 2 out of 4 in the RING1B-BMI1 Fusion in Closed Conformation


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of RING1B-BMI1 Fusion in Closed Conformation within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1202

b:15.8
occ:1.00
ND1 A:HIS1036 2.0 17.6 1.0
SG A:CYS1053 2.3 15.0 1.0
SG A:CYS1034 2.3 18.4 1.0
SG A:CYS1056 2.4 16.1 1.0
CE1 A:HIS1036 3.0 20.6 1.0
CG A:HIS1036 3.1 23.8 1.0
CB A:CYS1053 3.1 13.6 1.0
CB A:CYS1034 3.2 18.2 1.0
CB A:CYS1056 3.4 17.9 1.0
CB A:HIS1036 3.5 19.4 1.0
N A:CYS1056 3.8 13.8 1.0
NE2 A:HIS1036 4.1 24.9 1.0
CA A:CYS1056 4.2 18.6 1.0
CD2 A:HIS1036 4.2 22.8 1.0
O A:HOH1477 4.4 65.8 1.0
CA A:CYS1034 4.5 15.2 1.0
CA A:CYS1053 4.6 14.6 1.0
N A:HIS1036 4.6 14.6 1.0
O A:HOH1568 4.6 27.6 1.0
CG1 A:VAL1058 4.6 19.0 0.3
CA A:HIS1036 4.7 11.4 1.0
CB A:ILE1055 4.7 16.7 1.0
C A:CYS1034 4.8 17.6 1.0
O A:CYS1034 4.8 19.5 1.0
C A:ILE1055 4.9 18.8 1.0
C A:CYS1056 4.9 19.3 1.0
CD1 A:ILE1031 4.9 17.6 1.0
N A:ASP1057 4.9 17.9 1.0
N A:ILE1055 5.0 15.7 1.0

Zinc binding site 3 out of 4 in 6wi7

Go back to Zinc Binding Sites List in 6wi7
Zinc binding site 3 out of 4 in the RING1B-BMI1 Fusion in Closed Conformation


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of RING1B-BMI1 Fusion in Closed Conformation within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1203

b:16.8
occ:1.00
ND1 A:HIS69 2.0 14.2 1.0
SG A:CYS87 2.3 16.4 1.0
SG A:CYS67 2.3 16.8 1.0
SG A:CYS90 2.4 17.7 1.0
CE1 A:HIS69 2.9 19.2 1.0
CG A:HIS69 3.2 16.4 1.0
CB A:CYS87 3.2 18.8 1.0
CB A:CYS67 3.2 15.9 1.0
CB A:CYS90 3.5 19.1 1.0
CB A:HIS69 3.6 12.4 1.0
N A:CYS90 3.8 15.3 1.0
NE2 A:HIS69 4.1 16.9 1.0
CA A:CYS90 4.2 16.2 1.0
CD2 A:HIS69 4.2 14.2 1.0
OG1 A:THR64 4.2 15.0 1.0
CB A:THR89 4.5 16.1 1.0
CA A:CYS67 4.5 13.0 1.0
O A:HOH1494 4.6 35.5 1.0
CA A:CYS87 4.6 18.1 1.0
O A:CYS67 4.7 15.0 1.0
C A:THR89 4.7 18.2 1.0
C A:CYS67 4.7 13.6 1.0
C A:CYS90 4.8 17.9 1.0
N A:THR89 4.9 16.7 1.0
CA A:HIS69 4.9 11.3 1.0
N A:HIS69 4.9 13.0 1.0
CA A:THR89 4.9 17.0 1.0
N A:ARG91 4.9 16.9 1.0
CG2 A:THR64 5.0 12.7 1.0
CB A:LYS92 5.0 16.9 1.0

Zinc binding site 4 out of 4 in 6wi7

Go back to Zinc Binding Sites List in 6wi7
Zinc binding site 4 out of 4 in the RING1B-BMI1 Fusion in Closed Conformation


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of RING1B-BMI1 Fusion in Closed Conformation within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1204

b:15.6
occ:1.00
SG A:CYS75 2.3 15.2 1.0
SG A:CYS54 2.3 16.2 1.0
SG A:CYS51 2.4 13.9 1.0
SG A:CYS72 2.4 15.6 1.0
CB A:CYS51 3.0 12.1 1.0
CB A:CYS72 3.1 16.4 1.0
CB A:CYS54 3.3 15.3 1.0
CB A:CYS75 3.3 13.8 1.0
N A:CYS54 3.8 16.7 1.0
N A:CYS72 4.0 13.1 1.0
O A:HOH1547 4.1 39.4 1.0
CA A:CYS54 4.1 16.5 1.0
CA A:CYS72 4.2 13.5 1.0
CA A:CYS51 4.5 12.4 1.0
O A:HOH1468 4.5 36.2 1.0
CA A:CYS75 4.7 14.5 1.0
O A:HOH1416 4.7 32.5 1.0
CB A:ILE53 4.8 15.8 1.0
C A:ILE53 4.9 19.4 1.0
C A:CYS51 5.0 15.6 1.0
C A:CYS54 5.0 16.8 1.0
N A:CYS75 5.0 14.2 1.0

Reference:

H.J.Cho, T.Cierpicki. RING1B-BMI1 Domain Structure To Be Published.
Page generated: Sat Apr 17 17:42:48 2021

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy