Zinc in PDB 6v5m: Crystal Structure of Metallo Beta Lactamase From Hirschia Baltica in Complex with Succinate

All present enzymatic activity of Crystal Structure of Metallo Beta Lactamase From Hirschia Baltica in Complex with Succinate:
3.5.2.6;

The structure of Crystal Structure of Metallo Beta Lactamase From Hirschia Baltica in Complex with Succinate, PDB code: 6v5m was solved by N.Maltseva, Y.Kim, S.Clancy, M.Endres, R.Mulligan, A.Joachimiak, Center Forstructural Genomics Of Infectious Diseases (Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.31 / 1.50
Space group	H 3 2
Cell size a, b, c (Å), α, β, γ (°)	77.609, 77.609, 241.883, 90.00, 90.00, 120.00
R / Rfree (%)	14.2 / 16.7

The binding sites of Zinc atom in the Crystal Structure of Metallo Beta Lactamase From Hirschia Baltica in Complex with Succinate (pdb code 6v5m). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Metallo Beta Lactamase From Hirschia Baltica in Complex with Succinate, PDB code: 6v5m:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Metallo Beta Lactamase From Hirschia Baltica in Complex with Succinate


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Metallo Beta Lactamase From Hirschia Baltica in Complex with Succinate within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:21.0 occ:1.00 O A:HOH489 2.0 20.0 1.0 NE2 A:HIS241 2.1 18.3 1.0 OD2 A:ASP120 2.1 20.4 1.0 O1 A:SIN303 2.2 23.8 1.0 SG A:CYS199 2.3 18.6 1.0 CD2 A:HIS241 3.1 19.1 1.0 CE1 A:HIS241 3.1 21.6 1.0 C1 A:SIN303 3.2 25.4 0.8 CG A:ASP120 3.2 19.9 1.0 CB A:CYS199 3.4 19.1 1.0 OD1 A:ASP120 3.5 21.1 1.0 C2 A:SIN303 3.5 27.9 1.0 ZN A:ZN302 3.5 18.5 1.0 O A:HOH523 4.2 30.7 1.0 ND1 A:HIS241 4.2 19.4 1.0 NE2 A:HIS180 4.2 17.9 1.0 CG A:HIS241 4.2 19.8 1.0 O2 A:SIN303 4.3 26.0 1.0 CE1 A:HIS180 4.3 19.5 1.0 CB A:SER240 4.4 20.9 1.0 CE1 A:HIS116 4.4 19.9 1.0 O A:HOH468 4.4 23.1 1.0 CB A:ASP120 4.5 19.1 1.0 NE2 A:HIS116 4.5 17.8 1.0 CA A:CYS199 4.5 19.3 1.0 OG A:SER240 4.7 20.1 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Metallo Beta Lactamase From Hirschia Baltica in Complex with Succinate


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Metallo Beta Lactamase From Hirschia Baltica in Complex with Succinate within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn302 b:18.5 occ:0.96 O A:HOH489 2.0 20.0 1.0 ND1 A:HIS118 2.0 18.0 1.0 NE2 A:HIS180 2.0 17.9 1.0 NE2 A:HIS116 2.0 17.8 1.0 CE1 A:HIS116 3.0 19.9 1.0 CE1 A:HIS118 3.0 21.0 1.0 CD2 A:HIS180 3.0 19.8 1.0 CG A:HIS118 3.0 19.0 1.0 CE1 A:HIS180 3.0 19.5 1.0 CD2 A:HIS116 3.0 18.0 1.0 CB A:HIS118 3.3 17.5 1.0 ZN A:ZN301 3.5 21.0 1.0 O A:HOH523 3.7 30.7 1.0 OD1 A:ASP120 3.9 21.1 1.0 O1 A:SIN303 4.0 23.8 1.0 SG A:CYS199 4.0 18.6 1.0 CB A:CYS199 4.1 19.1 1.0 ND1 A:HIS116 4.1 18.7 1.0 NE2 A:HIS118 4.1 19.9 1.0 ND1 A:HIS180 4.1 19.9 1.0 CD2 A:HIS118 4.1 19.2 1.0 CG A:HIS180 4.1 20.1 1.0 CG A:HIS116 4.1 17.8 1.0 OD2 A:ASP120 4.5 20.4 1.0 CG A:ASP120 4.6 19.9 1.0 CA A:HIS118 4.8 17.4 1.0 C1 A:SIN303 4.8 25.4 0.8 ND2 A:ASN211 4.9 28.0 1.0

N.Maltseva, Y.Kim, S.Clancy, M.Endres, R.Mulligan, A.Joachimiak, Center For Structural Genomics Of Infectious Diseases(Csgid). Crystal Structure of Metallo Beta Lactamase From Hirschia Baltica in Complex with Succinate. To Be Published.