Zinc in PDB 6t35: Crystal Structure of Ampc From E.Coli with Enmetazobactam (Aai-101)

All present enzymatic activity of Crystal Structure of Ampc From E.Coli with Enmetazobactam (Aai-101):
3.5.2.6;

The structure of Crystal Structure of Ampc From E.Coli with Enmetazobactam (Aai-101), PDB code: 6t35 was solved by P.A.Lang, T.M.Leissing, C.J.Schofield, J.Brem, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.64 / 1.75
Space group	P 43 3 2
Cell size a, b, c (Å), α, β, γ (°)	138.000, 138.000, 138.000, 90.00, 90.00, 90.00
R / Rfree (%)	16.7 / 18.4

The structure of Crystal Structure of Ampc From E.Coli with Enmetazobactam (Aai-101) also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Zinc atom in the Crystal Structure of Ampc From E.Coli with Enmetazobactam (Aai-101) (pdb code 6t35). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Crystal Structure of Ampc From E.Coli with Enmetazobactam (Aai-101), PDB code: 6t35:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Crystal Structure of Ampc From E.Coli with Enmetazobactam (Aai-101)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Ampc From E.Coli with Enmetazobactam (Aai-101) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn405 b:22.4 occ:0.33 NE2 A:HIS13 2.1 31.6 1.0 CL A:CL408 2.3 28.7 0.3 CD2 A:HIS13 3.0 26.2 1.0 CE1 A:HIS13 3.1 26.6 1.0 ND1 A:HIS13 4.1 25.8 1.0 CG A:HIS13 4.2 25.6 1.0

Zinc binding site 2 out of 3 in the Crystal Structure of Ampc From E.Coli with Enmetazobactam (Aai-101)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Ampc From E.Coli with Enmetazobactam (Aai-101) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn406 b:57.6 occ:0.60 NE2 A:HIS186 2.4 56.0 1.0 CD2 A:HIS186 3.2 55.5 1.0 CE1 A:HIS186 3.4 57.9 1.0 OE2 A:GLU195 3.9 62.2 1.0 OE1 A:GLU195 4.2 58.0 1.0 CG A:HIS186 4.4 49.7 1.0 ND1 A:HIS186 4.5 53.5 1.0 CD A:GLU195 4.5 61.9 1.0

Zinc binding site 3 out of 3 in the Crystal Structure of Ampc From E.Coli with Enmetazobactam (Aai-101)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of Ampc From E.Coli with Enmetazobactam (Aai-101) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn407 b:76.0 occ:0.50 O A:HOH638 1.9 55.6 1.0 OD1 A:ASP229 2.3 37.5 1.0 O A:HOH620 2.3 42.1 1.0 ND1 A:HIS186 2.4 53.5 1.0 CG A:ASP229 3.1 34.1 1.0 CG A:HIS186 3.3 49.7 1.0 CE1 A:HIS186 3.4 57.9 1.0 OD2 A:ASP229 3.4 34.4 1.0 CB A:HIS186 3.5 39.9 1.0 O A:HOH602 3.7 53.1 1.0 N A:HIS186 3.7 38.2 1.0 N A:ASN185 4.2 35.5 1.0 O A:HOH710 4.2 50.9 1.0 CA A:HIS186 4.2 37.6 1.0 OG1 A:THR226 4.3 30.2 1.0 C A:ASN185 4.4 39.4 1.0 CB A:ASP229 4.4 28.8 1.0 NE2 A:HIS186 4.5 56.0 1.0 CD2 A:HIS186 4.5 55.5 1.0 CA A:ASN185 4.6 39.9 1.0 CB A:ASN185 4.7 47.0 1.0 OE1 A:GLU228 4.7 59.2 1.0 N A:ASP229 4.7 28.9 1.0 CA A:ASP229 4.9 27.8 1.0 O A:LYS183 4.9 40.5 1.0 CB A:GLU228 5.0 36.6 1.0

P.A.Lang, T.M.Leissing, C.J.Schofield, J.Brem. Crystal Structure of Ampc From E.Coli with Enmetazobactam (Aai-101) To Be Published.