Zinc in PDB 6t0b: The III2-IV(5B)2 Respiratory Supercomplex From S. Cerevisiae

All present enzymatic activity of The III2-IV(5B)2 Respiratory Supercomplex From S. Cerevisiae:
1.9.3.1; 7.1.1.8;

The structure of The III2-IV(5B)2 Respiratory Supercomplex From S. Cerevisiae also contains other interesting chemical elements:

Magnesium	(Mg)	2 atoms
Iron	(Fe)	14 atoms
Calcium	(Ca)	2 atoms
Copper	(Cu)	6 atoms

The binding sites of Zinc atom in the The III2-IV(5B)2 Respiratory Supercomplex From S. Cerevisiae (pdb code 6t0b). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the The III2-IV(5B)2 Respiratory Supercomplex From S. Cerevisiae, PDB code: 6t0b:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the The III2-IV(5B)2 Respiratory Supercomplex From S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The III2-IV(5B)2 Respiratory Supercomplex From S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ d:Zn201 b:77.9 occ:1.00 NE2 d:HIS119 2.2 69.2 1.0 CE1 d:HIS119 2.3 69.2 1.0 SG d:CYS134 2.4 68.5 1.0 SG d:CYS137 2.4 69.8 1.0 SG d:CYS111 2.5 69.2 1.0 CB d:CYS137 3.1 69.8 1.0 N d:CYS137 3.4 69.8 1.0 ND1 d:HIS119 3.5 69.2 1.0 CB d:CYS134 3.5 68.5 1.0 CD2 d:HIS119 3.5 69.2 1.0 CB d:CYS111 3.6 69.2 1.0 CA d:CYS137 3.8 69.8 1.0 CG d:HIS119 4.1 69.2 1.0 N d:GLY113 4.2 70.8 1.0 C d:CYS111 4.4 69.2 1.0 N d:GLY138 4.4 67.3 1.0 CB d:GLU136 4.5 69.8 1.0 C d:GLU136 4.5 69.8 1.0 N d:THR112 4.5 71.7 1.0 C d:CYS137 4.5 69.8 1.0 O d:CYS111 4.5 69.2 1.0 OG d:SER139 4.6 67.5 1.0 CA d:CYS111 4.6 69.2 1.0 CA d:GLY113 4.6 70.8 1.0 C d:THR112 4.7 71.7 1.0 CA d:GLU136 4.8 69.8 1.0 CA d:THR112 4.9 71.7 1.0 CA d:CYS134 4.9 68.5 1.0 N d:GLU136 4.9 69.8 1.0 CG d:GLU136 4.9 69.8 1.0

Zinc binding site 2 out of 2 in the The III2-IV(5B)2 Respiratory Supercomplex From S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The III2-IV(5B)2 Respiratory Supercomplex From S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ q:Zn201 b:0.3 occ:1.00 NE2 q:HIS119 2.2 0.9 1.0 CE1 q:HIS119 2.2 0.9 1.0 SG q:CYS134 2.4 1.0 1.0 SG q:CYS111 2.4 0.3 1.0 SG q:CYS137 2.4 0.0 1.0 CB q:CYS137 3.2 0.0 1.0 N q:CYS137 3.4 0.0 1.0 CD2 q:HIS119 3.5 0.9 1.0 ND1 q:HIS119 3.5 0.9 1.0 CB q:CYS134 3.7 1.0 1.0 CA q:CYS137 3.9 0.0 1.0 CB q:CYS111 3.9 0.3 1.0 OG q:SER139 4.1 0.0 1.0 CG q:HIS119 4.1 0.9 1.0 N q:GLY113 4.2 0.0 1.0 CB q:GLU136 4.4 0.1 1.0 C q:THR112 4.5 0.2 1.0 C q:GLU136 4.5 0.1 1.0 CA q:GLY113 4.5 0.0 1.0 N q:GLY138 4.6 0.6 1.0 C q:CYS111 4.6 0.3 1.0 C q:CYS137 4.7 0.0 1.0 N q:THR112 4.7 0.2 1.0 O q:CYS111 4.8 0.3 1.0 CA q:GLU136 4.8 0.1 1.0 CA q:THR112 4.9 0.2 1.0 O q:THR112 4.9 0.2 1.0 N q:GLU136 4.9 0.1 1.0 CA q:CYS111 4.9 0.3 1.0

A.M.Hartley, B.Meunier, N.Pinotsis, A.Marechal. RCF2 Revealed in Cryo-Em Structures of Hypoxic Isoforms of Mature Mitochondrial III-IV Supercomplexes. Proc.Natl.Acad.Sci.Usa 2020.
ISSN: ESSN 1091-6490
PubMed: 32291341
DOI: 10.1073/PNAS.1920612117