Atomistry » Zinc » PDB 6sqs-6t5q » 6syb
Atomistry »
  Zinc »
    PDB 6sqs-6t5q »
      6syb »

Zinc in PDB 6syb: Crystal Structure of Carbonic Anhydrase 2 with (3AR,4S,9BS)-4-(2- Chloro-4-Hydroxyphenyl)-3A,4,5,9B-Tetrahydro-3H- Cyclopenta[C]Quinoline-8-Sulfonamide

Enzymatic activity of Crystal Structure of Carbonic Anhydrase 2 with (3AR,4S,9BS)-4-(2- Chloro-4-Hydroxyphenyl)-3A,4,5,9B-Tetrahydro-3H- Cyclopenta[C]Quinoline-8-Sulfonamide

All present enzymatic activity of Crystal Structure of Carbonic Anhydrase 2 with (3AR,4S,9BS)-4-(2- Chloro-4-Hydroxyphenyl)-3A,4,5,9B-Tetrahydro-3H- Cyclopenta[C]Quinoline-8-Sulfonamide:
4.2.1.1;

Protein crystallography data

The structure of Crystal Structure of Carbonic Anhydrase 2 with (3AR,4S,9BS)-4-(2- Chloro-4-Hydroxyphenyl)-3A,4,5,9B-Tetrahydro-3H- Cyclopenta[C]Quinoline-8-Sulfonamide, PDB code: 6syb was solved by A.Angeli, M.Ferraroni, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 69.68 / 1.60
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 42.290, 41.305, 71.935, 90.00, 104.40, 90.00
R / Rfree (%) 17.4 / 21.6

Other elements in 6syb:

The structure of Crystal Structure of Carbonic Anhydrase 2 with (3AR,4S,9BS)-4-(2- Chloro-4-Hydroxyphenyl)-3A,4,5,9B-Tetrahydro-3H- Cyclopenta[C]Quinoline-8-Sulfonamide also contains other interesting chemical elements:

Chlorine (Cl) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Carbonic Anhydrase 2 with (3AR,4S,9BS)-4-(2- Chloro-4-Hydroxyphenyl)-3A,4,5,9B-Tetrahydro-3H- Cyclopenta[C]Quinoline-8-Sulfonamide (pdb code 6syb). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Carbonic Anhydrase 2 with (3AR,4S,9BS)-4-(2- Chloro-4-Hydroxyphenyl)-3A,4,5,9B-Tetrahydro-3H- Cyclopenta[C]Quinoline-8-Sulfonamide, PDB code: 6syb:

Zinc binding site 1 out of 1 in 6syb

Go back to Zinc Binding Sites List in 6syb
Zinc binding site 1 out of 1 in the Crystal Structure of Carbonic Anhydrase 2 with (3AR,4S,9BS)-4-(2- Chloro-4-Hydroxyphenyl)-3A,4,5,9B-Tetrahydro-3H- Cyclopenta[C]Quinoline-8-Sulfonamide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Carbonic Anhydrase 2 with (3AR,4S,9BS)-4-(2- Chloro-4-Hydroxyphenyl)-3A,4,5,9B-Tetrahydro-3H- Cyclopenta[C]Quinoline-8-Sulfonamide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn301

b:9.4
occ:1.00
 N1 A:LYQ303 2.0 10.2 1.0
NE2 A:HIS94 2.0 10.1 1.0
ND1 A:HIS119 2.0 8.2 1.0
NE2 A:HIS96 2.1 9.3 1.0
CE1 A:HIS119 2.9 9.0 1.0
CD2 A:HIS94 3.0 8.8 1.0
CD2 A:HIS96 3.0 9.4 1.0
O2 A:LYQ303 3.0 12.2 1.0
S A:LYQ303 3.1 11.7 1.0
CE1 A:HIS94 3.1 9.5 1.0
CE1 A:HIS96 3.1 10.4 1.0
CG A:HIS119 3.2 8.4 1.0
CB A:HIS119 3.6 9.0 1.0
OG1 A:THR199 3.9 8.8 1.0
OE1 A:GLU106 4.0 9.8 1.0
O1 A:LYQ303 4.1 11.9 1.0
NE2 A:HIS119 4.1 8.8 1.0
CG A:HIS94 4.1 9.2 1.0
ND1 A:HIS94 4.2 9.4 1.0
CG A:HIS96 4.2 9.8 1.0
ND1 A:HIS96 4.2 10.1 1.0
CD2 A:HIS119 4.2 8.5 1.0
C16 A:LYQ303 4.3 14.0 1.0
C3 A:GOL302 4.4 25.7 1.0
C15 A:LYQ303 4.8 17.1 1.0
CD A:GLU106 5.0 10.2 1.0

Reference:

A.Angeli, M.Ferraroni. Crystal Structure of Carbonic Anhydrase 2 with (3AR,4S,9BS)-4-(2-Chloro-4-Hydroxyphenyl)-3A,4,5, 9B-Tetrahydro-3H-Cyclopenta[C]Quinoline-8-Sulfonamide To Be Published.
Page generated: Tue Oct 29 07:44:31 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy