Zinc in PDB 6smv: Structure of HPV49 E6 Protein in Complex with MAML1 Lxxll Motif

The structure of Structure of HPV49 E6 Protein in Complex with MAML1 Lxxll Motif, PDB code: 6smv was solved by I.P.Suarez, A.Cousido-Siah, A.Bonhoure, C.Kostmann, A.Mitschler, A.Podjarny, G.Trave, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.44 / 2.14
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	73.906, 44.539, 94.237, 90.00, 99.70, 90.00
R / Rfree (%)	26.9 / 30.8

The binding sites of Zinc atom in the Structure of HPV49 E6 Protein in Complex with MAML1 Lxxll Motif (pdb code 6smv). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of HPV49 E6 Protein in Complex with MAML1 Lxxll Motif, PDB code: 6smv:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of HPV49 E6 Protein in Complex with MAML1 Lxxll Motif


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of HPV49 E6 Protein in Complex with MAML1 Lxxll Motif within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2101 b:47.2 occ:1.00 SG A:CYS1134 2.3 42.4 1.0 SG A:CYS1131 2.3 39.1 1.0 SG A:CYS1098 2.3 40.4 1.0 SG A:CYS1101 2.3 35.1 1.0 CB A:CYS1098 3.2 33.3 1.0 CB A:CYS1134 3.2 52.1 1.0 CB A:CYS1101 3.3 32.5 1.0 CB A:CYS1131 3.4 41.4 1.0 N A:CYS1101 3.7 38.0 1.0 CA A:CYS1101 4.1 45.1 1.0 N A:CYS1134 4.1 44.3 1.0 N A:CYS1131 4.2 30.3 1.0 CA A:CYS1134 4.3 49.7 1.0 CA A:CYS1131 4.3 34.7 1.0 CB A:ILE1100 4.5 40.5 1.0 CA A:CYS1098 4.6 39.1 1.0 C A:ILE1100 4.8 37.4 1.0 C A:CYS1101 4.8 44.5 1.0 C A:CYS1131 4.9 35.8 1.0 CG A:LYS1103 5.0 35.2 1.0 N A:LEU1102 5.0 34.8 1.0

Zinc binding site 2 out of 2 in the Structure of HPV49 E6 Protein in Complex with MAML1 Lxxll Motif


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of HPV49 E6 Protein in Complex with MAML1 Lxxll Motif within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2102 b:45.2 occ:1.00 SG A:CYS1028 2.3 37.3 1.0 SG A:CYS1061 2.3 41.0 1.0 SG A:CYS1058 2.3 35.0 1.0 SG A:CYS1025 2.5 33.6 1.0 CB A:CYS1061 3.2 37.2 1.0 CB A:CYS1028 3.3 29.5 1.0 CB A:CYS1025 3.3 32.5 1.0 CB A:CYS1058 3.6 31.2 1.0 N A:CYS1028 3.7 38.9 1.0 CA A:CYS1028 4.0 39.4 1.0 N A:CYS1058 4.0 27.1 1.0 O A:HOH2267 4.2 42.3 1.0 C A:PHE1027 4.3 35.6 1.0 N A:CYS1061 4.3 42.6 1.0 CA A:CYS1061 4.3 40.1 1.0 O A:HOH2257 4.4 36.9 1.0 CA A:CYS1058 4.4 32.9 1.0 CB A:PHE1027 4.7 38.0 1.0 C A:CYS1028 4.7 34.7 1.0 N A:PHE1027 4.7 31.9 1.0 CA A:PHE1027 4.8 33.1 1.0 CA A:CYS1025 4.8 30.2 1.0 O A:CYS1028 4.9 33.0 1.0 O A:PHE1027 4.9 42.5 1.0 C A:CYS1058 5.0 40.6 1.0

I.P.Suarez, A.Bonhoure, A.Cousido-Siah, Y.Chebaro, C.Kostmann, P.Eberling, D.Altschuh, A.Mitschler, A.Podjarny, G.Trave. Cellular Target Recognition By HPV18 and HPV49 Oncoproteins To Be Published.