Zinc in PDB 6s1y: Crystal Structure of Anopheles Gambiae ANOACE2 in Complex with Gamma- Polyglutamic Acid.

The structure of Crystal Structure of Anopheles Gambiae ANOACE2 in Complex with Gamma- Polyglutamic Acid., PDB code: 6s1y was solved by G.E.Cozier, K.R.Acharya, J.S.Cashman, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	91.76 / 2.20
Space group	P 62 2 2
Cell size a, b, c (Å), α, β, γ (°)	160.972, 160.972, 121.888, 90.00, 90.00, 120.00
R / Rfree (%)	19.4 / 24.1

The binding sites of Zinc atom in the Crystal Structure of Anopheles Gambiae ANOACE2 in Complex with Gamma- Polyglutamic Acid. (pdb code 6s1y). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Anopheles Gambiae ANOACE2 in Complex with Gamma- Polyglutamic Acid., PDB code: 6s1y:

Zinc binding site 1 out of 1 in the Crystal Structure of Anopheles Gambiae ANOACE2 in Complex with Gamma- Polyglutamic Acid.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Anopheles Gambiae ANOACE2 in Complex with Gamma- Polyglutamic Acid. within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn709 b:45.3 occ:1.00 O15 A:KSN710 1.9 46.9 0.6 OE1 A:GLU411 1.9 44.8 1.0 NE2 A:HIS383 2.0 44.4 1.0 NE2 A:HIS387 2.0 46.6 1.0 O15 A:KSN710 2.0 47.1 0.4 O14 A:KSN710 2.5 46.2 0.6 O14 A:KSN710 2.5 47.0 0.4 C13 A:KSN710 2.5 46.7 0.6 C13 A:KSN710 2.5 46.9 0.4 CE1 A:HIS383 2.8 44.7 1.0 CD A:GLU411 2.9 45.8 1.0 CE1 A:HIS387 2.9 45.5 1.0 HE1 A:HIS383 3.0 53.8 1.0 CD2 A:HIS387 3.0 44.3 1.0 CD2 A:HIS383 3.1 44.4 1.0 HE1 A:TYR523 3.1 53.1 1.0 HE1 A:HIS387 3.1 54.6 1.0 OE2 A:GLU411 3.2 46.7 1.0 HD2 A:HIS387 3.2 53.2 1.0 HD2 A:HIS383 3.3 53.4 1.0 HH A:TYR523 3.5 55.3 1.0 HA A:GLU411 3.6 55.3 1.0 CE1 A:TYR523 3.9 44.2 1.0 C07 A:KSN710 4.0 48.4 0.4 ND1 A:HIS383 4.0 45.6 1.0 H061 A:KSN710 4.0 57.6 0.4 C07 A:KSN710 4.0 48.5 0.6 ND1 A:HIS387 4.1 46.1 1.0 N06 A:KSN710 4.1 47.9 0.4 CG A:HIS383 4.1 44.6 1.0 CG A:HIS387 4.1 44.9 1.0 OH A:TYR523 4.2 46.1 1.0 CG A:GLU411 4.3 44.8 1.0 HB3 A:GLU411 4.3 54.7 1.0 O A:HOH830 4.4 47.4 1.0 H071 A:KSN710 4.5 58.1 0.4 H071 A:KSN710 4.5 58.3 0.6 H092 A:KSN710 4.5 60.9 0.6 CA A:GLU411 4.5 46.0 1.0 N06 A:KSN710 4.5 47.4 0.6 CZ A:TYR523 4.5 45.2 1.0 CB A:GLU411 4.6 45.6 1.0 H032 A:KSN710 4.6 56.5 0.4 H032 A:KSN710 4.7 56.4 0.6 OE2 A:GLU384 4.7 46.0 1.0 H031 A:KSN710 4.7 56.4 0.6 HG3 A:GLU411 4.7 53.8 1.0 HD1 A:HIS383 4.7 54.7 1.0 H082 A:KSN710 4.8 58.9 0.4 H061 A:KSN710 4.8 57.0 0.6 HD1 A:HIS387 4.8 55.4 1.0 HG2 A:GLU411 4.9 53.8 1.0 HO2 A:EDO708 4.9 80.8 1.0 HD1 A:TYR523 4.9 53.9 1.0 OE1 A:GLU384 4.9 45.2 1.0 C05 A:KSN710 4.9 47.2 0.4 CD1 A:TYR523 4.9 44.9 1.0 H082 A:KSN710 5.0 59.2 0.6 C08 A:KSN710 5.0 49.3 0.6

J.S.Cashman, G.E.Cozier, C.Harrison, R.E.Isaac, K.R.Acharya. Crystal Structures of Angiotensin-Converting Enzyme From Anopheles Gambiae in Its Native Form and with A Bound Inhibitor. Biochem.J. V. 476 3505 2019.
ISSN: ESSN 1470-8728
PubMed: 31682720
DOI: 10.1042/BCJ20190635