Zinc in PDB 6rz3: Crystal Structure of A Complex Between the Dna-Binding Domain of P53 and the Carboxyl-Terminal Conserved Region of Iaspp

The structure of Crystal Structure of A Complex Between the Dna-Binding Domain of P53 and the Carboxyl-Terminal Conserved Region of Iaspp, PDB code: 6rz3 was solved by S.Chen, J.Ren, E.Y.Jones, X.Lu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.80 / 4.23
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	71.090, 71.090, 255.589, 90.00, 90.00, 90.00
R / Rfree (%)	24.3 / 29.2

The binding sites of Zinc atom in the Crystal Structure of A Complex Between the Dna-Binding Domain of P53 and the Carboxyl-Terminal Conserved Region of Iaspp (pdb code 6rz3). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of A Complex Between the Dna-Binding Domain of P53 and the Carboxyl-Terminal Conserved Region of Iaspp, PDB code: 6rz3:

Zinc binding site 1 out of 1 in the Crystal Structure of A Complex Between the Dna-Binding Domain of P53 and the Carboxyl-Terminal Conserved Region of Iaspp


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of A Complex Between the Dna-Binding Domain of P53 and the Carboxyl-Terminal Conserved Region of Iaspp within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:0.6 occ:1.00 SG A:CYS238 2.1 0.0 1.0 ND1 A:HIS179 2.3 0.5 1.0 SG A:CYS176 2.4 0.7 1.0 SG A:CYS242 2.5 0.8 1.0 CB A:CYS242 2.8 0.9 1.0 CE1 A:HIS179 3.0 0.6 1.0 CB A:CYS176 3.2 0.9 1.0 CB A:CYS238 3.3 0.9 1.0 CG A:HIS179 3.5 0.4 1.0 N A:CYS176 3.7 0.2 1.0 CA A:CYS238 3.9 0.4 1.0 CB A:HIS179 4.0 0.2 1.0 CA A:CYS176 4.0 0.2 1.0 N A:ASN239 4.1 0.5 1.0 NE2 A:HIS179 4.2 0.7 1.0 CA A:CYS242 4.3 0.2 1.0 C A:CYS238 4.4 1.0 1.0 CD2 A:HIS179 4.5 0.4 1.0 O A:ASN239 4.6 0.1 1.0 C A:ARG175 4.9 0.8 1.0 C A:CYS176 4.9 0.6 1.0 N A:HIS179 4.9 0.3 1.0

S.Chen, J.Wu, S.Zhong, Y.Li, P.Zhang, J.Ma, J.Ren, Y.Tan, Y.Wang, K.F.Au, C.Siebold, G.L.Bond, Z.Chen, M.Lu, E.Y.Jones, X.Lu. Iaspp Mediates P53 Selectivity Through A Modular Mechanism Fine-Tuning Dna Recognition. Proc.Natl.Acad.Sci.Usa V. 116 17470 2019.
ISSN: ESSN 1091-6490
PubMed: 31395738
DOI: 10.1073/PNAS.1909393116