Zinc in PDB 6ryu: Nucleosome-CHD4 Complex Structure (Two CHD4 Copies)
Enzymatic activity of Nucleosome-CHD4 Complex Structure (Two CHD4 Copies)
All present enzymatic activity of Nucleosome-CHD4 Complex Structure (Two CHD4 Copies):
3.6.4.12;
Other elements in 6ryu:
The structure of Nucleosome-CHD4 Complex Structure (Two CHD4 Copies) also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Nucleosome-CHD4 Complex Structure (Two CHD4 Copies)
(pdb code 6ryu). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the
Nucleosome-CHD4 Complex Structure (Two CHD4 Copies), PDB code: 6ryu:
Jump to Zinc binding site number:
1;
2;
3;
4;
Zinc binding site 1 out
of 4 in 6ryu
Go back to
Zinc Binding Sites List in 6ryu
Zinc binding site 1 out
of 4 in the Nucleosome-CHD4 Complex Structure (Two CHD4 Copies)
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Nucleosome-CHD4 Complex Structure (Two CHD4 Copies) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
W:Zn2203
b:0.8
occ:1.00
|
SG
|
W:CYS455
|
2.5
|
0.1
|
1.0
|
CB
|
W:HIS472
|
2.6
|
0.8
|
1.0
|
SG
|
W:CYS452
|
2.6
|
0.6
|
1.0
|
SG
|
W:CYS475
|
2.6
|
0.5
|
1.0
|
CB
|
W:CYS452
|
3.0
|
0.6
|
1.0
|
CB
|
W:CYS475
|
3.4
|
0.5
|
1.0
|
N
|
W:HIS472
|
3.5
|
0.8
|
1.0
|
CA
|
W:HIS472
|
3.6
|
0.8
|
1.0
|
CG
|
W:HIS472
|
3.6
|
0.8
|
1.0
|
ND1
|
W:HIS472
|
3.8
|
0.8
|
1.0
|
CB
|
W:CYS455
|
4.0
|
0.1
|
1.0
|
N
|
W:CYS455
|
4.4
|
0.1
|
1.0
|
C
|
W:HIS472
|
4.4
|
0.8
|
1.0
|
O
|
W:HIS472
|
4.4
|
0.8
|
1.0
|
CA
|
W:CYS452
|
4.6
|
0.6
|
1.0
|
C
|
W:TYR471
|
4.7
|
0.8
|
1.0
|
CE1
|
W:HIS474
|
4.7
|
0.3
|
1.0
|
CA
|
W:CYS475
|
4.8
|
0.5
|
1.0
|
CA
|
W:CYS455
|
4.8
|
0.1
|
1.0
|
CD2
|
W:HIS472
|
5.0
|
0.8
|
1.0
|
CB
|
W:VAL454
|
5.0
|
0.8
|
1.0
|
N
|
W:CYS475
|
5.0
|
0.5
|
1.0
|
|
Zinc binding site 2 out
of 4 in 6ryu
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Zinc Binding Sites List in 6ryu
Zinc binding site 2 out
of 4 in the Nucleosome-CHD4 Complex Structure (Two CHD4 Copies)
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Nucleosome-CHD4 Complex Structure (Two CHD4 Copies) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
W:Zn2204
b:0.9
occ:1.00
|
SG
|
W:CYS467
|
2.3
|
0.2
|
1.0
|
SG
|
W:CYS493
|
2.3
|
0.3
|
1.0
|
SG
|
W:CYS490
|
2.4
|
0.8
|
1.0
|
SG
|
W:CYS464
|
2.4
|
0.4
|
1.0
|
CB
|
W:CYS464
|
3.1
|
0.4
|
1.0
|
CB
|
W:CYS490
|
3.1
|
0.8
|
1.0
|
OG
|
W:SER469
|
3.5
|
0.3
|
1.0
|
CB
|
W:CYS467
|
3.6
|
0.2
|
1.0
|
CB
|
W:SER469
|
3.7
|
0.3
|
1.0
|
N
|
W:CYS490
|
3.8
|
0.8
|
1.0
|
CB
|
W:CYS493
|
3.9
|
0.3
|
1.0
|
CA
|
W:CYS490
|
4.0
|
0.8
|
1.0
|
N
|
W:CYS467
|
4.1
|
0.2
|
1.0
|
CA
|
W:CYS467
|
4.3
|
0.2
|
1.0
|
O
|
W:CYS467
|
4.3
|
0.2
|
1.0
|
N
|
W:CYS493
|
4.3
|
0.3
|
1.0
|
C
|
W:CYS467
|
4.5
|
0.2
|
1.0
|
CA
|
W:CYS464
|
4.5
|
0.4
|
1.0
|
N
|
W:SER469
|
4.6
|
0.3
|
1.0
|
CA
|
W:CYS493
|
4.7
|
0.3
|
1.0
|
C
|
W:CYS490
|
4.7
|
0.8
|
1.0
|
O
|
W:CYS490
|
4.7
|
0.8
|
1.0
|
C
|
W:THR466
|
4.7
|
0.9
|
1.0
|
CA
|
W:SER469
|
4.8
|
0.3
|
1.0
|
CG2
|
W:THR466
|
4.8
|
0.9
|
1.0
|
N
|
W:THR466
|
5.0
|
0.9
|
1.0
|
|
Zinc binding site 3 out
of 4 in 6ryu
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Zinc Binding Sites List in 6ryu
Zinc binding site 3 out
of 4 in the Nucleosome-CHD4 Complex Structure (Two CHD4 Copies)
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Nucleosome-CHD4 Complex Structure (Two CHD4 Copies) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
V:Zn2203
b:0.7
occ:1.00
|
SG
|
V:CYS455
|
2.5
|
0.9
|
1.0
|
SG
|
V:CYS452
|
2.6
|
1.0
|
1.0
|
CB
|
V:HIS472
|
2.6
|
0.5
|
1.0
|
SG
|
V:CYS475
|
2.6
|
0.3
|
1.0
|
CB
|
V:CYS452
|
3.0
|
1.0
|
1.0
|
CB
|
V:CYS475
|
3.4
|
0.3
|
1.0
|
N
|
V:HIS472
|
3.5
|
0.5
|
1.0
|
CA
|
V:HIS472
|
3.6
|
0.5
|
1.0
|
CG
|
V:HIS472
|
3.6
|
0.5
|
1.0
|
ND1
|
V:HIS472
|
3.8
|
0.5
|
1.0
|
CB
|
V:CYS455
|
4.0
|
0.9
|
1.0
|
N
|
V:CYS455
|
4.4
|
0.9
|
1.0
|
C
|
V:HIS472
|
4.4
|
0.5
|
1.0
|
O
|
V:HIS472
|
4.4
|
0.5
|
1.0
|
CA
|
V:CYS452
|
4.6
|
1.0
|
1.0
|
C
|
V:TYR471
|
4.7
|
1.0
|
1.0
|
CE1
|
V:HIS474
|
4.7
|
0.9
|
1.0
|
CA
|
V:CYS475
|
4.8
|
0.3
|
1.0
|
CA
|
V:CYS455
|
4.8
|
0.9
|
1.0
|
CD2
|
V:HIS472
|
5.0
|
0.5
|
1.0
|
CB
|
V:VAL454
|
5.0
|
0.6
|
1.0
|
N
|
V:CYS475
|
5.0
|
0.3
|
1.0
|
|
Zinc binding site 4 out
of 4 in 6ryu
Go back to
Zinc Binding Sites List in 6ryu
Zinc binding site 4 out
of 4 in the Nucleosome-CHD4 Complex Structure (Two CHD4 Copies)
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Nucleosome-CHD4 Complex Structure (Two CHD4 Copies) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
V:Zn2204
b:0.6
occ:1.00
|
SG
|
V:CYS467
|
2.3
|
0.2
|
1.0
|
SG
|
V:CYS493
|
2.3
|
0.6
|
1.0
|
SG
|
V:CYS490
|
2.4
|
0.0
|
1.0
|
SG
|
V:CYS464
|
2.4
|
0.5
|
1.0
|
CB
|
V:CYS464
|
3.1
|
0.5
|
1.0
|
CB
|
V:CYS490
|
3.1
|
0.0
|
1.0
|
OG
|
V:SER469
|
3.5
|
1.0
|
1.0
|
CB
|
V:CYS467
|
3.6
|
0.2
|
1.0
|
CB
|
V:SER469
|
3.7
|
1.0
|
1.0
|
N
|
V:CYS490
|
3.8
|
0.0
|
1.0
|
CB
|
V:CYS493
|
3.9
|
0.6
|
1.0
|
CA
|
V:CYS490
|
4.0
|
0.0
|
1.0
|
N
|
V:CYS467
|
4.1
|
0.2
|
1.0
|
CA
|
V:CYS467
|
4.3
|
0.2
|
1.0
|
O
|
V:CYS467
|
4.3
|
0.2
|
1.0
|
N
|
V:CYS493
|
4.3
|
0.6
|
1.0
|
C
|
V:CYS467
|
4.5
|
0.2
|
1.0
|
CA
|
V:CYS464
|
4.5
|
0.5
|
1.0
|
N
|
V:SER469
|
4.6
|
1.0
|
1.0
|
CA
|
V:CYS493
|
4.7
|
0.6
|
1.0
|
C
|
V:CYS490
|
4.7
|
0.0
|
1.0
|
O
|
V:CYS490
|
4.7
|
0.0
|
1.0
|
C
|
V:THR466
|
4.7
|
0.8
|
1.0
|
CA
|
V:SER469
|
4.8
|
1.0
|
1.0
|
CG2
|
V:THR466
|
4.8
|
0.8
|
1.0
|
N
|
V:THR466
|
5.0
|
0.8
|
1.0
|
|
Reference:
L.Farnung,
M.Ochmann,
P.Cramer.
Nucleosome-CHD4 Chromatin Remodeller Structure Maps Human Disease Mutations. Elife V. 9 2020.
ISSN: ESSN 2050-084X
PubMed: 32543371
DOI: 10.7554/ELIFE.56178
Page generated: Tue Oct 29 06:55:54 2024
|