Zinc in PDB 6rin: Cryo-Em Structure of E. Coli Rna Polymerase Backtracked Elongation Complex Bound to Greb Transcription Factor

All present enzymatic activity of Cryo-Em Structure of E. Coli Rna Polymerase Backtracked Elongation Complex Bound to Greb Transcription Factor:
2.7.7.6;

The structure of Cryo-Em Structure of E. Coli Rna Polymerase Backtracked Elongation Complex Bound to Greb Transcription Factor also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the Cryo-Em Structure of E. Coli Rna Polymerase Backtracked Elongation Complex Bound to Greb Transcription Factor (pdb code 6rin). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryo-Em Structure of E. Coli Rna Polymerase Backtracked Elongation Complex Bound to Greb Transcription Factor, PDB code: 6rin:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cryo-Em Structure of E. Coli Rna Polymerase Backtracked Elongation Complex Bound to Greb Transcription Factor


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of E. Coli Rna Polymerase Backtracked Elongation Complex Bound to Greb Transcription Factor within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1501 b:0.8 occ:1.00 SG D:CYS88 2.3 0.8 1.0 SG D:CYS72 2.3 0.8 1.0 SG D:CYS85 2.3 0.2 1.0 SG D:CYS70 2.4 0.7 1.0 CB D:CYS72 2.4 0.8 1.0 CB D:CYS85 2.9 0.2 1.0 N D:CYS72 3.3 0.8 1.0 CA D:CYS72 3.4 0.8 1.0 CB D:CYS88 3.7 0.8 1.0 CB D:CYS70 3.8 0.7 1.0 N D:CYS88 3.8 0.8 1.0 CA D:CYS88 4.2 0.8 1.0 CA D:CYS85 4.4 0.2 1.0 N D:GLY89 4.4 0.1 1.0 C D:CYS72 4.5 0.8 1.0 C D:LEU71 4.6 0.2 1.0 N D:LEU71 4.6 0.2 1.0 C D:CYS88 4.6 0.8 1.0 N D:GLY73 4.8 0.7 1.0 C D:LYS87 4.8 0.3 1.0 CB D:LYS87 4.9 0.3 1.0 N D:LYS87 4.9 0.3 1.0 C D:CYS70 4.9 0.7 1.0 CA D:CYS70 4.9 0.7 1.0

Zinc binding site 2 out of 2 in the Cryo-Em Structure of E. Coli Rna Polymerase Backtracked Elongation Complex Bound to Greb Transcription Factor


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of E. Coli Rna Polymerase Backtracked Elongation Complex Bound to Greb Transcription Factor within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1502 b:95.9 occ:1.00 SG D:CYS888 2.3 81.0 1.0 SG D:CYS895 2.4 61.9 1.0 SG D:CYS814 2.4 84.5 1.0 SG D:CYS898 2.5 59.8 1.0 CB D:CYS814 2.9 84.5 1.0 CB D:CYS888 3.0 81.0 1.0 CA D:CYS888 3.3 81.0 1.0 CB D:CYS898 3.4 59.8 1.0 CB D:CYS895 3.7 61.9 1.0 NH2 D:ARG883 3.8 69.2 1.0 N D:ASP889 3.8 88.8 1.0 C D:CYS888 4.1 81.0 1.0 CA D:CYS814 4.3 84.5 1.0 N D:CYS814 4.5 84.5 1.0 N D:CYS895 4.5 61.9 1.0 N D:CYS888 4.5 81.0 1.0 OG1 D:THR890 4.5 79.0 1.0 CA D:CYS895 4.6 61.9 1.0 CA D:CYS898 4.7 59.8 1.0 N D:CYS898 4.9 59.8 1.0 CZ D:ARG883 4.9 69.2 1.0 OG1 D:THR816 4.9 92.6 1.0

M.Abdelkareem, C.Saint-Andre, M.Takacs, G.Papai, C.Crucifix, X.Guo, J.Ortiz, A.Weixlbaumer. Structural Basis of Transcription: Rna Polymerase Backtracking and Its Reactivation. Mol.Cell V. 75 298 2019.
ISSN: ISSN 1097-2765
PubMed: 31103420
DOI: 10.1016/J.MOLCEL.2019.04.029