Zinc in PDB 6ptw: uc(Nmr) Data-Driven Model of Kras-Gmppnp:Rbd-Crd Complex Tethered to A Nanodisc (State B)

The structure of uc(Nmr) Data-Driven Model of Kras-Gmppnp:Rbd-Crd Complex Tethered to A Nanodisc (State B) also contains other interesting chemical elements:

Magnesium

(Mg)

10 atoms

The binding sites of Zinc atom in the uc(Nmr) Data-Driven Model of Kras-Gmppnp:Rbd-Crd Complex Tethered to A Nanodisc (State B) (pdb code 6ptw). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the uc(Nmr) Data-Driven Model of Kras-Gmppnp:Rbd-Crd Complex Tethered to A Nanodisc (State B), PDB code: 6ptw:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the uc(Nmr) Data-Driven Model of Kras-Gmppnp:Rbd-Crd Complex Tethered to A Nanodisc (State B)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of uc(Nmr) Data-Driven Model of Kras-Gmppnp:Rbd-Crd Complex Tethered to A Nanodisc (State B) within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn531 b:10.0 occ:1.00 SG D:CYS455 2.0 10.0 1.0 ND1 D:HIS473 2.0 10.0 1.0 SG D:CYS452 2.1 10.0 1.0 SG D:CYS476 2.1 10.0 1.0 H D:CYS455 2.9 10.0 1.0 H D:HIS473 2.9 10.0 1.0 CE1 D:HIS473 2.9 10.0 1.0 CG D:HIS473 3.1 10.0 1.0 HZ2 D:LYS479 3.3 10.0 1.0 CB D:CYS452 3.3 10.0 1.0 CB D:HIS473 3.5 10.0 1.0 N D:CYS455 3.6 10.0 1.0 CB D:CYS455 3.6 10.0 1.0 CB D:CYS476 3.7 10.0 1.0 N D:HIS473 3.7 10.0 1.0 H D:ILE454 3.9 10.0 1.0 CB D:ILE454 4.0 10.0 1.0 HZ1 D:LYS479 4.0 10.0 1.0 NE2 D:HIS473 4.1 10.0 1.0 NZ D:LYS479 4.1 10.0 1.0 CA D:CYS455 4.2 10.0 1.0 CD2 D:HIS473 4.2 10.0 1.0 CA D:HIS473 4.2 10.0 1.0 C D:ILE454 4.5 10.0 1.0 H D:CYS476 4.6 10.0 1.0 CA D:ILE454 4.6 10.0 1.0 HZ3 D:LYS479 4.6 10.0 1.0 N D:ILE454 4.6 10.0 1.0 CD2 D:LEU459 4.7 10.0 1.0 C D:PHE472 4.7 10.0 1.0 CA D:CYS452 4.7 10.0 1.0 CG1 D:ILE454 4.7 10.0 1.0 CG2 D:ILE454 4.7 10.0 1.0 CA D:PHE472 4.8 10.0 1.0 CA D:CYS476 4.9 10.0 1.0 H D:ASP453 4.9 10.0 1.0 C D:CYS455 4.9 10.0 1.0 O D:CYS455 4.9 10.0 1.0 HE2 D:HIS473 5.0 10.0 1.0

Zinc binding site 2 out of 2 in the uc(Nmr) Data-Driven Model of Kras-Gmppnp:Rbd-Crd Complex Tethered to A Nanodisc (State B)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of uc(Nmr) Data-Driven Model of Kras-Gmppnp:Rbd-Crd Complex Tethered to A Nanodisc (State B) within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn532 b:10.0 occ:1.00 SG D:CYS484 2.0 10.0 1.0 SG D:CYS465 2.1 10.0 1.0 SG D:CYS468 2.1 10.0 1.0 ND1 D:HIS439 2.2 10.0 1.0 CB D:CYS465 2.8 10.0 1.0 CB D:CYS468 2.8 10.0 1.0 CE1 D:HIS439 2.8 10.0 1.0 CB D:CYS484 3.1 10.0 1.0 H D:GLY469 3.3 10.0 1.0 CG D:HIS439 3.4 10.0 1.0 H D:TYR470 3.6 10.0 1.0 H D:CYS484 3.8 10.0 1.0 H D:CYS468 3.9 10.0 1.0 H D:ASN440 3.9 10.0 1.0 NE2 D:HIS439 4.1 10.0 1.0 CB D:HIS439 4.1 10.0 1.0 CA D:CYS468 4.1 10.0 1.0 CA D:CYS465 4.2 10.0 1.0 H D:CYS465 4.2 10.0 1.0 N D:GLY469 4.3 10.0 1.0 CA D:CYS484 4.3 10.0 1.0 CD2 D:HIS439 4.4 10.0 1.0 N D:CYS468 4.4 10.0 1.0 CA D:HIS439 4.4 10.0 1.0 N D:CYS484 4.4 10.0 1.0 CB D:TYR470 4.5 10.0 1.0 N D:TYR470 4.6 10.0 1.0 N D:CYS465 4.6 10.0 1.0 C D:CYS468 4.7 10.0 1.0 N D:ASN440 4.8 10.0 1.0 C D:CYS484 4.8 10.0 1.0 O D:CYS484 4.8 10.0 1.0 HE2 D:HIS439 4.8 10.0 1.0

Z.Fang, K.Lee, K.Huo, G.Gasmi-Seabrook, L.Zheng, N.Moghal, M.Tsao, M.Ikura, C.B.Marshall. Multivalent Assembly of Kras with the Ras-Binding and Cysteine-Rich Domains of Craf on the Membrane Proc.Natl.Acad.Sci.Usa 2020.
ISSN: ESSN 1091-6490
DOI: 10.1073/PNAS.1914076117