Zinc in PDB 6o19: Crystal Structure of PHO7 Complex with PHO1 Promoter Site 2

The structure of Crystal Structure of PHO7 Complex with PHO1 Promoter Site 2, PDB code: 6o19 was solved by A.Garg, Y.Goldgur, S.Shuman, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.57 / 1.60
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	53.169, 37.581, 57.564, 90.00, 104.23, 90.00
R / Rfree (%)	18.1 / 20.3

The binding sites of Zinc atom in the Crystal Structure of PHO7 Complex with PHO1 Promoter Site 2 (pdb code 6o19). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of PHO7 Complex with PHO1 Promoter Site 2, PDB code: 6o19:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of PHO7 Complex with PHO1 Promoter Site 2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of PHO7 Complex with PHO1 Promoter Site 2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:12.3 occ:1.00 SG A:CYS311 2.3 13.4 1.0 SG A:CYS318 2.3 11.1 1.0 SG A:CYS292 2.4 11.3 1.0 SG A:CYS308 2.4 10.8 1.0 CB A:CYS318 3.1 13.6 1.0 ZN A:ZN402 3.1 10.8 1.0 CB A:CYS311 3.2 12.7 1.0 CB A:CYS292 3.3 9.3 1.0 CB A:CYS308 3.6 11.4 1.0 CA A:CYS318 3.7 11.9 1.0 N A:CYS308 3.9 10.5 1.0 O A:HOH572 4.1 18.1 1.0 CA A:CYS308 4.3 10.9 1.0 N A:CYS311 4.3 12.1 1.0 CA A:CYS311 4.3 14.8 1.0 O A:HOH553 4.3 12.8 1.0 C A:CYS318 4.6 12.9 1.0 CA A:CYS292 4.7 10.7 1.0 O A:CYS308 4.8 12.5 1.0 SG A:CYS295 4.8 12.2 1.0 SG A:CYS302 4.8 10.3 1.0 N A:CYS318 4.8 11.7 1.0 C A:CYS308 4.8 12.6 1.0 N A:ILE319 5.0 12.8 1.0 O A:ASP317 5.0 14.9 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of PHO7 Complex with PHO1 Promoter Site 2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of PHO7 Complex with PHO1 Promoter Site 2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn402 b:10.8 occ:1.00 SG A:CYS302 2.3 10.3 1.0 SG A:CYS295 2.3 12.2 1.0 SG A:CYS308 2.4 10.8 1.0 SG A:CYS292 2.5 11.3 1.0 ZN A:ZN401 3.1 12.3 1.0 CB A:CYS302 3.2 10.6 1.0 CB A:CYS295 3.2 10.3 1.0 CB A:CYS308 3.3 11.4 1.0 CA A:CYS302 3.6 9.7 1.0 CB A:CYS292 3.6 9.3 1.0 N A:CYS292 4.0 10.5 1.0 O A:HOH572 4.0 18.1 1.0 O A:HOH538 4.2 13.1 1.0 N A:CYS295 4.3 11.4 1.0 CA A:CYS295 4.3 9.6 1.0 CA A:CYS292 4.4 10.7 1.0 N A:ASP303 4.6 10.4 1.0 N A:CYS302 4.7 11.1 1.0 C A:CYS302 4.7 10.8 1.0 SG A:CYS311 4.7 13.4 1.0 CA A:CYS308 4.8 10.9 1.0 SG A:CYS318 4.8 11.1 1.0 O A:CYS292 4.8 10.0 1.0 NH1 A:ARG306 4.8 12.2 1.0 C A:CYS292 4.9 9.9 1.0 CB A:ARG310 5.0 14.7 1.0

A.Garg, Y.Goldgur, A.M.Sanchez, B.Schwer, S.Shuman. Structure of Fission Yeast Transcription Factor PHO7 Bound TOPHO1PROMOTER Dna and Effect of PHO7 Mutations on Dna Binding and Phosphate Homeostasis. Mol.Cell.Biol. V. 39 2019.
ISSN: ESSN 1098-5549
PubMed: 31010807
DOI: 10.1128/MCB.00132-19