Zinc in PDB 6nzu: Structure of the Human Frataxin-Bound Iron-Sulfur Cluster Assembly Complex

All present enzymatic activity of Structure of the Human Frataxin-Bound Iron-Sulfur Cluster Assembly Complex:
1.16.3.1; 2.8.1.7;

The binding sites of Zinc atom in the Structure of the Human Frataxin-Bound Iron-Sulfur Cluster Assembly Complex (pdb code 6nzu). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of the Human Frataxin-Bound Iron-Sulfur Cluster Assembly Complex, PDB code: 6nzu:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of the Human Frataxin-Bound Iron-Sulfur Cluster Assembly Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of the Human Frataxin-Bound Iron-Sulfur Cluster Assembly Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn201 b:0.6 occ:1.00 OD1 D:ASP71 2.3 33.2 1.0 OD2 D:ASP71 2.3 33.2 1.0 CG D:ASP71 2.6 33.2 1.0 SG D:CYS95 2.8 28.5 1.0 SG D:CYS138 2.9 36.6 1.0 CB D:CYS95 3.4 28.5 1.0 O D:GLY70 3.8 31.2 1.0 N D:CYS95 3.9 28.5 1.0 CB D:ASP71 4.2 33.2 1.0 CA D:CYS95 4.3 28.5 1.0 OE2 A:GLU362 4.5 22.9 1.0 CB D:CYS138 4.5 36.6 1.0 C D:GLY70 4.6 31.2 1.0 NZ D:LYS135 4.7 33.6 1.0 CB D:ALA98 4.8 31.2 1.0 OE1 A:GLU362 4.8 22.9 1.0 CA D:ASP71 4.9 33.2 1.0 C D:GLY94 5.0 26.0 1.0

Zinc binding site 2 out of 2 in the Structure of the Human Frataxin-Bound Iron-Sulfur Cluster Assembly Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of the Human Frataxin-Bound Iron-Sulfur Cluster Assembly Complex within 5.0Å range: probe atom residue distance (Å) B Occ H:Zn201 b:98.4 occ:1.00 OD1 H:ASP71 2.3 33.4 1.0 OD2 H:ASP71 2.3 33.4 1.0 CG H:ASP71 2.6 33.4 1.0 SG H:CYS95 2.8 28.9 1.0 SG H:CYS138 2.9 37.3 1.0 CB H:CYS95 3.4 28.9 1.0 O H:GLY70 3.8 31.4 1.0 N H:CYS95 3.9 28.9 1.0 CB H:ASP71 4.2 33.4 1.0 CA H:CYS95 4.3 28.9 1.0 CB H:CYS138 4.5 37.3 1.0 OE2 E:GLU362 4.5 23.3 1.0 C H:GLY70 4.6 31.4 1.0 NZ H:LYS135 4.7 33.9 1.0 CB H:ALA98 4.8 32.0 1.0 OE1 E:GLU362 4.9 23.3 1.0 CA H:ASP71 4.9 33.4 1.0 C H:GLY94 5.0 26.2 1.0

N.G.Fox, X.Yu, X.Feng, H.J.Bailey, A.Martelli, J.F.Nabhan, C.Strain-Damerell, C.Bulawa, W.W.Yue, S.Han. Structure of the Human Frataxin-Bound Iron-Sulfur Cluster Assembly Complex Provides Insight Into Its Activation Mechanism. Nat Commun V. 10 2210 2019.
ISSN: ESSN 2041-1723
PubMed: 31101807
DOI: 10.1038/S41467-019-09989-Y