Zinc in PDB 6nur: Sars-Coronavirus NSP12 Bound to NSP7 and NSP8 Co-Factors

The binding sites of Zinc atom in the Sars-Coronavirus NSP12 Bound to NSP7 and NSP8 Co-Factors (pdb code 6nur). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Sars-Coronavirus NSP12 Bound to NSP7 and NSP8 Co-Factors, PDB code: 6nur:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Sars-Coronavirus NSP12 Bound to NSP7 and NSP8 Co-Factors


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Sars-Coronavirus NSP12 Bound to NSP7 and NSP8 Co-Factors within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:0.0 occ:1.00 SG A:CYS306 1.8 0.0 1.0 SG A:CYS301 2.0 1.0 1.0 ND1 A:HIS295 2.2 2.1 1.0 SG A:CYS310 2.8 0.2 1.0 CE1 A:HIS295 3.1 7.2 1.0 CB A:CYS301 3.2 5.0 1.0 CG A:HIS295 3.2 4.9 1.0 O A:CYS306 3.3 0.0 1.0 CB A:CYS306 3.4 0.9 1.0 CB A:HIS295 3.5 4.2 1.0 CA A:CYS301 3.6 6.8 1.0 C A:CYS306 4.0 1.2 1.0 CA A:CYS306 4.2 0.2 1.0 NE2 A:HIS295 4.2 4.9 1.0 CD2 A:HIS295 4.3 4.9 1.0 N A:HIS295 4.3 5.2 1.0 N A:CYS301 4.4 8.3 1.0 O A:THR293 4.4 9.1 1.0 CB A:CYS310 4.4 1.4 1.0 CA A:HIS295 4.5 2.0 1.0 O A:ASN300 4.7 9.3 1.0 C A:ASN300 4.8 6.2 1.0 C A:CYS301 4.8 10.4 1.0 N A:LEU302 4.9 8.9 1.0 O A:HIS295 4.9 4.0 1.0 N A:ILE307 5.0 0.9 1.0

Zinc binding site 2 out of 2 in the Sars-Coronavirus NSP12 Bound to NSP7 and NSP8 Co-Factors


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Sars-Coronavirus NSP12 Bound to NSP7 and NSP8 Co-Factors within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1002 b:33.4 occ:1.00 SG A:CYS645 2.1 16.6 1.0 O A:CYS645 2.3 0.0 1.0 SG A:CYS646 2.3 22.4 1.0 SG A:CYS487 2.4 25.6 1.0 ND1 A:HIS642 2.8 11.0 1.0 C A:CYS645 3.0 12.6 1.0 CB A:CYS646 3.1 12.4 1.0 CB A:CYS645 3.4 13.5 1.0 CB A:CYS487 3.4 12.3 1.0 CG A:HIS642 3.4 9.9 1.0 CB A:HIS642 3.5 12.4 1.0 N A:CYS646 3.7 14.1 1.0 CE1 A:HIS642 3.7 12.8 1.0 CA A:CYS645 3.8 12.3 1.0 CA A:CYS646 3.9 10.2 1.0 CA A:HIS642 4.2 11.4 1.0 N A:CYS487 4.2 13.6 1.0 CA A:CYS487 4.4 12.3 1.0 N A:CYS645 4.5 14.3 1.0 CD2 A:HIS642 4.5 7.9 1.0 NE2 A:HIS642 4.7 9.1 1.0 C A:HIS642 4.9 14.0 1.0

R.N.Kirchdoerfer, A.B.Ward. Structure of the Sars-Cov NSP12 Polymerase Bound to NSP7 and NSP8 Co-Factors. Nat Commun V. 10 2342 2019.
ISSN: ESSN 2041-1723
PubMed: 31138817
DOI: 10.1038/S41467-019-10280-3