Zinc in PDB 6nu9: Crystal Structure of A Zinc-Binding Non-Structural Protein From the Hepatitis E Virus

The structure of Crystal Structure of A Zinc-Binding Non-Structural Protein From the Hepatitis E Virus, PDB code: 6nu9 was solved by A.Proudfoot, D.Bussiere, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	52.62 / 1.76
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	64.399, 64.399, 158.901, 90.00, 90.00, 120.00
R / Rfree (%)	23.7 / 26.9

The binding sites of Zinc atom in the Crystal Structure of A Zinc-Binding Non-Structural Protein From the Hepatitis E Virus (pdb code 6nu9). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of A Zinc-Binding Non-Structural Protein From the Hepatitis E Virus, PDB code: 6nu9:

Zinc binding site 1 out of 1 in the Crystal Structure of A Zinc-Binding Non-Structural Protein From the Hepatitis E Virus


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of A Zinc-Binding Non-Structural Protein From the Hepatitis E Virus within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:21.3 occ:1.00 OE1 A:GLU166 1.9 20.2 1.0 ND1 A:HIS164 2.2 18.5 1.0 O A:HOH406 2.2 19.9 1.0 O A:HOH342 2.3 27.6 1.0 O A:HOH397 2.3 29.4 1.0 O A:HOH326 2.6 21.8 1.0 CD A:GLU166 2.8 16.3 1.0 OE2 A:GLU166 3.0 15.9 1.0 CE1 A:HIS164 3.1 17.6 1.0 CG A:HIS164 3.2 14.3 1.0 CB A:HIS164 3.6 8.6 1.0 OG A:SER176 3.7 16.1 0.4 O A:HIS179 4.0 32.5 1.0 CG A:GLU166 4.2 13.8 1.0 NE2 A:HIS164 4.3 17.1 1.0 OE1 A:GLU182 4.3 29.6 1.0 CD2 A:HIS164 4.3 15.7 1.0 O A:HOH470 4.4 24.2 1.0 O A:HOH359 4.4 34.2 1.0 CG2 A:THR67 4.5 14.9 1.0 O A:PRO177 4.7 25.5 1.0 CD1 A:PHE65 4.8 12.8 1.0 CA A:HIS164 5.0 7.2 1.0 O A:VAL180 5.0 35.5 1.0

A.Proudfoot, A.Hyrina, M.Holdorf, A.O.Frank, D.Bussiere. First Crystal Structure of A Nonstructural Hepatitis E Viral Protein Identifies A Putative Novel Zinc-Binding Protein. J.Virol. V. 93 2019.
ISSN: ESSN 1098-5514
PubMed: 31019049
DOI: 10.1128/JVI.00170-19