Zinc in PDB 6nm0: Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines
Enzymatic activity of Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines
All present enzymatic activity of Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines:
4.2.1.1;
4.2.1.1;
Protein crystallography data
The structure of Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines, PDB code: 6nm0
was solved by
S.Singh,
R.Mckenna,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 30.63 / 1.44 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 42.562, 41.529, 72.027, 90.00, 104.27, 90.00 |
| R / Rfree (%) | 16.6 / 18 |
Other elements in 6nm0:
The structure of Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines also contains other interesting chemical elements:
| Fluorine | (F) | 2 atoms |
Zinc Binding Sites:
The binding sites of Zinc atom in the Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines
(pdb code 6nm0). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines, PDB code: 6nm0:
In total only one binding site of Zinc was determined in the Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines, PDB code: 6nm0:
Zinc binding site 1 out of 1 in 6nm0
Go back to
Zinc Binding Sites List in 6nm0
Zinc binding site 1 out
of 1 in the Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines within 5.0Å range:
|
Reference:
S.Singh,
R.Mckenna,
M.Y.Mboge,
A.Wolff,
S.C.Clark,
T.Chingkuang,
C.T.Supuran,
Z.Zhang,
S.C.Frost.
Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines To Be Published.
Page generated: Wed Dec 16 12:24:07 2020
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