Zinc in PDB 6muu: Cryo-Em Structure of Csm-Crrna Binary Complex in Type III-A Crispr-Cas System

The binding sites of Zinc atom in the Cryo-Em Structure of Csm-Crrna Binary Complex in Type III-A Crispr-Cas System (pdb code 6muu). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Cryo-Em Structure of Csm-Crrna Binary Complex in Type III-A Crispr-Cas System, PDB code: 6muu:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Cryo-Em Structure of Csm-Crrna Binary Complex in Type III-A Crispr-Cas System


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Csm-Crrna Binary Complex in Type III-A Crispr-Cas System within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn801 b:49.6 occ:1.00 SG A:CYS413 2.4 38.5 1.0 SG A:CYS389 2.4 37.0 1.0 SG A:CYS392 2.5 35.0 1.0 CB A:CYS389 3.0 37.0 1.0 SG A:CYS416 3.1 32.9 1.0 CB A:CYS413 3.4 38.5 1.0 N A:CYS392 3.9 35.0 1.0 CB A:CYS392 3.9 35.0 1.0 CB A:CYS416 4.0 32.9 1.0 N A:CYS413 4.1 38.5 1.0 CG A:ARG394 4.3 35.3 1.0 CA A:CYS392 4.3 35.0 1.0 CA A:CYS413 4.4 38.5 1.0 CB A:ARG394 4.4 35.3 1.0 CA A:CYS389 4.5 37.0 1.0 O A:CYS392 4.5 35.0 1.0 C A:CYS392 4.6 35.0 1.0 CB A:VAL391 4.7 33.9 1.0 N A:ARG394 4.9 35.3 1.0 N A:CYS416 5.0 32.9 1.0 C A:VAL391 5.0 33.9 1.0

Zinc binding site 2 out of 3 in the Cryo-Em Structure of Csm-Crrna Binary Complex in Type III-A Crispr-Cas System


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of Csm-Crrna Binary Complex in Type III-A Crispr-Cas System within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn301 b:37.6 occ:1.00 NE2 C:HIS111 1.8 28.6 1.0 SG C:CYS122 2.0 29.0 1.0 SG C:CYS113 2.5 38.6 1.0 SG C:CYS125 2.5 28.1 1.0 CE1 C:HIS111 2.7 28.6 1.0 CD2 C:HIS111 2.8 28.6 1.0 CB C:CYS122 2.9 29.0 1.0 CB C:CYS125 3.1 28.1 1.0 N C:CYS125 3.7 28.1 1.0 ND1 C:HIS111 3.8 28.6 1.0 CB C:CYS113 3.9 38.6 1.0 CG C:HIS111 3.9 28.6 1.0 CA C:CYS125 4.1 28.1 1.0 N C:CYS113 4.3 38.6 1.0 CA C:CYS122 4.3 29.0 1.0 CB C:VAL124 4.4 26.9 1.0 CA C:CYS113 4.6 38.6 1.0 C C:VAL124 4.7 26.9 1.0 N C:VAL124 4.8 26.9 1.0 C C:CYS122 4.8 29.0 1.0 CA C:VAL124 4.9 26.9 1.0 CG1 C:VAL124 5.0 26.9 1.0

Zinc binding site 3 out of 3 in the Cryo-Em Structure of Csm-Crrna Binary Complex in Type III-A Crispr-Cas System


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Cryo-Em Structure of Csm-Crrna Binary Complex in Type III-A Crispr-Cas System within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn301 b:65.7 occ:1.00 SG D:CYS122 1.9 45.5 1.0 NE2 D:HIS111 2.5 41.5 1.0 CB D:CYS122 2.7 45.5 1.0 SG D:CYS125 2.7 38.5 1.0 SG D:CYS113 2.8 41.9 1.0 CB D:CYS125 3.1 38.5 1.0 N D:CYS125 3.3 38.5 1.0 CD2 D:HIS111 3.3 41.5 1.0 CE1 D:HIS111 3.5 41.5 1.0 CA D:CYS125 3.8 38.5 1.0 CB D:VAL124 3.8 42.0 1.0 CA D:CYS122 4.1 45.5 1.0 C D:VAL124 4.1 42.0 1.0 N D:VAL124 4.2 42.0 1.0 CA D:VAL124 4.3 42.0 1.0 CB D:CYS113 4.3 41.9 1.0 C D:CYS122 4.4 45.5 1.0 CG D:HIS111 4.5 41.5 1.0 ND1 D:HIS111 4.5 41.5 1.0 CG1 D:VAL124 4.6 42.0 1.0 N D:CYS113 4.6 41.9 1.0 CG2 D:VAL124 4.7 42.0 1.0 O D:CYS122 4.7 45.5 1.0 N D:PRO123 5.0 48.0 1.0 CA D:CYS113 5.0 41.9 1.0

N.Jia, C.Y.Mo, C.Wang, E.T.Eng, L.A.Marraffini, D.J.Patel. Type III-A Crispr-Cas Csm Complexes: Assembly, Periodic Rna Cleavage, Dnase Activity Regulation, and Autoimmunity. Mol. Cell V. 73 264 2019.
ISSN: ISSN 1097-4164
PubMed: 30503773
DOI: 10.1016/J.MOLCEL.2018.11.007