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Zinc in PDB 6mjx: Human Cgas Catalytic Domain Bound with CgampEnzymatic activity of Human Cgas Catalytic Domain Bound with Cgamp
All present enzymatic activity of Human Cgas Catalytic Domain Bound with Cgamp:
2.7.7.86; Protein crystallography data
The structure of Human Cgas Catalytic Domain Bound with Cgamp, PDB code: 6mjx
was solved by
L.Lama,
C.Adura,
W.Xie,
D.Tomita,
T.Kamei,
V.Kuryavyi,
T.Gogakos,
J.I.Steinberg,
M.Miller,
L.Ramos-Espiritu,
Y.Asano,
S.Hashizume,
J.Aida,
T.Imaeda,
R.Okamoto,
A.J.Jennings,
M.Michinom,
T.Kuroita,
A.Stamford,
P.Gao,
P.Meinke,
J.F.Glickman,
D.J.Patel,
T.Tuschl,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Human Cgas Catalytic Domain Bound with Cgamp
(pdb code 6mjx). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Human Cgas Catalytic Domain Bound with Cgamp, PDB code: 6mjx: Zinc binding site 1 out of 1 in 6mjxGo back to Zinc Binding Sites List in 6mjx
Zinc binding site 1 out
of 1 in the Human Cgas Catalytic Domain Bound with Cgamp
Mono view Stereo pair view
Reference:
L.Lama,
C.Adura,
W.Xie,
D.Tomita,
T.Kamei,
V.Kuryavyi,
T.Gogakos,
J.I.Steinberg,
M.Miller,
L.Ramos-Espiritu,
Y.Asano,
S.Hashizume,
J.Aida,
T.Imaeda,
R.Okamoto,
A.J.Jennings,
M.Michino,
T.Kuroita,
A.Stamford,
P.Gao,
P.Meinke,
J.F.Glickman,
D.J.Patel,
T.Tuschl.
Development of Human Cgas-Specific Small-Molecule Inhibitors For Repression of Dsdna-Triggered Interferon Expression. Nat Commun V. 10 2261 2019.
Page generated: Wed Dec 16 12:19:56 2020
ISSN: ESSN 2041-1723 PubMed: 31113940 DOI: 10.1038/S41467-019-08620-4 |
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