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Zinc in PDB 6mjw: Human Cgas Catalytic Domain Bound with the Inhibitor G150Enzymatic activity of Human Cgas Catalytic Domain Bound with the Inhibitor G150
All present enzymatic activity of Human Cgas Catalytic Domain Bound with the Inhibitor G150:
2.7.7.86; Protein crystallography data
The structure of Human Cgas Catalytic Domain Bound with the Inhibitor G150, PDB code: 6mjw
was solved by
L.Lama,
C.Adura,
W.Xie,
D.Tomita,
T.Kamei,
V.Kuryavyi,
T.Gogakos,
J.I.Steinberg,
M.Miller,
L.Ramos-Espiritu,
Y.Asano,
S.Hashizume,
J.Aida,
T.Imaeda,
R.Okamoto,
A.J.Jennings,
M.Michinom,
T.Kuroita,
A.Stamford,
P.Gao,
P.Meinke,
J.F.Glickman,
D.J.Patel,
T.Tuschl,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6mjw:
The structure of Human Cgas Catalytic Domain Bound with the Inhibitor G150 also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Human Cgas Catalytic Domain Bound with the Inhibitor G150
(pdb code 6mjw). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Human Cgas Catalytic Domain Bound with the Inhibitor G150, PDB code: 6mjw: Zinc binding site 1 out of 1 in 6mjwGo back to Zinc Binding Sites List in 6mjw
Zinc binding site 1 out
of 1 in the Human Cgas Catalytic Domain Bound with the Inhibitor G150
Mono view Stereo pair view
Reference:
L.Lama,
C.Adura,
W.Xie,
D.Tomita,
T.Kamei,
V.Kuryavyi,
T.Gogakos,
J.I.Steinberg,
M.Miller,
L.Ramos-Espiritu,
Y.Asano,
S.Hashizume,
J.Aida,
T.Imaeda,
R.Okamoto,
A.J.Jennings,
M.Michino,
T.Kuroita,
A.Stamford,
P.Gao,
P.Meinke,
J.F.Glickman,
D.J.Patel,
T.Tuschl.
Development of Human Cgas-Specific Small-Molecule Inhibitors For Repression of Dsdna-Triggered Interferon Expression. Nat Commun V. 10 2261 2019.
Page generated: Wed Dec 16 12:19:54 2020
ISSN: ESSN 2041-1723 PubMed: 31113940 DOI: 10.1038/S41467-019-08620-4 |
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