Zinc in PDB 6m2d: MUL1-Ring Domain
Enzymatic activity of MUL1-Ring Domain
All present enzymatic activity of MUL1-Ring Domain:
2.3.2.27;
Protein crystallography data
The structure of MUL1-Ring Domain, PDB code: 6m2d
was solved by
S.O.Lee,
K.S.Ryu,
S.-W.Chi,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
47.67 /
1.80
|
|
Space group
|
P 21 21 21
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
59.226,
66.593,
68.271,
90,
90,
90
|
|
R / Rfree (%)
|
17.2 /
22.7
|
Zinc Binding Sites:
Pages:
>>> Page 1 <<<
Page 2, Binding sites: 11 -
12;
Binding sites:
The binding sites of Zinc atom in the MUL1-Ring Domain
(pdb code 6m2d). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 12 binding sites of Zinc where determined in the
MUL1-Ring Domain, PDB code: 6m2d:
Jump to Zinc binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Zinc binding site 1 out
of 12 in 6m2d
Go back to
Zinc Binding Sites List in 6m2d
Zinc binding site 1 out
of 12 in the MUL1-Ring Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of MUL1-Ring Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn401
b:25.4
occ:1.00
|
SG
|
A:CYS326
|
2.3
|
17.7
|
1.0
|
|
SG
|
A:CYS323
|
2.4
|
17.7
|
1.0
|
|
SG
|
A:CYS302
|
2.4
|
16.7
|
1.0
|
|
SG
|
A:CYS305
|
2.4
|
17.0
|
1.0
|
|
HB2
|
A:CYS326
|
2.8
|
19.7
|
1.0
|
|
H
|
A:CYS305
|
2.9
|
18.4
|
1.0
|
|
HB3
|
A:CYS305
|
3.0
|
18.3
|
1.0
|
|
HB3
|
A:CYS302
|
3.0
|
16.5
|
1.0
|
|
CB
|
A:CYS326
|
3.1
|
19.7
|
1.0
|
|
CB
|
A:CYS302
|
3.2
|
16.5
|
1.0
|
|
H
|
A:CYS323
|
3.2
|
12.4
|
1.0
|
|
CB
|
A:CYS305
|
3.3
|
18.3
|
1.0
|
|
HB2
|
A:CYS302
|
3.4
|
16.5
|
1.0
|
|
HB3
|
A:CYS323
|
3.5
|
15.6
|
1.0
|
|
HB
|
A:VAL304
|
3.6
|
21.2
|
1.0
|
|
CB
|
A:CYS323
|
3.6
|
15.6
|
1.0
|
|
N
|
A:CYS305
|
3.6
|
18.4
|
1.0
|
|
H
|
A:CYS326
|
3.7
|
18.0
|
1.0
|
|
HB3
|
A:CYS326
|
3.7
|
19.7
|
1.0
|
|
HB2
|
A:SER308
|
3.8
|
15.9
|
1.0
|
|
N
|
A:CYS323
|
4.0
|
12.4
|
1.0
|
|
CA
|
A:CYS305
|
4.1
|
17.2
|
1.0
|
|
HB2
|
A:CYS305
|
4.1
|
18.3
|
1.0
|
|
H
|
A:SER308
|
4.1
|
16.3
|
1.0
|
|
O
|
A:HOH548
|
4.2
|
28.0
|
1.0
|
|
N
|
A:CYS326
|
4.2
|
18.0
|
1.0
|
|
CA
|
A:CYS326
|
4.2
|
17.6
|
1.0
|
|
CA
|
A:CYS323
|
4.3
|
15.5
|
1.0
|
|
H
|
A:VAL304
|
4.3
|
17.6
|
1.0
|
|
HB2
|
A:CYS323
|
4.4
|
15.6
|
1.0
|
|
O
|
A:HOH528
|
4.5
|
28.1
|
1.0
|
|
H
|
A:LEU306
|
4.5
|
19.2
|
1.0
|
|
CB
|
A:VAL304
|
4.5
|
21.2
|
1.0
|
|
H
|
A:SER307
|
4.6
|
20.8
|
1.0
|
|
HA
|
A:CYS326
|
4.6
|
17.6
|
1.0
|
|
CA
|
A:CYS302
|
4.6
|
18.9
|
1.0
|
|
HA
|
A:SER322
|
4.7
|
14.8
|
1.0
|
|
CB
|
A:SER308
|
4.7
|
15.9
|
1.0
|
|
C
|
A:VAL304
|
4.7
|
20.4
|
1.0
|
|
O
|
A:HOH527
|
4.7
|
30.1
|
1.0
|
|
HA
|
A:CYS305
|
4.8
|
17.2
|
1.0
|
|
C
|
A:CYS323
|
4.8
|
15.8
|
1.0
|
|
O
|
A:CYS323
|
4.8
|
18.1
|
1.0
|
|
OG
|
A:SER322
|
4.9
|
16.4
|
1.0
|
|
N
|
A:SER308
|
4.9
|
16.3
|
1.0
|
|
C
|
A:CYS305
|
4.9
|
18.8
|
1.0
|
|
N
|
A:LEU306
|
4.9
|
19.2
|
1.0
|
|
CA
|
A:VAL304
|
5.0
|
14.3
|
1.0
|
|
N
|
A:VAL304
|
5.0
|
17.6
|
1.0
|
|
HG12
|
A:VAL304
|
5.0
|
23.3
|
1.0
|
|
Zinc binding site 2 out
of 12 in 6m2d
Go back to
Zinc Binding Sites List in 6m2d
Zinc binding site 2 out
of 12 in the MUL1-Ring Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of MUL1-Ring Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn402
b:28.0
occ:1.00
|
ND1
|
A:HIS319
|
2.1
|
21.0
|
1.0
|
|
SG
|
A:CYS336
|
2.3
|
17.9
|
1.0
|
|
SG
|
A:CYS317
|
2.4
|
19.1
|
1.0
|
|
SG
|
A:CYS339
|
2.4
|
19.6
|
1.0
|
|
HB2
|
A:HIS319
|
2.8
|
21.2
|
1.0
|
|
HB2
|
A:CYS317
|
2.9
|
23.3
|
1.0
|
|
HB3
|
A:CYS336
|
2.9
|
20.8
|
1.0
|
|
CB
|
A:CYS336
|
3.0
|
20.8
|
1.0
|
|
CG
|
A:HIS319
|
3.1
|
21.0
|
1.0
|
|
CE1
|
A:HIS319
|
3.1
|
22.7
|
1.0
|
|
H
|
A:CYS339
|
3.1
|
18.2
|
1.0
|
|
HB2
|
A:CYS336
|
3.1
|
20.8
|
1.0
|
|
CB
|
A:CYS317
|
3.2
|
23.3
|
1.0
|
|
HB3
|
A:CYS339
|
3.2
|
20.2
|
1.0
|
|
HE1
|
A:HIS319
|
3.3
|
22.7
|
1.0
|
|
CB
|
A:HIS319
|
3.4
|
21.2
|
1.0
|
|
HB
|
A:ILE338
|
3.4
|
22.3
|
1.0
|
|
CB
|
A:CYS339
|
3.4
|
20.2
|
1.0
|
|
HB3
|
A:CYS317
|
3.5
|
23.3
|
1.0
|
|
N
|
A:CYS339
|
3.7
|
18.2
|
1.0
|
|
H
|
A:HIS319
|
3.8
|
18.4
|
1.0
|
|
HB3
|
A:HIS319
|
3.9
|
21.2
|
1.0
|
|
CA
|
A:CYS339
|
4.2
|
21.4
|
1.0
|
|
NE2
|
A:HIS319
|
4.2
|
25.2
|
1.0
|
|
HB2
|
A:GLN341
|
4.2
|
29.8
|
1.0
|
|
CD2
|
A:HIS319
|
4.2
|
24.7
|
1.0
|
|
HB2
|
A:CYS339
|
4.2
|
20.2
|
1.0
|
|
H
|
A:ILE338
|
4.2
|
20.7
|
1.0
|
|
CB
|
A:ILE338
|
4.3
|
22.3
|
1.0
|
|
H
|
A:GLN341
|
4.4
|
21.7
|
1.0
|
|
N
|
A:HIS319
|
4.5
|
18.4
|
1.0
|
|
CA
|
A:CYS336
|
4.5
|
16.9
|
1.0
|
|
CA
|
A:CYS317
|
4.5
|
23.3
|
1.0
|
|
CA
|
A:HIS319
|
4.5
|
19.6
|
1.0
|
|
HD2
|
A:PHE314
|
4.6
|
17.5
|
1.0
|
|
H
|
A:ARG340
|
4.6
|
18.5
|
1.0
|
|
HB2
|
A:PHE314
|
4.6
|
20.5
|
1.0
|
|
HG22
|
A:ILE338
|
4.7
|
16.4
|
1.0
|
|
C
|
A:ILE338
|
4.7
|
23.2
|
1.0
|
|
C
|
A:CYS317
|
4.8
|
19.8
|
1.0
|
|
N
|
A:ILE338
|
4.9
|
20.7
|
1.0
|
|
C
|
A:CYS339
|
4.9
|
21.1
|
1.0
|
|
CA
|
A:ILE338
|
4.9
|
18.8
|
1.0
|
|
HA
|
A:CYS336
|
4.9
|
16.9
|
1.0
|
|
O
|
A:HOH524
|
4.9
|
31.1
|
1.0
|
|
N
|
A:ARG340
|
5.0
|
18.5
|
1.0
|
|
CG2
|
A:ILE338
|
5.0
|
16.4
|
1.0
|
|
HE2
|
A:HIS319
|
5.0
|
25.2
|
1.0
|
|
HG21
|
A:ILE338
|
5.0
|
16.4
|
1.0
|
|
HA
|
A:CYS339
|
5.0
|
21.4
|
1.0
|
|
C
|
A:CYS336
|
5.0
|
22.3
|
1.0
|
|
Zinc binding site 3 out
of 12 in 6m2d
Go back to
Zinc Binding Sites List in 6m2d
Zinc binding site 3 out
of 12 in the MUL1-Ring Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of MUL1-Ring Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn401
b:26.2
occ:1.00
|
SG
|
B:CYS326
|
2.4
|
17.8
|
1.0
|
|
SG
|
B:CYS323
|
2.4
|
15.4
|
1.0
|
|
SG
|
B:CYS302
|
2.4
|
16.1
|
1.0
|
|
SG
|
B:CYS305
|
2.4
|
19.5
|
1.0
|
|
H
|
B:CYS305
|
2.8
|
17.7
|
1.0
|
|
HB2
|
B:CYS326
|
2.8
|
16.3
|
1.0
|
|
HB3
|
B:CYS305
|
2.9
|
22.0
|
1.0
|
|
HB3
|
B:CYS302
|
2.9
|
13.2
|
1.0
|
|
H
|
B:CYS323
|
3.1
|
11.9
|
1.0
|
|
CB
|
B:CYS302
|
3.1
|
13.2
|
1.0
|
|
CB
|
B:CYS326
|
3.2
|
16.3
|
1.0
|
|
CB
|
B:CYS305
|
3.2
|
22.0
|
1.0
|
|
HB2
|
B:CYS302
|
3.3
|
13.2
|
1.0
|
|
HB3
|
B:CYS323
|
3.4
|
16.1
|
1.0
|
|
CB
|
B:CYS323
|
3.5
|
16.1
|
1.0
|
|
N
|
B:CYS305
|
3.5
|
17.7
|
1.0
|
|
HB2
|
B:SER308
|
3.6
|
18.8
|
1.0
|
|
HB
|
B:VAL304
|
3.6
|
15.5
|
1.0
|
|
H
|
B:CYS326
|
3.7
|
17.9
|
1.0
|
|
HB3
|
B:CYS326
|
3.7
|
16.3
|
1.0
|
|
O
|
B:HOH543
|
3.8
|
30.8
|
1.0
|
|
N
|
B:CYS323
|
3.9
|
11.9
|
1.0
|
|
CA
|
B:CYS305
|
3.9
|
16.9
|
1.0
|
|
HB2
|
B:CYS305
|
4.0
|
22.0
|
1.0
|
|
O
|
C:HOH547
|
4.1
|
25.4
|
1.0
|
|
H
|
B:VAL304
|
4.2
|
14.6
|
1.0
|
|
CA
|
B:CYS323
|
4.3
|
14.8
|
1.0
|
|
N
|
B:CYS326
|
4.3
|
17.9
|
1.0
|
|
HB2
|
B:CYS323
|
4.3
|
16.1
|
1.0
|
|
CA
|
B:CYS326
|
4.3
|
17.2
|
1.0
|
|
H
|
B:SER308
|
4.3
|
19.9
|
1.0
|
|
CB
|
B:VAL304
|
4.5
|
15.5
|
1.0
|
|
CB
|
B:SER308
|
4.5
|
18.8
|
1.0
|
|
H
|
B:LEU306
|
4.6
|
18.5
|
1.0
|
|
CA
|
B:CYS302
|
4.6
|
15.1
|
1.0
|
|
HA
|
B:SER322
|
4.6
|
14.8
|
1.0
|
|
C
|
B:VAL304
|
4.6
|
18.5
|
1.0
|
|
HA
|
B:CYS305
|
4.7
|
16.9
|
1.0
|
|
HA
|
B:CYS326
|
4.7
|
17.2
|
1.0
|
|
HG12
|
B:VAL304
|
4.8
|
20.3
|
1.0
|
|
OG
|
B:SER322
|
4.8
|
15.3
|
1.0
|
|
H
|
B:SER307
|
4.8
|
16.3
|
1.0
|
|
C
|
B:CYS305
|
4.9
|
20.9
|
1.0
|
|
C
|
B:CYS323
|
4.9
|
16.2
|
1.0
|
|
N
|
B:VAL304
|
4.9
|
14.6
|
1.0
|
|
HB3
|
B:SER308
|
4.9
|
18.8
|
1.0
|
|
CA
|
B:VAL304
|
4.9
|
15.3
|
1.0
|
|
C
|
B:CYS302
|
5.0
|
17.5
|
1.0
|
|
N
|
B:LEU306
|
5.0
|
18.5
|
1.0
|
|
Zinc binding site 4 out
of 12 in 6m2d
Go back to
Zinc Binding Sites List in 6m2d
Zinc binding site 4 out
of 12 in the MUL1-Ring Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of MUL1-Ring Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn402
b:27.7
occ:1.00
|
ND1
|
B:HIS319
|
2.1
|
16.9
|
1.0
|
|
SG
|
B:CYS336
|
2.3
|
18.0
|
1.0
|
|
SG
|
B:CYS339
|
2.4
|
21.8
|
1.0
|
|
SG
|
B:CYS317
|
2.4
|
14.7
|
1.0
|
|
HB2
|
B:HIS319
|
2.8
|
15.0
|
1.0
|
|
HB2
|
B:CYS317
|
2.9
|
19.5
|
1.0
|
|
H
|
B:CYS339
|
2.9
|
20.3
|
1.0
|
|
HB3
|
B:CYS336
|
3.0
|
19.4
|
1.0
|
|
CB
|
B:CYS317
|
3.1
|
19.5
|
1.0
|
|
CB
|
B:CYS336
|
3.1
|
19.4
|
1.0
|
|
CG
|
B:HIS319
|
3.1
|
19.2
|
1.0
|
|
CE1
|
B:HIS319
|
3.1
|
19.5
|
1.0
|
|
HB2
|
B:CYS336
|
3.2
|
19.4
|
1.0
|
|
HE1
|
B:HIS319
|
3.3
|
19.5
|
1.0
|
|
HB3
|
B:CYS317
|
3.3
|
19.5
|
1.0
|
|
HB
|
B:ILE338
|
3.4
|
24.2
|
1.0
|
|
CB
|
B:HIS319
|
3.4
|
15.0
|
1.0
|
|
HB3
|
B:CYS339
|
3.4
|
24.9
|
1.0
|
|
CB
|
B:CYS339
|
3.5
|
24.9
|
1.0
|
|
N
|
B:CYS339
|
3.7
|
20.3
|
1.0
|
|
H
|
B:HIS319
|
3.8
|
17.7
|
1.0
|
|
HB3
|
B:HIS319
|
3.9
|
15.0
|
1.0
|
|
CA
|
B:CYS339
|
4.1
|
21.7
|
1.0
|
|
NE2
|
B:HIS319
|
4.2
|
21.3
|
1.0
|
|
CD2
|
B:HIS319
|
4.2
|
23.6
|
1.0
|
|
H
|
B:ILE338
|
4.2
|
19.8
|
1.0
|
|
H
|
B:ARG340
|
4.3
|
22.1
|
1.0
|
|
HB2
|
B:CYS339
|
4.3
|
24.9
|
1.0
|
|
CB
|
B:ILE338
|
4.3
|
24.2
|
1.0
|
|
N
|
B:HIS319
|
4.5
|
17.7
|
1.0
|
|
CA
|
B:CYS317
|
4.5
|
17.9
|
1.0
|
|
H
|
B:GLN341
|
4.5
|
22.5
|
1.0
|
|
CA
|
B:CYS336
|
4.6
|
19.5
|
1.0
|
|
CA
|
B:HIS319
|
4.6
|
16.7
|
1.0
|
|
HB2
|
B:PHE314
|
4.6
|
16.3
|
1.0
|
|
O
|
B:HOH504
|
4.6
|
35.1
|
1.0
|
|
HB2
|
B:GLN341
|
4.7
|
27.8
|
1.0
|
|
C
|
B:ILE338
|
4.7
|
23.0
|
1.0
|
|
N
|
B:ARG340
|
4.7
|
22.1
|
1.0
|
|
O
|
B:HOH517
|
4.7
|
17.8
|
1.0
|
|
HD2
|
B:PHE314
|
4.8
|
13.8
|
1.0
|
|
C
|
B:CYS339
|
4.8
|
22.3
|
1.0
|
|
HG13
|
B:ILE338
|
4.8
|
24.1
|
1.0
|
|
C
|
B:CYS317
|
4.9
|
20.0
|
1.0
|
|
N
|
B:ILE338
|
4.9
|
19.8
|
1.0
|
|
H
|
B:CYS317
|
4.9
|
17.1
|
1.0
|
|
CA
|
B:ILE338
|
4.9
|
21.3
|
1.0
|
|
HG12
|
B:ILE338
|
4.9
|
24.1
|
1.0
|
|
HA
|
B:CYS339
|
5.0
|
21.7
|
1.0
|
|
HA
|
B:CYS336
|
5.0
|
19.5
|
1.0
|
|
CG1
|
B:ILE338
|
5.0
|
24.1
|
1.0
|
|
Zinc binding site 5 out
of 12 in 6m2d
Go back to
Zinc Binding Sites List in 6m2d
Zinc binding site 5 out
of 12 in the MUL1-Ring Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of MUL1-Ring Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn401
b:27.2
occ:1.00
|
SG
|
C:CYS326
|
2.3
|
17.9
|
1.0
|
|
SG
|
C:CYS323
|
2.4
|
16.7
|
1.0
|
|
SG
|
C:CYS302
|
2.4
|
14.7
|
1.0
|
|
SG
|
C:CYS305
|
2.4
|
17.9
|
1.0
|
|
HB2
|
C:CYS326
|
2.8
|
16.4
|
1.0
|
|
H
|
C:CYS305
|
2.9
|
18.9
|
1.0
|
|
HB3
|
C:CYS302
|
3.0
|
16.1
|
1.0
|
|
HB3
|
C:CYS305
|
3.0
|
20.9
|
1.0
|
|
CB
|
C:CYS326
|
3.1
|
16.4
|
1.0
|
|
CB
|
C:CYS302
|
3.1
|
16.1
|
1.0
|
|
H
|
C:CYS323
|
3.2
|
14.4
|
1.0
|
|
CB
|
C:CYS305
|
3.3
|
20.9
|
1.0
|
|
HB2
|
C:CYS302
|
3.3
|
16.1
|
1.0
|
|
HB3
|
C:CYS323
|
3.4
|
17.9
|
1.0
|
|
HB2
|
C:SER308
|
3.4
|
18.6
|
1.0
|
|
CB
|
C:CYS323
|
3.5
|
17.9
|
1.0
|
|
HB
|
C:VAL304
|
3.6
|
15.8
|
1.0
|
|
HB3
|
C:CYS326
|
3.6
|
16.4
|
1.0
|
|
H
|
C:CYS326
|
3.7
|
13.8
|
1.0
|
|
N
|
C:CYS305
|
3.7
|
18.9
|
1.0
|
|
N
|
C:CYS323
|
4.0
|
14.4
|
1.0
|
|
HB2
|
C:CYS305
|
4.1
|
20.9
|
1.0
|
|
CA
|
C:CYS305
|
4.1
|
19.9
|
1.0
|
|
N
|
C:CYS326
|
4.2
|
13.8
|
1.0
|
|
CA
|
C:CYS326
|
4.3
|
16.2
|
1.0
|
|
HB2
|
C:CYS323
|
4.3
|
17.9
|
1.0
|
|
CA
|
C:CYS323
|
4.3
|
17.5
|
1.0
|
|
H
|
C:SER308
|
4.3
|
18.6
|
1.0
|
|
H
|
C:VAL304
|
4.4
|
18.9
|
1.0
|
|
CB
|
C:SER308
|
4.4
|
18.6
|
1.0
|
|
H
|
C:LEU306
|
4.4
|
18.2
|
1.0
|
|
O
|
C:HOH530
|
4.5
|
25.5
|
1.0
|
|
CB
|
C:VAL304
|
4.6
|
15.8
|
1.0
|
|
CA
|
C:CYS302
|
4.6
|
15.0
|
1.0
|
|
HA
|
C:CYS326
|
4.7
|
16.2
|
1.0
|
|
HA
|
C:SER322
|
4.8
|
15.0
|
1.0
|
|
HB3
|
C:SER308
|
4.8
|
18.6
|
1.0
|
|
C
|
C:VAL304
|
4.8
|
19.8
|
1.0
|
|
HA
|
C:CYS305
|
4.9
|
19.9
|
1.0
|
|
N
|
C:LEU306
|
4.9
|
18.2
|
1.0
|
|
HG12
|
C:VAL304
|
4.9
|
18.9
|
1.0
|
|
C
|
C:CYS323
|
4.9
|
15.7
|
1.0
|
|
OG
|
C:SER308
|
4.9
|
17.8
|
1.0
|
|
C
|
C:CYS305
|
4.9
|
21.2
|
1.0
|
|
Zinc binding site 6 out
of 12 in 6m2d
Go back to
Zinc Binding Sites List in 6m2d
Zinc binding site 6 out
of 12 in the MUL1-Ring Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of MUL1-Ring Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn402
b:31.9
occ:1.00
|
ND1
|
C:HIS319
|
2.1
|
22.1
|
1.0
|
|
SG
|
C:CYS339
|
2.3
|
20.8
|
1.0
|
|
SG
|
C:CYS336
|
2.4
|
20.4
|
1.0
|
|
SG
|
C:CYS317
|
2.4
|
20.4
|
1.0
|
|
HB2
|
C:CYS317
|
2.8
|
19.3
|
1.0
|
|
HB2
|
C:HIS319
|
2.8
|
19.3
|
1.0
|
|
HB3
|
C:CYS336
|
3.0
|
22.7
|
1.0
|
|
CB
|
C:CYS317
|
3.0
|
19.3
|
1.0
|
|
CB
|
C:CYS336
|
3.0
|
22.7
|
1.0
|
|
HB2
|
C:CYS336
|
3.1
|
22.7
|
1.0
|
|
CE1
|
C:HIS319
|
3.1
|
25.7
|
1.0
|
|
CG
|
C:HIS319
|
3.1
|
18.5
|
1.0
|
|
HB3
|
C:CYS339
|
3.2
|
26.2
|
1.0
|
|
HE1
|
C:HIS319
|
3.2
|
25.7
|
1.0
|
|
H
|
C:CYS339
|
3.3
|
24.0
|
1.0
|
|
HB3
|
C:CYS317
|
3.3
|
19.3
|
1.0
|
|
CB
|
C:CYS339
|
3.3
|
26.2
|
1.0
|
|
CB
|
C:HIS319
|
3.5
|
19.3
|
1.0
|
|
HB
|
C:ILE338
|
3.6
|
22.9
|
1.0
|
|
H
|
C:HIS319
|
3.7
|
16.8
|
1.0
|
|
N
|
C:CYS339
|
3.8
|
24.0
|
1.0
|
|
HB3
|
C:HIS319
|
4.0
|
19.3
|
1.0
|
|
HB2
|
C:CYS339
|
4.1
|
26.2
|
1.0
|
|
CA
|
C:CYS339
|
4.1
|
27.2
|
1.0
|
|
NE2
|
C:HIS319
|
4.2
|
25.9
|
1.0
|
|
CD2
|
C:HIS319
|
4.2
|
22.6
|
1.0
|
|
H
|
C:ILE338
|
4.3
|
28.1
|
1.0
|
|
HB3
|
C:GLN341
|
4.4
|
29.2
|
1.0
|
|
H
|
C:GLN341
|
4.4
|
24.9
|
1.0
|
|
N
|
C:HIS319
|
4.4
|
16.8
|
1.0
|
|
CA
|
C:CYS317
|
4.4
|
18.6
|
1.0
|
|
CB
|
C:ILE338
|
4.5
|
22.9
|
1.0
|
|
CA
|
C:CYS336
|
4.5
|
24.7
|
1.0
|
|
CA
|
C:HIS319
|
4.6
|
19.2
|
1.0
|
|
O
|
C:HOH544
|
4.6
|
32.9
|
1.0
|
|
HB2
|
C:PHE314
|
4.7
|
18.6
|
1.0
|
|
C
|
C:CYS317
|
4.7
|
22.3
|
1.0
|
|
C
|
C:ILE338
|
4.8
|
26.6
|
1.0
|
|
C
|
C:CYS339
|
4.8
|
30.1
|
1.0
|
|
H
|
C:ARG340
|
4.8
|
26.8
|
1.0
|
|
HD2
|
C:PHE314
|
4.8
|
18.4
|
1.0
|
|
O
|
C:HOH525
|
4.9
|
26.0
|
1.0
|
|
HA
|
C:CYS336
|
4.9
|
24.7
|
1.0
|
|
HB2
|
C:GLN341
|
4.9
|
29.2
|
1.0
|
|
N
|
C:ILE338
|
4.9
|
28.1
|
1.0
|
|
H
|
C:CYS317
|
5.0
|
23.0
|
1.0
|
|
HE2
|
C:HIS319
|
5.0
|
25.9
|
1.0
|
|
CA
|
C:ILE338
|
5.0
|
26.5
|
1.0
|
|
HA
|
C:CYS339
|
5.0
|
27.2
|
1.0
|
|
HA
|
C:CYS317
|
5.0
|
18.6
|
1.0
|
|
Zinc binding site 7 out
of 12 in 6m2d
Go back to
Zinc Binding Sites List in 6m2d
Zinc binding site 7 out
of 12 in the MUL1-Ring Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 7 of MUL1-Ring Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Zn401
b:28.7
occ:1.00
|
SG
|
D:CYS326
|
2.3
|
19.5
|
1.0
|
|
SG
|
D:CYS305
|
2.4
|
20.1
|
1.0
|
|
SG
|
D:CYS302
|
2.4
|
16.9
|
1.0
|
|
SG
|
D:CYS323
|
2.4
|
17.4
|
1.0
|
|
HB2
|
D:CYS326
|
2.9
|
19.7
|
1.0
|
|
HB3
|
D:CYS302
|
3.0
|
18.5
|
1.0
|
|
HB3
|
D:CYS305
|
3.0
|
25.0
|
1.0
|
|
H
|
D:CYS305
|
3.1
|
21.3
|
1.0
|
|
CB
|
D:CYS302
|
3.2
|
18.5
|
1.0
|
|
CB
|
D:CYS326
|
3.2
|
19.7
|
1.0
|
|
H
|
D:CYS323
|
3.3
|
15.6
|
1.0
|
|
CB
|
D:CYS305
|
3.3
|
25.0
|
1.0
|
|
HB2
|
D:CYS302
|
3.3
|
18.5
|
1.0
|
|
HB3
|
D:CYS323
|
3.5
|
14.9
|
1.0
|
|
HB2
|
D:SER308
|
3.6
|
19.1
|
1.0
|
|
CB
|
D:CYS323
|
3.6
|
14.9
|
1.0
|
|
HB
|
D:VAL304
|
3.7
|
17.8
|
1.0
|
|
HB3
|
D:CYS326
|
3.7
|
19.7
|
1.0
|
|
N
|
D:CYS305
|
3.7
|
21.3
|
1.0
|
|
H
|
D:CYS326
|
3.9
|
17.1
|
1.0
|
|
N
|
D:CYS323
|
4.0
|
15.6
|
1.0
|
|
HB2
|
D:CYS305
|
4.1
|
25.0
|
1.0
|
|
CA
|
D:CYS305
|
4.1
|
22.3
|
1.0
|
|
H
|
D:VAL304
|
4.4
|
18.1
|
1.0
|
|
HB2
|
D:CYS323
|
4.4
|
14.9
|
1.0
|
|
CA
|
D:CYS323
|
4.4
|
18.0
|
1.0
|
|
CA
|
D:CYS326
|
4.4
|
15.7
|
1.0
|
|
CB
|
D:SER308
|
4.4
|
19.1
|
1.0
|
|
N
|
D:CYS326
|
4.4
|
17.1
|
1.0
|
|
OG
|
D:SER308
|
4.4
|
18.9
|
1.0
|
|
H
|
D:SER308
|
4.5
|
19.5
|
1.0
|
|
CB
|
D:VAL304
|
4.6
|
17.8
|
1.0
|
|
CA
|
D:CYS302
|
4.6
|
16.9
|
1.0
|
|
H
|
D:SER307
|
4.7
|
23.0
|
1.0
|
|
H
|
D:LEU306
|
4.7
|
20.9
|
1.0
|
|
C
|
D:VAL304
|
4.7
|
24.7
|
1.0
|
|
HA
|
D:CYS326
|
4.8
|
15.7
|
1.0
|
|
HG
|
D:SER322
|
4.8
|
21.5
|
1.0
|
|
HG12
|
D:VAL304
|
4.8
|
21.7
|
1.0
|
|
HA
|
D:SER322
|
4.8
|
17.4
|
1.0
|
|
HA
|
D:CYS305
|
4.9
|
22.3
|
1.0
|
|
OG
|
D:SER322
|
4.9
|
21.5
|
1.0
|
|
O
|
D:CYS323
|
4.9
|
16.2
|
1.0
|
|
HG
|
D:SER308
|
4.9
|
18.9
|
1.0
|
|
C
|
D:CYS323
|
4.9
|
15.2
|
1.0
|
|
C
|
D:CYS305
|
4.9
|
23.2
|
1.0
|
|
N
|
D:VAL304
|
5.0
|
18.1
|
1.0
|
|
N
|
D:SER308
|
5.0
|
19.5
|
1.0
|
|
C
|
D:CYS302
|
5.0
|
15.8
|
1.0
|
|
CA
|
D:VAL304
|
5.0
|
20.7
|
1.0
|
|
Zinc binding site 8 out
of 12 in 6m2d
Go back to
Zinc Binding Sites List in 6m2d
Zinc binding site 8 out
of 12 in the MUL1-Ring Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 8 of MUL1-Ring Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Zn402
b:27.4
occ:1.00
|
ND1
|
D:HIS319
|
2.1
|
18.8
|
1.0
|
|
SG
|
D:CYS336
|
2.3
|
20.2
|
1.0
|
|
SG
|
D:CYS339
|
2.4
|
19.2
|
1.0
|
|
SG
|
D:CYS317
|
2.4
|
18.1
|
1.0
|
|
HB2
|
D:HIS319
|
2.8
|
18.4
|
1.0
|
|
HB2
|
D:CYS317
|
2.9
|
21.2
|
1.0
|
|
HB3
|
D:CYS336
|
3.0
|
20.1
|
1.0
|
|
CE1
|
D:HIS319
|
3.0
|
27.2
|
1.0
|
|
CB
|
D:CYS336
|
3.0
|
20.1
|
1.0
|
|
H
|
D:CYS339
|
3.1
|
24.9
|
1.0
|
|
CG
|
D:HIS319
|
3.1
|
22.7
|
1.0
|
|
HB2
|
D:CYS336
|
3.1
|
20.1
|
1.0
|
|
CB
|
D:CYS317
|
3.2
|
21.2
|
1.0
|
|
HE1
|
D:HIS319
|
3.2
|
27.2
|
1.0
|
|
HB
|
D:ILE338
|
3.3
|
23.3
|
1.0
|
|
HB3
|
D:CYS339
|
3.3
|
20.0
|
1.0
|
|
HB3
|
D:CYS317
|
3.4
|
21.2
|
1.0
|
|
CB
|
D:HIS319
|
3.4
|
18.4
|
1.0
|
|
CB
|
D:CYS339
|
3.4
|
20.0
|
1.0
|
|
N
|
D:CYS339
|
3.7
|
24.9
|
1.0
|
|
H
|
D:HIS319
|
3.8
|
18.8
|
1.0
|
|
HB3
|
D:HIS319
|
4.0
|
18.4
|
1.0
|
|
NE2
|
D:HIS319
|
4.1
|
24.1
|
1.0
|
|
CA
|
D:CYS339
|
4.2
|
20.9
|
1.0
|
|
CD2
|
D:HIS319
|
4.2
|
26.3
|
1.0
|
|
HB2
|
D:CYS339
|
4.2
|
20.0
|
1.0
|
|
CB
|
D:ILE338
|
4.2
|
23.3
|
1.0
|
|
H
|
D:ILE338
|
4.3
|
24.6
|
1.0
|
|
HB2
|
D:GLN341
|
4.3
|
23.2
|
1.0
|
|
H
|
D:GLN341
|
4.4
|
24.2
|
1.0
|
|
N
|
D:HIS319
|
4.5
|
18.8
|
1.0
|
|
CA
|
D:CYS336
|
4.5
|
23.1
|
1.0
|
|
HD2
|
D:PHE314
|
4.6
|
15.2
|
1.0
|
|
CA
|
D:CYS317
|
4.6
|
16.4
|
1.0
|
|
CA
|
D:HIS319
|
4.6
|
18.4
|
1.0
|
|
HB2
|
D:PHE314
|
4.7
|
18.0
|
1.0
|
|
H
|
D:ARG340
|
4.7
|
22.5
|
1.0
|
|
C
|
D:ILE338
|
4.7
|
26.4
|
1.0
|
|
HG13
|
D:ILE338
|
4.8
|
28.2
|
1.0
|
|
HG22
|
D:ILE338
|
4.8
|
24.8
|
1.0
|
|
CA
|
D:ILE338
|
4.8
|
21.8
|
1.0
|
|
C
|
D:CYS339
|
4.9
|
22.6
|
1.0
|
|
N
|
D:ILE338
|
4.9
|
24.6
|
1.0
|
|
O
|
D:HOH510
|
4.9
|
23.5
|
1.0
|
|
HA
|
D:CYS336
|
4.9
|
23.1
|
1.0
|
|
HE2
|
D:HIS319
|
4.9
|
24.1
|
1.0
|
|
C
|
D:CYS317
|
4.9
|
15.7
|
1.0
|
|
HG21
|
D:ILE338
|
4.9
|
24.8
|
1.0
|
|
HG12
|
D:ILE338
|
4.9
|
28.2
|
1.0
|
|
CG2
|
D:ILE338
|
4.9
|
24.8
|
1.0
|
|
CG1
|
D:ILE338
|
5.0
|
28.2
|
1.0
|
|
HA
|
D:CYS339
|
5.0
|
20.9
|
1.0
|
|
C
|
D:CYS336
|
5.0
|
22.2
|
1.0
|
|
Zinc binding site 9 out
of 12 in 6m2d
Go back to
Zinc Binding Sites List in 6m2d
Zinc binding site 9 out
of 12 in the MUL1-Ring Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 9 of MUL1-Ring Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Zn401
b:29.1
occ:1.00
|
SG
|
E:CYS326
|
2.3
|
19.7
|
1.0
|
|
SG
|
E:CYS323
|
2.3
|
18.7
|
1.0
|
|
SG
|
E:CYS302
|
2.4
|
15.9
|
1.0
|
|
SG
|
E:CYS305
|
2.4
|
17.9
|
1.0
|
|
HB2
|
E:CYS326
|
2.8
|
19.3
|
1.0
|
|
HB3
|
E:CYS305
|
2.9
|
19.5
|
1.0
|
|
HB3
|
E:CYS302
|
3.0
|
20.5
|
1.0
|
|
H
|
E:CYS305
|
3.1
|
18.6
|
1.0
|
|
CB
|
E:CYS326
|
3.1
|
19.3
|
1.0
|
|
H
|
E:CYS323
|
3.1
|
18.1
|
1.0
|
|
CB
|
E:CYS302
|
3.2
|
20.5
|
1.0
|
|
CB
|
E:CYS305
|
3.2
|
19.5
|
1.0
|
|
HB2
|
E:CYS302
|
3.4
|
20.5
|
1.0
|
|
HB3
|
E:CYS323
|
3.4
|
16.7
|
1.0
|
|
CB
|
E:CYS323
|
3.5
|
16.7
|
1.0
|
|
H
|
E:CYS326
|
3.6
|
18.3
|
1.0
|
|
HB
|
E:VAL304
|
3.6
|
17.6
|
1.0
|
|
N
|
E:CYS305
|
3.7
|
18.6
|
1.0
|
|
HB3
|
E:CYS326
|
3.7
|
19.3
|
1.0
|
|
HB2
|
E:SER308
|
3.9
|
16.3
|
1.0
|
|
N
|
E:CYS323
|
3.9
|
18.1
|
1.0
|
|
HB2
|
E:CYS305
|
4.0
|
19.5
|
1.0
|
|
CA
|
E:CYS305
|
4.0
|
21.2
|
1.0
|
|
N
|
E:CYS326
|
4.2
|
18.3
|
1.0
|
|
CA
|
E:CYS326
|
4.2
|
19.9
|
1.0
|
|
O
|
E:HOH534
|
4.3
|
25.1
|
1.0
|
|
H
|
E:VAL304
|
4.3
|
17.8
|
1.0
|
|
CA
|
E:CYS323
|
4.3
|
16.8
|
1.0
|
|
HB2
|
E:CYS323
|
4.3
|
16.7
|
1.0
|
|
H
|
E:SER308
|
4.4
|
18.2
|
1.0
|
|
H
|
E:LEU306
|
4.5
|
20.8
|
1.0
|
|
CB
|
E:VAL304
|
4.6
|
17.6
|
1.0
|
|
HB3
|
E:GLU325
|
4.6
|
21.1
|
1.0
|
|
CA
|
E:CYS302
|
4.6
|
18.5
|
1.0
|
|
HA
|
E:SER322
|
4.6
|
15.1
|
1.0
|
|
HA
|
E:CYS326
|
4.6
|
19.9
|
1.0
|
|
C
|
E:VAL304
|
4.7
|
19.5
|
1.0
|
|
H
|
E:SER307
|
4.7
|
18.4
|
1.0
|
|
HA
|
E:CYS305
|
4.8
|
21.2
|
1.0
|
|
CB
|
E:SER308
|
4.8
|
16.3
|
1.0
|
|
C
|
E:CYS305
|
4.9
|
18.1
|
1.0
|
|
C
|
E:CYS323
|
4.9
|
18.6
|
1.0
|
|
N
|
E:VAL304
|
4.9
|
17.8
|
1.0
|
|
N
|
E:LEU306
|
4.9
|
20.8
|
1.0
|
|
CA
|
E:VAL304
|
5.0
|
17.9
|
1.0
|
|
O
|
E:CYS323
|
5.0
|
18.4
|
1.0
|
|
C
|
E:CYS302
|
5.0
|
22.7
|
1.0
|
|
Zinc binding site 10 out
of 12 in 6m2d
Go back to
Zinc Binding Sites List in 6m2d
Zinc binding site 10 out
of 12 in the MUL1-Ring Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 10 of MUL1-Ring Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Zn402
b:33.3
occ:1.00
|
ND1
|
E:HIS319
|
2.2
|
22.9
|
1.0
|
|
SG
|
E:CYS339
|
2.3
|
26.3
|
1.0
|
|
SG
|
E:CYS336
|
2.3
|
17.2
|
1.0
|
|
SG
|
E:CYS317
|
2.4
|
21.0
|
1.0
|
|
HB2
|
E:CYS317
|
2.8
|
28.6
|
1.0
|
|
HB2
|
E:HIS319
|
2.9
|
20.8
|
1.0
|
|
HB3
|
E:CYS336
|
2.9
|
20.7
|
1.0
|
|
CB
|
E:CYS336
|
3.0
|
20.7
|
1.0
|
|
H
|
E:CYS339
|
3.0
|
23.8
|
1.0
|
|
HB2
|
E:CYS336
|
3.1
|
20.7
|
1.0
|
|
CB
|
E:CYS317
|
3.1
|
28.6
|
1.0
|
|
HB3
|
E:CYS339
|
3.1
|
22.7
|
1.0
|
|
CE1
|
E:HIS319
|
3.1
|
26.0
|
1.0
|
|
CG
|
E:HIS319
|
3.2
|
22.6
|
1.0
|
|
HE1
|
E:HIS319
|
3.2
|
26.0
|
1.0
|
|
CB
|
E:CYS339
|
3.3
|
22.7
|
1.0
|
|
HB3
|
E:CYS317
|
3.4
|
28.6
|
1.0
|
|
CB
|
E:HIS319
|
3.5
|
20.8
|
1.0
|
|
HB
|
E:ILE338
|
3.7
|
21.1
|
1.0
|
|
N
|
E:CYS339
|
3.7
|
23.8
|
1.0
|
|
H
|
E:HIS319
|
3.8
|
23.2
|
1.0
|
|
HB2
|
E:CYS339
|
4.0
|
22.7
|
1.0
|
|
HB3
|
E:HIS319
|
4.0
|
20.8
|
1.0
|
|
CA
|
E:CYS339
|
4.0
|
25.4
|
1.0
|
|
HD2
|
E:PHE314
|
4.2
|
20.2
|
1.0
|
|
NE2
|
E:HIS319
|
4.2
|
26.2
|
1.0
|
|
CD2
|
E:HIS319
|
4.3
|
23.5
|
1.0
|
|
H
|
E:ILE338
|
4.4
|
21.3
|
1.0
|
|
HB2
|
E:GLN341
|
4.5
|
32.7
|
1.0
|
|
CA
|
E:CYS336
|
4.5
|
18.6
|
1.0
|
|
CA
|
E:CYS317
|
4.5
|
29.0
|
1.0
|
|
N
|
E:HIS319
|
4.5
|
23.2
|
1.0
|
|
CB
|
E:ILE338
|
4.6
|
21.1
|
1.0
|
|
HG22
|
E:ILE338
|
4.6
|
22.5
|
1.0
|
|
H
|
E:GLN341
|
4.6
|
28.9
|
1.0
|
|
CA
|
E:HIS319
|
4.6
|
23.8
|
1.0
|
|
O
|
E:HOH522
|
4.7
|
28.8
|
1.0
|
|
HB2
|
E:PHE314
|
4.7
|
22.5
|
1.0
|
|
H
|
E:ARG340
|
4.7
|
29.4
|
1.0
|
|
HE21
|
E:GLN341
|
4.8
|
40.0
|
1.0
|
|
C
|
E:ILE338
|
4.8
|
26.3
|
1.0
|
|
C
|
E:CYS339
|
4.8
|
28.9
|
1.0
|
|
C
|
E:CYS317
|
4.8
|
24.9
|
1.0
|
|
HA
|
E:CYS339
|
4.9
|
25.4
|
1.0
|
|
HA
|
E:CYS336
|
4.9
|
18.6
|
1.0
|
|
HG3
|
E:GLN341
|
4.9
|
38.9
|
1.0
|
|
N
|
E:ILE338
|
5.0
|
21.3
|
1.0
|
|
NE2
|
E:GLN341
|
5.0
|
40.0
|
1.0
|
|
CG2
|
E:ILE338
|
5.0
|
22.5
|
1.0
|
|
N
|
E:ARG340
|
5.0
|
29.4
|
1.0
|
|
Reference:
S.O.Lee,
K.S.Ryu,
S.-W.Chi.
Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain To Be Published.
Page generated: Tue Oct 29 02:52:37 2024
|
