Zinc in PDB 6m2c: Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain
Enzymatic activity of Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain
All present enzymatic activity of Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain:
2.3.2.23;
2.3.2.24;
2.3.2.27;
Protein crystallography data
The structure of Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain, PDB code: 6m2c
was solved by
S.O.Lee,
K.S.Ryu,
S.-W.Chi,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
45.64 /
2.70
|
|
Space group
|
P 1 21 1
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
47.207,
141.241,
68.047,
90,
104.81,
90
|
|
R / Rfree (%)
|
21.2 /
25.8
|
Zinc Binding Sites:
The binding sites of Zinc atom in the Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain
(pdb code 6m2c). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 8 binding sites of Zinc where determined in the
Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain, PDB code: 6m2c:
Jump to Zinc binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Zinc binding site 1 out
of 8 in 6m2c
Go back to
Zinc Binding Sites List in 6m2c
Zinc binding site 1 out
of 8 in the Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Zn401
b:27.6
occ:1.00
|
SG
|
E:CYS326
|
2.3
|
34.9
|
1.0
|
|
SG
|
E:CYS305
|
2.4
|
52.9
|
1.0
|
|
SG
|
E:CYS302
|
2.5
|
33.5
|
1.0
|
|
SG
|
E:CYS323
|
2.5
|
33.0
|
1.0
|
|
HB2
|
E:CYS326
|
2.8
|
28.2
|
1.0
|
|
HB3
|
E:CYS302
|
3.0
|
28.7
|
1.0
|
|
HB3
|
E:CYS305
|
3.1
|
31.2
|
1.0
|
|
H
|
E:CYS305
|
3.1
|
31.4
|
1.0
|
|
CB
|
E:CYS326
|
3.1
|
28.2
|
1.0
|
|
CB
|
E:CYS302
|
3.2
|
28.7
|
1.0
|
|
H
|
E:CYS323
|
3.2
|
31.0
|
1.0
|
|
CB
|
E:CYS305
|
3.3
|
31.2
|
1.0
|
|
HB2
|
E:CYS302
|
3.4
|
28.7
|
1.0
|
|
HB3
|
E:CYS323
|
3.4
|
36.3
|
1.0
|
|
HB
|
E:VAL304
|
3.5
|
27.6
|
1.0
|
|
CB
|
E:CYS323
|
3.6
|
36.3
|
1.0
|
|
HB3
|
E:CYS326
|
3.6
|
28.2
|
1.0
|
|
N
|
E:CYS305
|
3.7
|
31.4
|
1.0
|
|
H
|
E:CYS326
|
3.8
|
33.1
|
1.0
|
|
HB2
|
E:SER308
|
4.0
|
38.2
|
1.0
|
|
N
|
E:CYS323
|
4.0
|
31.0
|
1.0
|
|
CA
|
E:CYS305
|
4.1
|
28.2
|
1.0
|
|
HB2
|
E:CYS305
|
4.1
|
31.2
|
1.0
|
|
CA
|
E:CYS323
|
4.4
|
34.6
|
1.0
|
|
CA
|
E:CYS326
|
4.4
|
28.4
|
1.0
|
|
HB2
|
E:CYS323
|
4.4
|
36.3
|
1.0
|
|
H
|
E:VAL304
|
4.4
|
29.5
|
1.0
|
|
CB
|
E:VAL304
|
4.4
|
27.6
|
1.0
|
|
N
|
E:CYS326
|
4.4
|
33.1
|
1.0
|
|
H
|
E:LEU306
|
4.6
|
28.4
|
1.0
|
|
HG
|
E:SER308
|
4.6
|
44.1
|
1.0
|
|
H
|
E:SER308
|
4.6
|
32.0
|
1.0
|
|
C
|
E:VAL304
|
4.6
|
35.1
|
1.0
|
|
CA
|
E:CYS302
|
4.7
|
33.5
|
1.0
|
|
HA
|
E:SER322
|
4.7
|
29.7
|
1.0
|
|
HG
|
E:SER307
|
4.7
|
44.5
|
1.0
|
|
HA
|
E:CYS326
|
4.8
|
28.4
|
1.0
|
|
CB
|
E:SER308
|
4.8
|
38.2
|
1.0
|
|
OG
|
E:SER308
|
4.8
|
44.1
|
1.0
|
|
HE3
|
A:MET1
|
4.8
|
34.8
|
1.0
|
|
HA
|
E:CYS305
|
4.8
|
28.2
|
1.0
|
|
H
|
E:SER307
|
4.8
|
38.9
|
1.0
|
|
HG12
|
E:VAL304
|
4.9
|
18.4
|
1.0
|
|
C
|
E:CYS305
|
4.9
|
31.2
|
1.0
|
|
O
|
E:CYS323
|
4.9
|
36.3
|
1.0
|
|
CA
|
E:VAL304
|
4.9
|
33.5
|
1.0
|
|
OG
|
E:SER322
|
4.9
|
22.3
|
1.0
|
|
C
|
E:CYS323
|
4.9
|
40.7
|
1.0
|
|
HG
|
E:SER322
|
5.0
|
22.3
|
1.0
|
|
N
|
E:VAL304
|
5.0
|
29.5
|
1.0
|
|
N
|
E:LEU306
|
5.0
|
28.4
|
1.0
|
|
Zinc binding site 2 out
of 8 in 6m2c
Go back to
Zinc Binding Sites List in 6m2c
Zinc binding site 2 out
of 8 in the Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Zn402
b:33.3
occ:1.00
|
ND1
|
E:HIS319
|
2.0
|
33.7
|
1.0
|
|
SG
|
E:CYS317
|
2.3
|
32.5
|
1.0
|
|
SG
|
E:CYS339
|
2.3
|
38.2
|
1.0
|
|
SG
|
E:CYS336
|
2.4
|
32.0
|
1.0
|
|
HB2
|
E:CYS317
|
2.6
|
34.6
|
1.0
|
|
CE1
|
E:HIS319
|
2.6
|
37.7
|
1.0
|
|
HE1
|
E:HIS319
|
2.8
|
37.7
|
1.0
|
|
CB
|
E:CYS317
|
2.9
|
34.6
|
1.0
|
|
CG
|
E:HIS319
|
3.0
|
35.4
|
1.0
|
|
HB2
|
E:HIS319
|
3.2
|
31.9
|
1.0
|
|
HB3
|
E:CYS336
|
3.2
|
37.4
|
1.0
|
|
CB
|
E:CYS336
|
3.2
|
37.4
|
1.0
|
|
HB3
|
E:CYS317
|
3.2
|
34.6
|
1.0
|
|
HB2
|
E:CYS336
|
3.2
|
37.4
|
1.0
|
|
H
|
E:CYS339
|
3.4
|
31.8
|
1.0
|
|
HB
|
E:ILE338
|
3.5
|
37.1
|
1.0
|
|
CB
|
E:HIS319
|
3.6
|
31.9
|
1.0
|
|
CB
|
E:CYS339
|
3.7
|
34.5
|
1.0
|
|
HB3
|
E:CYS339
|
3.7
|
34.5
|
1.0
|
|
NE2
|
E:HIS319
|
3.7
|
41.0
|
1.0
|
|
CD2
|
E:HIS319
|
3.9
|
40.5
|
1.0
|
|
H
|
E:HIS319
|
3.9
|
32.9
|
1.0
|
|
N
|
E:CYS339
|
4.0
|
31.8
|
1.0
|
|
CA
|
E:CYS317
|
4.3
|
39.6
|
1.0
|
|
HB3
|
E:HIS319
|
4.3
|
31.9
|
1.0
|
|
H
|
E:ILE338
|
4.4
|
37.9
|
1.0
|
|
HB2
|
E:CYS339
|
4.4
|
34.5
|
1.0
|
|
HE2
|
E:HIS319
|
4.4
|
41.0
|
1.0
|
|
CA
|
E:CYS339
|
4.4
|
30.7
|
1.0
|
|
N
|
E:HIS319
|
4.4
|
32.9
|
1.0
|
|
CB
|
E:ILE338
|
4.5
|
37.1
|
1.0
|
|
C
|
E:CYS317
|
4.5
|
39.5
|
1.0
|
|
H
|
E:GLN341
|
4.6
|
45.0
|
1.0
|
|
HB2
|
E:GLN341
|
4.6
|
40.7
|
1.0
|
|
HB2
|
E:PHE314
|
4.7
|
27.7
|
1.0
|
|
CA
|
E:HIS319
|
4.7
|
30.9
|
1.0
|
|
CA
|
E:CYS336
|
4.7
|
38.7
|
1.0
|
|
HD2
|
E:HIS319
|
4.7
|
40.5
|
1.0
|
|
H
|
E:GLY318
|
4.8
|
31.6
|
1.0
|
|
HA
|
E:CYS317
|
4.8
|
39.6
|
1.0
|
|
N
|
E:GLY318
|
4.8
|
31.6
|
1.0
|
|
HD2
|
E:PHE314
|
4.8
|
30.5
|
1.0
|
|
HG3
|
E:GLN341
|
4.9
|
48.6
|
1.0
|
|
H
|
E:CYS317
|
4.9
|
39.6
|
1.0
|
|
C
|
E:ILE338
|
4.9
|
36.9
|
1.0
|
|
H
|
E:ARG340
|
5.0
|
32.7
|
1.0
|
|
O
|
E:CYS317
|
5.0
|
42.4
|
1.0
|
|
Zinc binding site 3 out
of 8 in 6m2c
Go back to
Zinc Binding Sites List in 6m2c
Zinc binding site 3 out
of 8 in the Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Zn401
b:38.2
occ:1.00
|
SG
|
F:CYS323
|
2.3
|
43.5
|
1.0
|
|
SG
|
F:CYS326
|
2.3
|
32.8
|
1.0
|
|
SG
|
F:CYS302
|
2.3
|
30.6
|
1.0
|
|
SG
|
F:CYS305
|
2.4
|
35.7
|
1.0
|
|
HB2
|
F:CYS326
|
2.9
|
28.3
|
1.0
|
|
HB3
|
F:CYS302
|
3.0
|
36.1
|
1.0
|
|
HB3
|
F:CYS305
|
3.0
|
34.6
|
1.0
|
|
H
|
F:CYS323
|
3.0
|
38.4
|
1.0
|
|
CB
|
F:CYS302
|
3.1
|
36.1
|
1.0
|
|
H
|
F:CYS305
|
3.1
|
33.1
|
1.0
|
|
CB
|
F:CYS326
|
3.2
|
28.3
|
1.0
|
|
HB3
|
F:CYS323
|
3.2
|
45.4
|
1.0
|
|
HB2
|
F:CYS302
|
3.2
|
36.1
|
1.0
|
|
CB
|
F:CYS305
|
3.3
|
34.6
|
1.0
|
|
CB
|
F:CYS323
|
3.3
|
45.4
|
1.0
|
|
HB
|
F:VAL304
|
3.6
|
33.0
|
1.0
|
|
HB2
|
F:SER308
|
3.7
|
48.2
|
1.0
|
|
HB3
|
F:CYS326
|
3.7
|
28.3
|
1.0
|
|
N
|
F:CYS305
|
3.7
|
33.1
|
1.0
|
|
H
|
F:CYS326
|
3.8
|
38.6
|
1.0
|
|
N
|
F:CYS323
|
3.8
|
38.4
|
1.0
|
|
HB2
|
F:CYS305
|
4.1
|
34.6
|
1.0
|
|
CA
|
F:CYS305
|
4.1
|
32.8
|
1.0
|
|
CA
|
F:CYS323
|
4.1
|
42.0
|
1.0
|
|
HB2
|
F:CYS323
|
4.1
|
45.4
|
1.0
|
|
CA
|
F:CYS326
|
4.4
|
36.3
|
1.0
|
|
H
|
F:VAL304
|
4.4
|
27.9
|
1.0
|
|
N
|
F:CYS326
|
4.4
|
38.6
|
1.0
|
|
HG
|
F:SER308
|
4.5
|
47.1
|
1.0
|
|
CB
|
F:SER308
|
4.5
|
48.2
|
1.0
|
|
CB
|
F:VAL304
|
4.6
|
33.0
|
1.0
|
|
CA
|
F:CYS302
|
4.6
|
40.3
|
1.0
|
|
H
|
F:SER308
|
4.6
|
42.3
|
1.0
|
|
H
|
F:LEU306
|
4.6
|
37.2
|
1.0
|
|
O
|
F:CYS323
|
4.6
|
44.6
|
1.0
|
|
OG
|
F:SER308
|
4.7
|
47.1
|
1.0
|
|
C
|
F:CYS323
|
4.7
|
45.3
|
1.0
|
|
C
|
F:VAL304
|
4.7
|
34.6
|
1.0
|
|
HA
|
F:SER322
|
4.7
|
36.6
|
1.0
|
|
HA
|
F:CYS326
|
4.8
|
36.3
|
1.0
|
|
OG
|
F:SER322
|
4.8
|
39.8
|
1.0
|
|
HA
|
F:CYS305
|
4.9
|
32.8
|
1.0
|
|
HE1
|
B:MET1
|
4.9
|
30.1
|
1.0
|
|
HA
|
F:CYS323
|
4.9
|
42.0
|
1.0
|
|
HG
|
F:SER322
|
5.0
|
39.8
|
1.0
|
|
C
|
F:CYS305
|
5.0
|
35.9
|
1.0
|
|
C
|
F:SER322
|
5.0
|
42.8
|
1.0
|
|
H
|
F:SER307
|
5.0
|
47.4
|
1.0
|
|
HA
|
F:CYS302
|
5.0
|
40.3
|
1.0
|
|
Zinc binding site 4 out
of 8 in 6m2c
Go back to
Zinc Binding Sites List in 6m2c
Zinc binding site 4 out
of 8 in the Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Zn402
b:35.0
occ:1.00
|
SG
|
F:CYS339
|
2.3
|
63.7
|
1.0
|
|
ND1
|
F:HIS319
|
2.4
|
38.6
|
1.0
|
|
SG
|
F:CYS336
|
2.5
|
25.1
|
1.0
|
|
SG
|
F:CYS317
|
2.5
|
33.9
|
1.0
|
|
HB2
|
F:CYS317
|
2.9
|
36.3
|
1.0
|
|
HB2
|
F:HIS319
|
3.0
|
38.8
|
1.0
|
|
HB3
|
F:CYS336
|
3.1
|
33.3
|
1.0
|
|
CB
|
F:CYS336
|
3.2
|
33.3
|
1.0
|
|
CB
|
F:CYS317
|
3.2
|
36.3
|
1.0
|
|
HB2
|
F:CYS336
|
3.2
|
33.3
|
1.0
|
|
CE1
|
F:HIS319
|
3.3
|
45.3
|
1.0
|
|
CG
|
F:HIS319
|
3.3
|
43.2
|
1.0
|
|
H
|
F:CYS339
|
3.4
|
36.3
|
1.0
|
|
HB3
|
F:CYS339
|
3.5
|
36.9
|
1.0
|
|
HE1
|
F:HIS319
|
3.5
|
45.3
|
1.0
|
|
HB3
|
F:CYS317
|
3.5
|
36.3
|
1.0
|
|
CB
|
F:CYS339
|
3.6
|
36.9
|
1.0
|
|
HB
|
F:ILE338
|
3.6
|
27.4
|
1.0
|
|
CB
|
F:HIS319
|
3.6
|
38.8
|
1.0
|
|
N
|
F:CYS339
|
3.9
|
36.3
|
1.0
|
|
H
|
F:HIS319
|
4.0
|
31.6
|
1.0
|
|
HB3
|
F:HIS319
|
4.2
|
38.8
|
1.0
|
|
HD2
|
F:PHE314
|
4.2
|
32.6
|
1.0
|
|
HB2
|
F:CYS339
|
4.3
|
36.9
|
1.0
|
|
CA
|
F:CYS339
|
4.4
|
40.0
|
1.0
|
|
H
|
F:ILE338
|
4.4
|
35.2
|
1.0
|
|
NE2
|
F:HIS319
|
4.4
|
47.1
|
1.0
|
|
CD2
|
F:HIS319
|
4.4
|
50.5
|
1.0
|
|
CB
|
F:ILE338
|
4.5
|
27.4
|
1.0
|
|
HB2
|
F:PHE314
|
4.5
|
34.1
|
1.0
|
|
HB2
|
F:GLN341
|
4.5
|
51.6
|
1.0
|
|
N
|
F:HIS319
|
4.6
|
31.6
|
1.0
|
|
CA
|
F:CYS317
|
4.6
|
36.0
|
1.0
|
|
HG22
|
F:ILE338
|
4.6
|
22.4
|
1.0
|
|
CA
|
F:CYS336
|
4.7
|
36.8
|
1.0
|
|
CA
|
F:HIS319
|
4.7
|
34.6
|
1.0
|
|
C
|
F:ILE338
|
4.8
|
39.7
|
1.0
|
|
C
|
F:CYS317
|
4.9
|
39.3
|
1.0
|
|
H
|
F:GLN341
|
4.9
|
43.5
|
1.0
|
|
CG2
|
F:ILE338
|
5.0
|
22.4
|
1.0
|
|
HG21
|
F:ILE338
|
5.0
|
22.4
|
1.0
|
|
Zinc binding site 5 out
of 8 in 6m2c
Go back to
Zinc Binding Sites List in 6m2c
Zinc binding site 5 out
of 8 in the Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Zn401
b:29.6
occ:1.00
|
SG
|
G:CYS326
|
2.2
|
30.2
|
1.0
|
|
SG
|
G:CYS302
|
2.2
|
29.6
|
1.0
|
|
SG
|
G:CYS323
|
2.3
|
30.9
|
1.0
|
|
SG
|
G:CYS305
|
2.4
|
36.8
|
1.0
|
|
HB2
|
G:CYS326
|
2.8
|
31.9
|
1.0
|
|
HB3
|
G:CYS302
|
2.9
|
31.2
|
1.0
|
|
CB
|
G:CYS302
|
3.0
|
31.2
|
1.0
|
|
H
|
G:CYS305
|
3.1
|
38.6
|
1.0
|
|
CB
|
G:CYS326
|
3.1
|
31.9
|
1.0
|
|
H
|
G:CYS323
|
3.1
|
31.5
|
1.0
|
|
HB3
|
G:CYS305
|
3.2
|
38.8
|
1.0
|
|
HB2
|
G:CYS302
|
3.2
|
31.2
|
1.0
|
|
HB3
|
G:CYS323
|
3.3
|
32.9
|
1.0
|
|
CB
|
G:CYS305
|
3.4
|
38.8
|
1.0
|
|
CB
|
G:CYS323
|
3.4
|
32.9
|
1.0
|
|
HB3
|
G:CYS326
|
3.6
|
31.9
|
1.0
|
|
H
|
G:CYS326
|
3.7
|
27.9
|
1.0
|
|
N
|
G:CYS305
|
3.7
|
38.6
|
1.0
|
|
HB
|
G:VAL304
|
3.8
|
32.4
|
1.0
|
|
HB2
|
G:SER308
|
3.8
|
41.1
|
1.0
|
|
N
|
G:CYS323
|
3.9
|
31.5
|
1.0
|
|
CA
|
G:CYS305
|
4.1
|
37.5
|
1.0
|
|
HB2
|
G:CYS305
|
4.2
|
38.8
|
1.0
|
|
CA
|
G:CYS323
|
4.2
|
32.5
|
1.0
|
|
HB2
|
G:CYS323
|
4.2
|
32.9
|
1.0
|
|
H
|
G:VAL304
|
4.3
|
36.0
|
1.0
|
|
CA
|
G:CYS326
|
4.3
|
27.5
|
1.0
|
|
N
|
G:CYS326
|
4.3
|
27.9
|
1.0
|
|
H
|
G:SER308
|
4.4
|
37.3
|
1.0
|
|
H
|
G:LEU306
|
4.5
|
39.9
|
1.0
|
|
CA
|
G:CYS302
|
4.5
|
32.4
|
1.0
|
|
O
|
G:CYS323
|
4.7
|
32.5
|
1.0
|
|
CB
|
G:SER308
|
4.7
|
41.1
|
1.0
|
|
HA
|
G:CYS326
|
4.7
|
27.5
|
1.0
|
|
CB
|
G:VAL304
|
4.7
|
32.4
|
1.0
|
|
H
|
G:SER307
|
4.7
|
40.9
|
1.0
|
|
HA
|
G:SER322
|
4.7
|
31.5
|
1.0
|
|
C
|
G:CYS323
|
4.7
|
34.2
|
1.0
|
|
C
|
G:VAL304
|
4.8
|
36.7
|
1.0
|
|
HB2
|
G:GLU325
|
4.8
|
34.8
|
1.0
|
|
C
|
G:CYS302
|
4.8
|
33.4
|
1.0
|
|
OG
|
G:SER322
|
4.8
|
34.5
|
1.0
|
|
HG
|
G:SER308
|
4.9
|
33.9
|
1.0
|
|
OG
|
G:SER308
|
4.9
|
33.9
|
1.0
|
|
C
|
G:CYS305
|
4.9
|
38.6
|
1.0
|
|
N
|
G:LEU306
|
4.9
|
39.9
|
1.0
|
|
N
|
G:VAL304
|
4.9
|
36.0
|
1.0
|
|
O
|
G:CYS302
|
4.9
|
34.8
|
1.0
|
|
O
|
G:HOH502
|
4.9
|
31.5
|
1.0
|
|
HA
|
G:CYS305
|
4.9
|
37.5
|
1.0
|
|
HA
|
G:CYS302
|
4.9
|
32.4
|
1.0
|
|
HG
|
G:SER322
|
5.0
|
34.5
|
1.0
|
|
Zinc binding site 6 out
of 8 in 6m2c
Go back to
Zinc Binding Sites List in 6m2c
Zinc binding site 6 out
of 8 in the Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Zn402
b:43.6
occ:1.00
|
ND1
|
G:HIS319
|
2.1
|
38.1
|
1.0
|
|
SG
|
G:CYS339
|
2.2
|
57.8
|
1.0
|
|
SG
|
G:CYS317
|
2.4
|
50.2
|
1.0
|
|
HB2
|
G:CYS317
|
2.5
|
44.0
|
1.0
|
|
SG
|
G:CYS336
|
2.5
|
29.8
|
1.0
|
|
CB
|
G:CYS317
|
2.8
|
44.0
|
1.0
|
|
HB2
|
G:HIS319
|
2.9
|
39.2
|
1.0
|
|
CE1
|
G:HIS319
|
3.0
|
33.6
|
1.0
|
|
CG
|
G:HIS319
|
3.1
|
42.5
|
1.0
|
|
HB3
|
G:CYS336
|
3.1
|
34.6
|
1.0
|
|
HE1
|
G:HIS319
|
3.1
|
33.6
|
1.0
|
|
HB3
|
G:CYS317
|
3.1
|
44.0
|
1.0
|
|
HB2
|
G:CYS336
|
3.1
|
34.6
|
1.0
|
|
CB
|
G:CYS336
|
3.2
|
34.6
|
1.0
|
|
HB3
|
G:CYS339
|
3.4
|
50.0
|
1.0
|
|
CB
|
G:HIS319
|
3.4
|
39.2
|
1.0
|
|
CB
|
G:CYS339
|
3.5
|
50.0
|
1.0
|
|
H
|
G:CYS339
|
3.6
|
37.7
|
1.0
|
|
HB
|
G:ILE338
|
3.8
|
38.5
|
1.0
|
|
H
|
G:HIS319
|
3.9
|
43.8
|
1.0
|
|
HB3
|
G:HIS319
|
4.0
|
39.2
|
1.0
|
|
N
|
G:CYS339
|
4.1
|
37.7
|
1.0
|
|
NE2
|
G:HIS319
|
4.1
|
43.7
|
1.0
|
|
CD2
|
G:HIS319
|
4.2
|
45.3
|
1.0
|
|
HB2
|
G:CYS339
|
4.2
|
50.0
|
1.0
|
|
CA
|
G:CYS317
|
4.3
|
41.8
|
1.0
|
|
HG3
|
G:GLN341
|
4.3
|
51.9
|
1.0
|
|
CA
|
G:CYS339
|
4.4
|
36.7
|
1.0
|
|
HG2
|
G:GLN341
|
4.4
|
51.9
|
1.0
|
|
N
|
G:HIS319
|
4.5
|
43.8
|
1.0
|
|
C
|
G:CYS317
|
4.6
|
39.3
|
1.0
|
|
H
|
G:ILE338
|
4.6
|
38.1
|
1.0
|
|
HB2
|
G:PHE314
|
4.6
|
34.1
|
1.0
|
|
CA
|
G:HIS319
|
4.6
|
44.4
|
1.0
|
|
CA
|
G:CYS336
|
4.7
|
36.6
|
1.0
|
|
H
|
G:GLN341
|
4.7
|
48.6
|
1.0
|
|
HA
|
G:CYS317
|
4.8
|
41.8
|
1.0
|
|
CB
|
G:ILE338
|
4.8
|
38.5
|
1.0
|
|
HD2
|
G:PHE314
|
4.8
|
38.4
|
1.0
|
|
CG
|
G:GLN341
|
4.8
|
51.9
|
1.0
|
|
H
|
G:GLY318
|
4.9
|
39.3
|
1.0
|
|
HE2
|
G:HIS319
|
4.9
|
43.7
|
1.0
|
|
N
|
G:GLY318
|
4.9
|
39.3
|
1.0
|
|
H
|
G:CYS317
|
5.0
|
47.3
|
1.0
|
|
HG22
|
G:ILE338
|
5.0
|
42.8
|
1.0
|
|
O
|
G:CYS317
|
5.0
|
42.0
|
1.0
|
|
C
|
G:ILE338
|
5.0
|
44.5
|
1.0
|
|
Zinc binding site 7 out
of 8 in 6m2c
Go back to
Zinc Binding Sites List in 6m2c
Zinc binding site 7 out
of 8 in the Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 7 of Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
H:Zn401
b:33.5
occ:1.00
|
SG
|
H:CYS326
|
2.3
|
41.3
|
1.0
|
|
SG
|
H:CYS302
|
2.3
|
31.1
|
1.0
|
|
SG
|
H:CYS323
|
2.4
|
29.4
|
1.0
|
|
SG
|
H:CYS305
|
2.5
|
52.1
|
1.0
|
|
HB3
|
H:CYS302
|
2.8
|
36.1
|
1.0
|
|
HB2
|
H:CYS326
|
2.9
|
31.9
|
1.0
|
|
HB3
|
H:CYS305
|
3.0
|
35.8
|
1.0
|
|
H
|
H:CYS305
|
3.0
|
36.5
|
1.0
|
|
CB
|
H:CYS302
|
3.0
|
36.1
|
1.0
|
|
HB2
|
H:CYS302
|
3.2
|
36.1
|
1.0
|
|
CB
|
H:CYS326
|
3.2
|
31.9
|
1.0
|
|
CB
|
H:CYS305
|
3.2
|
35.8
|
1.0
|
|
H
|
H:CYS323
|
3.3
|
32.8
|
1.0
|
|
HB3
|
H:CYS323
|
3.4
|
30.4
|
1.0
|
|
HB
|
H:VAL304
|
3.5
|
24.3
|
1.0
|
|
CB
|
H:CYS323
|
3.6
|
30.4
|
1.0
|
|
HB2
|
H:SER308
|
3.6
|
36.9
|
1.0
|
|
N
|
H:CYS305
|
3.6
|
36.5
|
1.0
|
|
HB3
|
H:CYS326
|
3.7
|
31.9
|
1.0
|
|
H
|
H:CYS326
|
3.9
|
35.0
|
1.0
|
|
N
|
H:CYS323
|
4.0
|
32.8
|
1.0
|
|
CA
|
H:CYS305
|
4.0
|
38.4
|
1.0
|
|
HB2
|
H:CYS305
|
4.0
|
35.8
|
1.0
|
|
HG
|
H:SER308
|
4.1
|
47.8
|
1.0
|
|
H
|
H:VAL304
|
4.2
|
37.1
|
1.0
|
|
HB2
|
H:CYS323
|
4.3
|
30.4
|
1.0
|
|
CA
|
H:CYS323
|
4.3
|
34.1
|
1.0
|
|
CA
|
H:CYS326
|
4.4
|
35.0
|
1.0
|
|
CB
|
H:VAL304
|
4.4
|
24.3
|
1.0
|
|
CA
|
H:CYS302
|
4.5
|
35.9
|
1.0
|
|
CB
|
H:SER308
|
4.5
|
36.9
|
1.0
|
|
H
|
H:LEU306
|
4.5
|
44.2
|
1.0
|
|
N
|
H:CYS326
|
4.5
|
35.0
|
1.0
|
|
H
|
H:SER308
|
4.5
|
42.4
|
1.0
|
|
C
|
H:VAL304
|
4.6
|
33.3
|
1.0
|
|
OG
|
H:SER308
|
4.6
|
47.8
|
1.0
|
|
HA
|
H:SER322
|
4.7
|
28.0
|
1.0
|
|
HA
|
H:CYS305
|
4.8
|
38.4
|
1.0
|
|
HA
|
H:CYS326
|
4.8
|
35.0
|
1.0
|
|
N
|
H:VAL304
|
4.8
|
37.1
|
1.0
|
|
CA
|
H:VAL304
|
4.8
|
34.9
|
1.0
|
|
C
|
H:CYS302
|
4.8
|
36.2
|
1.0
|
|
O
|
H:CYS323
|
4.8
|
36.8
|
1.0
|
|
C
|
H:CYS305
|
4.9
|
43.5
|
1.0
|
|
C
|
H:CYS323
|
4.9
|
35.0
|
1.0
|
|
HA
|
H:CYS302
|
4.9
|
35.9
|
1.0
|
|
H
|
H:SER307
|
4.9
|
40.2
|
1.0
|
|
HG12
|
H:VAL304
|
4.9
|
24.6
|
1.0
|
|
N
|
H:LEU306
|
4.9
|
44.2
|
1.0
|
|
OG
|
H:SER322
|
5.0
|
28.3
|
1.0
|
|
Zinc binding site 8 out
of 8 in 6m2c
Go back to
Zinc Binding Sites List in 6m2c
Zinc binding site 8 out
of 8 in the Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 8 of Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
H:Zn402
b:26.5
occ:1.00
|
ND1
|
H:HIS319
|
2.2
|
23.3
|
1.0
|
|
SG
|
H:CYS336
|
2.3
|
28.3
|
1.0
|
|
SG
|
H:CYS339
|
2.4
|
38.2
|
1.0
|
|
SG
|
H:CYS317
|
2.5
|
28.1
|
1.0
|
|
HB2
|
H:HIS319
|
2.8
|
22.6
|
1.0
|
|
HB2
|
H:CYS317
|
2.9
|
30.2
|
1.0
|
|
HB3
|
H:CYS336
|
2.9
|
21.2
|
1.0
|
|
HB2
|
H:CYS336
|
2.9
|
21.2
|
1.0
|
|
CB
|
H:CYS336
|
2.9
|
21.2
|
1.0
|
|
CG
|
H:HIS319
|
3.1
|
25.9
|
1.0
|
|
CE1
|
H:HIS319
|
3.1
|
25.8
|
1.0
|
|
CB
|
H:CYS317
|
3.2
|
30.2
|
1.0
|
|
HE1
|
H:HIS319
|
3.3
|
25.8
|
1.0
|
|
CB
|
H:HIS319
|
3.4
|
22.6
|
1.0
|
|
HB3
|
H:CYS317
|
3.5
|
30.2
|
1.0
|
|
H
|
H:CYS339
|
3.6
|
26.5
|
1.0
|
|
HB3
|
H:HIS319
|
3.8
|
22.6
|
1.0
|
|
CB
|
H:CYS339
|
3.9
|
35.7
|
1.0
|
|
HB
|
H:ILE338
|
4.0
|
34.8
|
1.0
|
|
HB3
|
H:CYS339
|
4.0
|
35.7
|
1.0
|
|
H
|
H:HIS319
|
4.1
|
26.4
|
1.0
|
|
NE2
|
H:HIS319
|
4.2
|
24.4
|
1.0
|
|
CD2
|
H:HIS319
|
4.3
|
25.0
|
1.0
|
|
N
|
H:CYS339
|
4.3
|
26.5
|
1.0
|
|
HD2
|
H:PHE314
|
4.3
|
31.8
|
1.0
|
|
HB2
|
H:GLN341
|
4.3
|
39.0
|
1.0
|
|
H
|
H:GLN341
|
4.4
|
30.3
|
1.0
|
|
CA
|
H:CYS336
|
4.4
|
27.3
|
1.0
|
|
H
|
H:ILE338
|
4.5
|
34.4
|
1.0
|
|
HB2
|
H:PHE314
|
4.5
|
34.2
|
1.0
|
|
CA
|
H:CYS317
|
4.6
|
34.0
|
1.0
|
|
HB2
|
H:CYS339
|
4.6
|
35.7
|
1.0
|
|
N
|
H:HIS319
|
4.6
|
26.4
|
1.0
|
|
CA
|
H:HIS319
|
4.6
|
25.8
|
1.0
|
|
CA
|
H:CYS339
|
4.6
|
32.2
|
1.0
|
|
HA
|
H:CYS336
|
4.8
|
27.3
|
1.0
|
|
CB
|
H:ILE338
|
4.9
|
34.8
|
1.0
|
|
C
|
H:CYS317
|
4.9
|
31.7
|
1.0
|
|
Reference:
S.O.Lee,
K.S.Ryu,
S.-W.Chi.
Distinct Mechanism of MUL1-Ring Domain Simultaneously Recruiting E2 Enzyme and the Substrate P53-Tad Domain To Be Published.
Page generated: Tue Oct 29 02:52:37 2024
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