Zinc in PDB 6lhd: Crystal Structure of P53/Bcl-Xl Fusion Complex

The structure of Crystal Structure of P53/Bcl-Xl Fusion Complex, PDB code: 6lhd was solved by H.Wei, Y.Chen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.22 / 2.50
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	72.221, 68.85, 75.028, 90, 110.27, 90
R / Rfree (%)	20.2 / 26

The binding sites of Zinc atom in the Crystal Structure of P53/Bcl-Xl Fusion Complex (pdb code 6lhd). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of P53/Bcl-Xl Fusion Complex, PDB code: 6lhd:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of P53/Bcl-Xl Fusion Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of P53/Bcl-Xl Fusion Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:41.6 occ:1.00 ND1 A:HIS245 2.1 50.0 1.0 SG A:CYS304 2.4 48.4 1.0 SG A:CYS242 2.4 38.6 1.0 SG A:CYS308 2.4 48.2 1.0 CE1 A:HIS245 3.0 49.0 1.0 CG A:HIS245 3.1 44.7 1.0 CB A:CYS308 3.2 41.1 1.0 CB A:CYS242 3.5 36.0 1.0 CB A:HIS245 3.6 39.1 1.0 CB A:CYS304 3.7 40.0 1.0 CA A:CYS304 4.0 35.6 1.0 N A:CYS242 4.1 45.8 1.0 N A:ASN305 4.1 28.9 1.0 NE2 A:HIS245 4.1 51.6 1.0 CD2 A:HIS245 4.2 47.4 1.0 CA A:CYS242 4.4 40.6 1.0 N A:HIS245 4.4 38.6 1.0 C A:CYS304 4.6 39.1 1.0 CA A:CYS308 4.6 38.7 1.0 CA A:HIS245 4.6 36.4 1.0 O A:ASN305 4.9 47.0 1.0 O A:CYS242 4.9 44.2 1.0 C A:CYS242 4.9 39.7 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of P53/Bcl-Xl Fusion Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of P53/Bcl-Xl Fusion Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn401 b:39.6 occ:1.00 ND1 B:HIS245 2.0 39.4 1.0 SG B:CYS308 2.3 45.0 1.0 SG B:CYS242 2.4 42.6 1.0 SG B:CYS304 2.6 54.9 1.0 CE1 B:HIS245 2.9 39.3 1.0 CB B:CYS308 3.1 46.7 1.0 CG B:HIS245 3.1 40.5 1.0 CB B:CYS242 3.4 44.0 1.0 CB B:HIS245 3.6 40.4 1.0 CB B:CYS304 3.8 52.0 1.0 CA B:CYS304 4.0 46.6 1.0 N B:CYS242 4.0 42.5 1.0 NE2 B:HIS245 4.1 42.3 1.0 CD2 B:HIS245 4.2 38.7 1.0 N B:ASN305 4.3 47.2 1.0 CA B:CYS242 4.3 44.0 1.0 N B:HIS245 4.4 42.7 1.0 CA B:CYS308 4.5 49.7 1.0 C B:CYS304 4.6 49.0 1.0 CA B:HIS245 4.7 44.9 1.0 O B:MET303 4.8 37.2 1.0 O B:ASN305 4.9 44.1 1.0 O B:CYS242 5.0 45.1 1.0 C B:CYS242 5.0 44.7 1.0

H.Wei, Y.Zhang, L.Qu, Y.Feng, S.Dai, Y.Li, X.Chen, L.Jiang, M.Guo, J.Li, Z.Chen, L.Chen, Y.Chen. Structure of the Human P53/Bcl-Xl Complex To Be Published.