Zinc in PDB 6ldi: The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex

All present enzymatic activity of The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex:
2.7.7.6;

The structure of The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex also contains other interesting chemical elements:

Silver	(Ag)	1 atom
Magnesium	(Mg)	1 atom

The binding sites of Zinc atom in the The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex (pdb code 6ldi). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex, PDB code: 6ldi:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1501 b:0.9 occ:1.00 SG D:CYS70 2.5 64.9 1.0 SG D:CYS88 2.5 67.7 1.0 SG D:CYS85 2.5 71.8 1.0 CB D:CYS85 2.6 71.8 1.0 CB D:CYS70 2.6 64.9 1.0 SG D:CYS72 2.8 65.5 1.0 CA D:CYS70 4.0 64.9 1.0 CB D:CYS88 4.1 67.7 1.0 CA D:CYS85 4.1 71.8 1.0 N D:LEU71 4.1 60.5 1.0 N D:CYS72 4.2 65.5 1.0 CB D:CYS72 4.4 65.5 1.0 N D:CYS88 4.4 67.7 1.0 C D:CYS70 4.5 64.9 1.0 CB D:LYS74 4.5 73.8 1.0 CD1 D:TYR75 4.6 74.1 1.0 N D:LYS74 4.6 73.8 1.0 N D:GLY73 4.8 69.0 1.0 CA D:CYS88 4.8 67.7 1.0 CA D:CYS72 4.8 65.5 1.0 N D:CYS85 4.9 71.8 1.0 C D:CYS85 4.9 71.8 1.0 N D:CYS70 5.0 64.9 1.0

Zinc binding site 2 out of 2 in the The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1502 b:0.4 occ:1.00 SG D:CYS898 2.5 45.2 1.0 SG D:CYS888 2.5 46.8 1.0 SG D:CYS895 2.5 50.9 1.0 SG D:CYS814 2.5 57.5 1.0 CB D:CYS895 3.0 50.9 1.0 CB D:CYS898 3.4 45.2 1.0 CB D:CYS814 3.7 57.5 1.0 CB D:CYS888 3.9 46.8 1.0 N D:CYS814 3.9 57.5 1.0 O D:CYS814 4.1 57.5 1.0 CA D:CYS895 4.1 50.9 1.0 N D:CYS895 4.1 50.9 1.0 CA D:CYS888 4.2 46.8 1.0 N D:ASP889 4.2 56.4 1.0 CA D:CYS814 4.3 57.5 1.0 CA D:CYS898 4.6 45.2 1.0 C D:CYS814 4.6 57.5 1.0 N D:CYS898 4.6 45.2 1.0 CG2 D:THR890 4.6 53.0 1.0 C D:CYS888 4.8 46.8 1.0 CG2 D:THR816 4.8 63.1 1.0 NH1 D:ARG883 4.9 47.3 1.0 C D:ASP813 4.9 55.8 1.0

C.Fang, S.J.Philips, X.Wu, K.Chen, J.Shi, L.Shen, J.Xu, Y.Feng, T.V.O'halloran, Y.Zhang. Cuer Activates Transcription Through A Dna Distortion Mechanism. Nat.Chem.Biol. 2020.
ISSN: ESSN 1552-4469
PubMed: 32989300
DOI: 10.1038/S41589-020-00653-X