Atomistry » Zinc » PDB 6ku2-6l6q » 6l0b
Atomistry »
  Zinc »
    PDB 6ku2-6l6q »
      6l0b »

Zinc in PDB 6l0b: Crystal Structure of Dihydroorotase in Complex with Fluorouracil From Saccharomyces Cerevisiae

Enzymatic activity of Crystal Structure of Dihydroorotase in Complex with Fluorouracil From Saccharomyces Cerevisiae

All present enzymatic activity of Crystal Structure of Dihydroorotase in Complex with Fluorouracil From Saccharomyces Cerevisiae:
3.5.2.3;

Protein crystallography data

The structure of Crystal Structure of Dihydroorotase in Complex with Fluorouracil From Saccharomyces Cerevisiae, PDB code: 6l0b was solved by H.H.Guan, Y.H.Huang, C.Y.Huang, C.J.Chen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 29.94 / 2.70
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 85.474, 88.430, 103.165, 90.00, 95.41, 90.00
R / Rfree (%) 19 / 24.9

Other elements in 6l0b:

The structure of Crystal Structure of Dihydroorotase in Complex with Fluorouracil From Saccharomyces Cerevisiae also contains other interesting chemical elements:

Fluorine (F) 4 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Dihydroorotase in Complex with Fluorouracil From Saccharomyces Cerevisiae (pdb code 6l0b). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 8 binding sites of Zinc where determined in the Crystal Structure of Dihydroorotase in Complex with Fluorouracil From Saccharomyces Cerevisiae, PDB code: 6l0b:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Zinc binding site 1 out of 8 in 6l0b

Go back to Zinc Binding Sites List in 6l0b
Zinc binding site 1 out of 8 in the Crystal Structure of Dihydroorotase in Complex with Fluorouracil From Saccharomyces Cerevisiae


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Dihydroorotase in Complex with Fluorouracil From Saccharomyces Cerevisiae within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn401

b:43.0
occ:1.00
 NE2 A:HIS16 2.1 34.2 1.0
NE2 A:HIS14 2.2 30.6 1.0
OQ1 A:KCX98 2.3 40.8 1.0
OD1 A:ASP258 2.3 36.3 1.0
CE1 A:HIS16 2.9 32.9 1.0
CG A:ASP258 3.0 35.5 1.0
CX A:KCX98 3.0 37.7 1.0
OQ2 A:KCX98 3.0 37.3 1.0
O2 A:URF403 3.0 36.8 1.0
CD2 A:HIS14 3.0 32.9 1.0
CD2 A:HIS16 3.2 34.0 1.0
N3 A:URF403 3.2 40.4 1.0
CE1 A:HIS14 3.3 30.3 1.0
C2 A:URF403 3.4 43.9 1.0
OD2 A:ASP258 3.4 36.6 1.0
ZN A:ZN402 3.5 42.8 1.0
CB A:ASP258 4.0 35.1 1.0
ND1 A:HIS16 4.0 32.7 1.0
CG A:HIS16 4.2 34.3 1.0
NZ A:KCX98 4.2 34.1 1.0
CG A:HIS14 4.3 34.7 1.0
ND1 A:HIS14 4.3 32.0 1.0
C4 A:URF403 4.4 38.8 1.0
CD2 A:HIS180 4.5 33.5 1.0
CA A:ASP258 4.5 35.1 1.0
NE2 A:HIS180 4.6 37.5 1.0
N1 A:URF403 4.6 45.4 1.0
OH A:TYR100 4.7 33.5 1.0
CG A:MET41 4.8 40.2 1.0
O4 A:URF403 4.9 37.2 1.0

Zinc binding site 2 out of 8 in 6l0b

Go back to Zinc Binding Sites List in 6l0b
Zinc binding site 2 out of 8 in the Crystal Structure of Dihydroorotase in Complex with Fluorouracil From Saccharomyces Cerevisiae


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Dihydroorotase in Complex with Fluorouracil From Saccharomyces Cerevisiae within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn402

b:42.8
occ:1.00
 ND1 A:HIS137 2.1 39.6 1.0
OQ2 A:KCX98 2.1 37.3 1.0
NE2 A:HIS180 2.4 37.5 1.0
O2 A:URF403 2.4 36.8 1.0
CE1 A:HIS137 2.8 37.6 1.0
CX A:KCX98 3.1 37.7 1.0
CG A:HIS137 3.3 38.9 1.0
CD2 A:HIS180 3.3 33.5 1.0
CE1 A:HIS180 3.4 38.2 1.0
ZN A:ZN401 3.5 43.0 1.0
C2 A:URF403 3.5 43.9 1.0
OQ1 A:KCX98 3.6 40.8 1.0
CB A:HIS137 3.8 37.3 1.0
NE2 A:HIS137 4.0 37.9 1.0
NZ A:KCX98 4.2 34.1 1.0
CD2 A:HIS137 4.2 38.1 1.0
O A:LYS230 4.2 36.0 1.0
NE2 A:HIS14 4.2 30.6 1.0
CE1 A:HIS14 4.3 30.3 1.0
OD2 A:ASP258 4.3 36.6 1.0
N3 A:URF403 4.4 40.4 1.0
ND1 A:HIS180 4.5 38.4 1.0
CG A:HIS180 4.5 38.2 1.0
CE1 A:TYR100 4.5 37.2 1.0
CE A:KCX98 4.6 32.4 1.0
N1 A:URF403 4.6 45.4 1.0
CG2 A:THR105 4.7 35.8 1.0
CA A:HIS137 4.8 40.5 1.0
OG1 A:THR105 4.8 41.0 1.0
CD1 A:TYR100 4.9 37.2 1.0
CG A:ASP258 4.9 35.5 1.0

Zinc binding site 3 out of 8 in 6l0b

Go back to Zinc Binding Sites List in 6l0b
Zinc binding site 3 out of 8 in the Crystal Structure of Dihydroorotase in Complex with Fluorouracil From Saccharomyces Cerevisiae


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of Dihydroorotase in Complex with Fluorouracil From Saccharomyces Cerevisiae within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn401

b:43.1
occ:1.00
 OQ2 C:KCX98 2.0 33.0 1.0
NE2 C:HIS180 2.2 29.6 1.0
ND1 C:HIS137 2.2 28.3 1.0
O2 C:URF403 2.5 29.1 1.0
CE1 C:HIS137 2.8 29.9 1.0
CX C:KCX98 3.0 32.6 1.0
CD2 C:HIS180 3.1 27.6 1.0
CE1 C:HIS180 3.2 29.5 1.0
ZN C:ZN402 3.4 31.4 1.0
OQ1 C:KCX98 3.4 32.3 1.0
CG C:HIS137 3.4 27.9 1.0
C2 C:URF403 3.7 41.0 1.0
CB C:HIS137 3.9 26.6 1.0
NE2 C:HIS137 4.1 29.7 1.0
CE1 C:HIS14 4.1 24.6 1.0
O C:LYS230 4.1 31.8 1.0
NZ C:KCX98 4.2 30.4 1.0
OD2 C:ASP258 4.2 34.1 1.0
ND1 C:HIS180 4.3 29.9 1.0
CG C:HIS180 4.3 28.7 1.0
NE2 C:HIS14 4.3 25.0 1.0
CD2 C:HIS137 4.4 27.9 1.0
N3 C:URF403 4.5 45.4 1.0
CE C:KCX98 4.6 26.7 1.0
CE1 C:TYR100 4.7 28.5 1.0
N1 C:URF403 4.7 43.1 1.0
CG C:ASP258 4.7 29.7 1.0
OD1 C:ASP258 4.7 28.1 1.0
CG2 C:THR105 4.8 34.2 1.0
CA C:HIS137 4.8 26.6 1.0

Zinc binding site 4 out of 8 in 6l0b

Go back to Zinc Binding Sites List in 6l0b
Zinc binding site 4 out of 8 in the Crystal Structure of Dihydroorotase in Complex with Fluorouracil From Saccharomyces Cerevisiae


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure of Dihydroorotase in Complex with Fluorouracil From Saccharomyces Cerevisiae within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn402

b:31.4
occ:1.00
 NE2 C:HIS16 2.1 22.2 1.0
OQ1 C:KCX98 2.2 32.3 1.0
NE2 C:HIS14 2.2 25.0 1.0
OD1 C:ASP258 2.2 28.1 1.0
O2 C:URF403 2.9 29.1 1.0
CD2 C:HIS16 3.0 22.5 1.0
CX C:KCX98 3.0 32.6 1.0
CG C:ASP258 3.0 29.7 1.0
CE1 C:HIS16 3.1 22.8 1.0
CE1 C:HIS14 3.1 24.6 1.0
CD2 C:HIS14 3.2 25.3 1.0
OQ2 C:KCX98 3.2 33.0 1.0
C2 C:URF403 3.2 41.0 1.0
N3 C:URF403 3.2 45.4 1.0
ZN C:ZN401 3.4 43.1 1.0
OD2 C:ASP258 3.5 34.1 1.0
CB C:ASP258 4.1 26.1 1.0
CG C:HIS16 4.2 23.8 1.0
ND1 C:HIS16 4.2 23.1 1.0
NZ C:KCX98 4.2 30.4 1.0
ND1 C:HIS14 4.3 24.9 1.0
CG C:HIS14 4.3 25.2 1.0
N1 C:URF403 4.4 43.1 1.0
C4 C:URF403 4.4 37.5 1.0
CD2 C:HIS180 4.4 27.6 1.0
NE2 C:HIS180 4.5 29.6 1.0
CG C:MET41 4.6 28.4 1.0
CA C:ASP258 4.6 24.3 1.0
OH C:TYR100 4.7 23.8 1.0

Zinc binding site 5 out of 8 in 6l0b

Go back to Zinc Binding Sites List in 6l0b
Zinc binding site 5 out of 8 in the Crystal Structure of Dihydroorotase in Complex with Fluorouracil From Saccharomyces Cerevisiae


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Crystal Structure of Dihydroorotase in Complex with Fluorouracil From Saccharomyces Cerevisiae within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn401

b:32.7
occ:1.00
 NE2 B:HIS14 2.1 23.1 1.0
OQ2 B:KCX98 2.2 39.0 1.0
OD1 B:ASP258 2.2 30.0 1.0
NE2 B:HIS16 2.3 27.4 1.0
N1 B:URF403 2.5 45.1 1.0
O2 B:URF403 2.8 29.9 1.0
C2 B:URF403 3.0 41.1 1.0
CG B:ASP258 3.0 29.1 1.0
CX B:KCX98 3.0 33.2 1.0
CE1 B:HIS14 3.1 25.1 1.0
CD2 B:HIS14 3.1 24.2 1.0
OQ1 B:KCX98 3.2 32.0 1.0
CE1 B:HIS16 3.2 25.2 1.0
CD2 B:HIS16 3.4 25.1 1.0
OD2 B:ASP258 3.4 29.2 1.0
ZN B:ZN402 3.4 39.7 1.0
C6 B:URF403 3.7 39.5 1.0
CB B:ASP258 4.1 26.3 1.0
ND1 B:HIS14 4.2 25.6 1.0
NZ B:KCX98 4.2 34.0 1.0
CG B:HIS14 4.2 26.1 1.0
CD2 B:HIS180 4.3 24.0 1.0
N3 B:URF403 4.3 49.7 1.0
ND1 B:HIS16 4.4 27.6 1.0
NE2 B:HIS180 4.4 23.8 1.0
CG B:HIS16 4.5 26.4 1.0
CG B:MET41 4.6 27.5 1.0
CA B:ASP258 4.6 25.6 1.0
OH B:TYR100 4.6 30.6 1.0
C5 B:URF403 4.8 38.5 1.0

Zinc binding site 6 out of 8 in 6l0b

Go back to Zinc Binding Sites List in 6l0b
Zinc binding site 6 out of 8 in the Crystal Structure of Dihydroorotase in Complex with Fluorouracil From Saccharomyces Cerevisiae


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Crystal Structure of Dihydroorotase in Complex with Fluorouracil From Saccharomyces Cerevisiae within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn402

b:39.7
occ:1.00
 NE2 B:HIS180 2.1 23.8 1.0
O2 B:URF403 2.1 29.9 1.0
OQ1 B:KCX98 2.1 32.0 1.0
ND1 B:HIS137 2.2 25.4 1.0
CE1 B:HIS137 3.0 25.6 1.0
CD2 B:HIS180 3.0 24.0 1.0
CE1 B:HIS180 3.1 22.9 1.0
CX B:KCX98 3.1 33.2 1.0
C2 B:URF403 3.2 41.1 1.0
CG B:HIS137 3.3 26.0 1.0
ZN B:ZN401 3.4 32.7 1.0
OQ2 B:KCX98 3.5 39.0 1.0
CB B:HIS137 3.8 26.7 1.0
N1 B:URF403 4.0 45.1 1.0
CE1 B:HIS14 4.1 25.1 1.0
NE2 B:HIS137 4.2 25.6 1.0
ND1 B:HIS180 4.2 23.4 1.0
O B:LYS230 4.2 29.4 1.0
CG B:HIS180 4.2 23.8 1.0
NZ B:KCX98 4.3 34.0 1.0
OD2 B:ASP258 4.3 29.2 1.0
CD2 B:HIS137 4.3 25.8 1.0
N3 B:URF403 4.3 49.7 1.0
NE2 B:HIS14 4.3 23.1 1.0
CE1 B:TYR100 4.5 27.4 1.0
CA B:HIS137 4.6 27.7 1.0
CE B:KCX98 4.7 29.3 1.0
CG2 B:THR105 4.7 31.1 1.0
CG B:ASP258 4.8 29.1 1.0
OD1 B:ASP258 4.9 30.0 1.0
OG1 B:THR105 4.9 33.8 1.0
CD B:PRO231 5.0 25.1 1.0
CD1 B:TYR100 5.0 26.6 1.0

Zinc binding site 7 out of 8 in 6l0b

Go back to Zinc Binding Sites List in 6l0b
Zinc binding site 7 out of 8 in the Crystal Structure of Dihydroorotase in Complex with Fluorouracil From Saccharomyces Cerevisiae


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 7 of Crystal Structure of Dihydroorotase in Complex with Fluorouracil From Saccharomyces Cerevisiae within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn401

b:59.2
occ:1.00
 OQ1 D:KCX98 2.0 55.2 1.0
O2 D:URF403 2.1 46.6 1.0
NE2 D:HIS180 2.2 40.3 1.0
ND1 D:HIS137 2.3 54.9 1.0
CX D:KCX98 3.1 51.4 1.0
CE1 D:HIS137 3.1 55.6 1.0
CD2 D:HIS180 3.1 40.6 1.0
CE1 D:HIS180 3.2 40.8 1.0
C2 D:URF403 3.3 55.4 1.0
OQ2 D:KCX98 3.4 50.8 1.0
CG D:HIS137 3.5 52.7 1.0
ZN D:ZN402 3.5 55.5 1.0
CB D:HIS137 3.9 48.4 1.0
O D:LYS230 4.0 44.9 1.0
OD2 D:ASP258 4.0 56.4 1.0
N3 D:URF403 4.2 57.9 1.0
CE1 D:HIS14 4.2 48.4 1.0
NZ D:KCX98 4.2 53.5 1.0
CG D:HIS180 4.2 41.5 1.0
N1 D:URF403 4.3 60.2 1.0
ND1 D:HIS180 4.3 40.5 1.0
NE2 D:HIS137 4.3 51.2 1.0
NE2 D:HIS14 4.3 47.9 1.0
CE1 D:TYR100 4.5 57.5 1.0
CD2 D:HIS137 4.5 50.8 1.0
CG D:ASP258 4.6 53.6 1.0
CE D:KCX98 4.7 55.1 1.0
OD1 D:ASP258 4.7 53.5 1.0
OG1 D:THR105 4.7 60.4 1.0
CG2 D:THR105 4.7 52.8 1.0
CA D:HIS137 4.8 46.4 1.0
C D:LYS230 5.0 40.0 1.0

Zinc binding site 8 out of 8 in 6l0b

Go back to Zinc Binding Sites List in 6l0b
Zinc binding site 8 out of 8 in the Crystal Structure of Dihydroorotase in Complex with Fluorouracil From Saccharomyces Cerevisiae


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 8 of Crystal Structure of Dihydroorotase in Complex with Fluorouracil From Saccharomyces Cerevisiae within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn402

b:55.5
occ:1.00
 OD1 D:ASP258 2.0 53.5 1.0
NE2 D:HIS16 2.1 49.3 1.0
NE2 D:HIS14 2.1 47.9 1.0
OQ2 D:KCX98 2.3 50.8 1.0
CG D:ASP258 2.8 53.6 1.0
O2 D:URF403 2.9 46.6 1.0
CD2 D:HIS14 3.0 49.5 1.0
CD2 D:HIS16 3.0 50.7 1.0
CE1 D:HIS16 3.1 46.4 1.0
CX D:KCX98 3.1 51.4 1.0
CE1 D:HIS14 3.2 48.4 1.0
OD2 D:ASP258 3.2 56.4 1.0
C2 D:URF403 3.3 55.4 1.0
N3 D:URF403 3.3 57.9 1.0
OQ1 D:KCX98 3.4 55.2 1.0
ZN D:ZN401 3.5 59.2 1.0
CB D:ASP258 3.9 46.9 1.0
CG D:HIS14 4.2 48.4 1.0
CG D:HIS16 4.2 51.4 1.0
ND1 D:HIS16 4.2 49.8 1.0
ND1 D:HIS14 4.2 48.4 1.0
NZ D:KCX98 4.3 53.5 1.0
CA D:ASP258 4.3 43.1 1.0
C4 D:URF403 4.4 59.1 1.0
N1 D:URF403 4.4 60.2 1.0
CD2 D:HIS180 4.4 40.6 1.0
NE2 D:HIS180 4.6 40.3 1.0
OH D:TYR100 4.6 53.3 1.0
CG D:MET41 4.6 53.7 1.0
C D:ASP258 4.9 42.4 1.0
O4 D:URF403 4.9 61.2 1.0
O D:ASP258 5.0 38.8 1.0

Reference:

H.H.Guan, Y.H.Huang, C.Y.Huang, C.J.Chen. Crystal Structure of Dihydroorotase From Saccharomyces Cerevisiae To Be Published.
Page generated: Tue Oct 29 02:11:50 2024

Last articles

Zn in 9J0N
Zn in 9J0O
Zn in 9J0P
Zn in 9FJX
Zn in 9EKB
Zn in 9C0F
Zn in 9CAH
Zn in 9CH0
Zn in 9CH3
Zn in 9CH1
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy