Zinc in PDB 6k2k: Solution Structure of MUL1-Ring Domain

All present enzymatic activity of Solution Structure of MUL1-Ring Domain:
2.3.2.27;

The binding sites of Zinc atom in the Solution Structure of MUL1-Ring Domain (pdb code 6k2k). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Solution Structure of MUL1-Ring Domain, PDB code: 6k2k:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Solution Structure of MUL1-Ring Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Solution Structure of MUL1-Ring Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn500 b:0.0 occ:1.00 SG A:CYS302 2.3 41.4 1.0 SG A:CYS326 2.3 12.1 1.0 SG A:CYS305 2.4 4.1 1.0 SG A:CYS323 2.4 60.3 1.0 HB2 A:CYS326 3.0 0.0 1.0 HB3 A:CYS305 3.1 0.0 1.0 HB3 A:CYS302 3.2 0.0 1.0 CB A:CYS326 3.2 12.1 1.0 HB3 A:CYS323 3.3 0.0 1.0 CB A:CYS302 3.3 40.0 1.0 OG A:SER308 3.3 60.1 1.0 CB A:CYS305 3.4 12.0 1.0 H A:CYS305 3.4 32.5 1.0 CB A:CYS323 3.4 11.1 1.0 HG A:SER308 3.5 31.4 1.0 HB2 A:CYS302 3.6 0.0 1.0 H A:CYS323 3.7 41.1 1.0 H A:CYS326 3.9 34.3 1.0 N A:CYS305 4.0 63.3 1.0 HB3 A:CYS326 4.0 0.0 1.0 N A:CYS323 4.1 5.2 1.0 HB A:VAL304 4.1 34.1 1.0 HB2 A:CYS305 4.2 0.0 1.0 CA A:CYS326 4.3 73.3 1.0 HG21 A:VAL304 4.3 0.0 1.0 CA A:CYS305 4.3 41.0 1.0 CA A:CYS323 4.3 1.2 1.0 HB2 A:CYS323 4.3 0.0 1.0 N A:CYS326 4.4 11.3 1.0 H A:SER308 4.4 22.5 1.0 HA A:CYS326 4.5 20.4 1.0 H A:LEU306 4.5 13.2 1.0 O A:CYS323 4.5 5.3 1.0 OG A:SER322 4.6 44.4 1.0 CB A:SER308 4.7 4.1 1.0 HA A:SER322 4.7 2.0 1.0 CA A:CYS302 4.8 52.2 1.0 H A:VAL304 4.8 43.2 1.0 C A:CYS323 4.8 1.3 1.0 O A:CYS302 5.0 13.5 1.0 CB A:VAL304 5.0 44.1 1.0 CG2 A:VAL304 5.0 53.5 1.0 HB2 A:GLU325 5.0 0.0 1.0

Zinc binding site 2 out of 2 in the Solution Structure of MUL1-Ring Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Solution Structure of MUL1-Ring Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn501 b:0.0 occ:1.00 ND1 A:HIS319 2.1 71.1 1.0 SG A:CYS317 2.3 24.3 1.0 SG A:CYS336 2.4 64.1 1.0 SG A:CYS339 2.4 23.4 1.0 HB2 A:HIS319 2.7 0.0 1.0 HB3 A:CYS339 3.1 0.0 1.0 CE1 A:HIS319 3.1 32.4 1.0 OE2 A:GLU316 3.1 71.3 1.0 CG A:HIS319 3.1 55.2 1.0 HB3 A:CYS336 3.3 0.0 1.0 CB A:CYS336 3.3 32.3 1.0 CB A:CYS339 3.3 74.3 1.0 HE1 A:HIS319 3.4 62.3 1.0 CB A:HIS319 3.4 11.4 1.0 CB A:CYS317 3.5 31.4 1.0 OE1 A:GLN341 3.6 63.4 1.0 HB2 A:CYS336 3.6 0.0 1.0 HB2 A:CYS317 3.7 0.0 1.0 HB3 A:CYS317 3.7 0.0 1.0 H A:CYS339 3.8 62.3 1.0 HB A:ILE338 4.0 73.4 1.0 HB3 A:HIS319 4.0 0.0 1.0 HB2 A:GLN341 4.1 0.0 1.0 H A:HIS319 4.1 73.1 1.0 HB2 A:CYS339 4.2 0.0 1.0 N A:CYS339 4.2 23.5 1.0 NE2 A:HIS319 4.3 24.3 1.0 CD A:GLU316 4.3 41.1 1.0 CD2 A:HIS319 4.3 41.0 1.0 CA A:CYS339 4.4 62.1 1.0 H A:CYS317 4.5 15.1 1.0 H A:GLN341 4.5 14.5 1.0 HB2 A:GLU316 4.6 0.0 1.0 CA A:HIS319 4.6 21.2 1.0 CD A:GLN341 4.7 1.1 1.0 N A:HIS319 4.7 34.3 1.0 H A:ILE338 4.7 1.2 1.0 HG12 A:ILE338 4.8 0.0 1.0 CA A:CYS336 4.8 71.4 1.0 HG3 A:GLU316 4.8 0.0 1.0 CA A:CYS317 4.8 43.0 1.0 CB A:ILE338 5.0 53.3 1.0 OE1 A:GLU316 5.0 20.1 1.0

M.S.Lee, S.O.Lee, M.K.Lee, G.S.Yi, C.K.Lee, K.S.Ryu, S.W.Chi. Solution Structure of MUL1-Ring Domain and Its Interaction with P53 Transactivation Domain. Biochem.Biophys.Res.Commun. V. 516 533 2019.
ISSN: ESSN 1090-2104
PubMed: 31235254
DOI: 10.1016/J.BBRC.2019.06.101