Zinc in PDB 6jqc: The Structural Basis of the Beta-Carbonic Anhydrase Cafc (Wild Type) of the Filamentous Fungus Aspergillus Fumigatus

All present enzymatic activity of The Structural Basis of the Beta-Carbonic Anhydrase Cafc (Wild Type) of the Filamentous Fungus Aspergillus Fumigatus:
4.2.1.1;

The structure of The Structural Basis of the Beta-Carbonic Anhydrase Cafc (Wild Type) of the Filamentous Fungus Aspergillus Fumigatus, PDB code: 6jqc was solved by M.S.Jin, S.Kim, N.J.Kim, S.Hong, S.Kim, J.Sung, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.07 / 1.80
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	42.575, 80.066, 48.791, 90.00, 115.84, 90.00
R / Rfree (%)	19.8 / 24.9

The binding sites of Zinc atom in the The Structural Basis of the Beta-Carbonic Anhydrase Cafc (Wild Type) of the Filamentous Fungus Aspergillus Fumigatus (pdb code 6jqc). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the The Structural Basis of the Beta-Carbonic Anhydrase Cafc (Wild Type) of the Filamentous Fungus Aspergillus Fumigatus, PDB code: 6jqc:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the The Structural Basis of the Beta-Carbonic Anhydrase Cafc (Wild Type) of the Filamentous Fungus Aspergillus Fumigatus


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Structural Basis of the Beta-Carbonic Anhydrase Cafc (Wild Type) of the Filamentous Fungus Aspergillus Fumigatus within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:18.1 occ:1.00 NE2 A:HIS88 2.1 22.8 1.0 O A:HOH371 2.2 16.4 1.0 SG A:CYS36 2.3 17.4 1.0 SG A:CYS91 2.3 21.6 1.0 CE1 A:HIS88 3.1 21.0 1.0 CD2 A:HIS88 3.1 21.8 1.0 CB A:CYS36 3.3 16.9 1.0 CB A:CYS91 3.3 21.2 1.0 CA A:CYS91 3.6 21.6 1.0 O A:HOH369 4.1 19.9 1.0 N A:GLY92 4.1 19.8 1.0 CB A:ASP38 4.1 19.2 1.0 OD2 A:ASP38 4.1 29.1 1.0 ND1 A:HIS88 4.2 20.1 1.0 CG A:HIS88 4.2 19.4 1.0 O B:HOH370 4.3 43.0 1.0 C A:CYS91 4.3 20.3 1.0 N A:GLY61 4.4 16.3 1.0 CA A:GLY61 4.5 17.4 1.0 CG A:ASP38 4.6 25.3 1.0 CA A:CYS36 4.7 16.8 1.0 N A:ASP38 4.8 17.1 1.0 CA A:ASP38 4.9 17.8 1.0 N A:CYS91 4.9 20.7 1.0 CG A:MET93 4.9 20.4 1.0

Zinc binding site 2 out of 2 in the The Structural Basis of the Beta-Carbonic Anhydrase Cafc (Wild Type) of the Filamentous Fungus Aspergillus Fumigatus


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Structural Basis of the Beta-Carbonic Anhydrase Cafc (Wild Type) of the Filamentous Fungus Aspergillus Fumigatus within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn201 b:19.2 occ:1.00 O B:HOH372 2.1 16.1 1.0 NE2 B:HIS88 2.1 18.8 1.0 SG B:CYS36 2.3 18.6 1.0 SG B:CYS91 2.4 22.6 1.0 CE1 B:HIS88 3.1 18.6 1.0 CD2 B:HIS88 3.1 19.4 1.0 CB B:CYS36 3.3 18.6 1.0 CB B:CYS91 3.4 21.8 1.0 CA B:CYS91 3.7 20.9 1.0 O B:HOH387 4.0 18.9 1.0 CB B:ASP38 4.0 21.8 1.0 OD2 B:ASP38 4.0 34.4 1.0 ND1 B:HIS88 4.2 17.5 1.0 N B:GLY92 4.2 20.3 1.0 CG B:HIS88 4.2 19.5 1.0 N B:GLY61 4.4 16.4 1.0 C B:CYS91 4.4 19.8 1.0 CA B:GLY61 4.4 17.7 1.0 CG B:ASP38 4.5 26.5 1.0 CA B:CYS36 4.7 18.7 1.0 N B:ASP38 4.8 17.8 1.0 CA B:ASP38 4.8 19.3 1.0 N B:CYS91 4.9 21.5 1.0 CG B:MET93 4.9 24.8 1.0

S.Kim, N.J.Kim, S.Hong, S.Kim, J.Sung, M.S.Jin. The Structural Basis of the Low Catalytic Activities of the Two Minor Beta-Carbonic Anhydrases of the Filamentous Fungus Aspergillus Fumigatus. J.Struct.Biol. V. 208 61 2019.
ISSN: ESSN 1095-8657
PubMed: 31376470
DOI: 10.1016/J.JSB.2019.07.011