Zinc in PDB 6h3r: Crystal Structure of SMAD2 Without Exon -MH1 Bound to the Cagac Site.

Protein crystallography data

The structure of Crystal Structure of SMAD2 Without Exon -MH1 Bound to the Cagac Site., PDB code: 6h3r was solved by Z.Kaczmarska, J.A.Marquez, M.J.Macias, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 27.80 / 2.75
Space group P 43 21 2
Cell size a, b, c (Å), α, β, γ (°) 80.140, 80.140, 143.840, 90.00, 90.00, 90.00
R / Rfree (%) 20.1 / 22.2

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of SMAD2 Without Exon -MH1 Bound to the Cagac Site. (pdb code 6h3r). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of SMAD2 Without Exon -MH1 Bound to the Cagac Site., PDB code: 6h3r:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 6h3r

Go back to Zinc Binding Sites List in 6h3r
Zinc binding site 1 out of 2 in the Crystal Structure of SMAD2 Without Exon -MH1 Bound to the Cagac Site.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of SMAD2 Without Exon -MH1 Bound to the Cagac Site. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn201

b:76.1
occ:1.00
ND1 A:HIS166 2.1 78.1 1.0
SG A:CYS74 2.3 69.1 1.0
SG A:CYS161 2.3 78.8 1.0
SG A:CYS149 2.3 83.2 1.0
CB A:CYS161 3.0 73.6 1.0
CG A:HIS166 3.1 76.2 1.0
CE1 A:HIS166 3.2 79.0 1.0
CB A:HIS166 3.3 72.2 1.0
CB A:CYS74 3.4 66.1 1.0
CB A:CYS149 3.5 83.8 1.0
CA A:CYS74 3.7 67.3 1.0
CA A:CYS149 3.8 86.8 1.0
CD2 A:HIS166 4.3 78.0 1.0
NE2 A:HIS166 4.3 79.4 1.0
C A:CYS149 4.4 89.9 1.0
CA A:CYS161 4.5 68.8 1.0
N A:GLU150 4.5 87.0 1.0
CB A:ASN163 4.6 66.6 1.0
N A:CYS74 4.7 72.3 1.0
N A:TYR151 4.7 82.0 1.0
N A:VAL75 4.8 69.6 1.0
C A:CYS74 4.8 73.0 1.0
CA A:HIS166 4.9 73.2 1.0
C A:TYR151 5.0 77.0 1.0

Zinc binding site 2 out of 2 in 6h3r

Go back to Zinc Binding Sites List in 6h3r
Zinc binding site 2 out of 2 in the Crystal Structure of SMAD2 Without Exon -MH1 Bound to the Cagac Site.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of SMAD2 Without Exon -MH1 Bound to the Cagac Site. within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn201

b:85.8
occ:1.00
SG B:CYS74 2.2 93.8 1.0
ND1 B:HIS166 2.2 88.7 1.0
SG B:CYS161 2.4 84.3 1.0
SG B:CYS149 2.4 84.8 1.0
CB B:CYS161 3.0 79.9 1.0
CG B:HIS166 3.2 85.8 1.0
CE1 B:HIS166 3.2 90.7 1.0
CB B:CYS149 3.3 85.7 1.0
CB B:CYS74 3.3 89.8 1.0
CB B:HIS166 3.4 80.1 1.0
CA B:CYS149 3.7 90.3 1.0
CA B:CYS74 3.7 89.2 1.0
C B:CYS149 4.3 96.1 1.0
NE2 B:HIS166 4.3 91.6 1.0
CD2 B:HIS166 4.3 89.4 1.0
N B:GLU150 4.4 94.8 1.0
CA B:CYS161 4.5 76.6 1.0
N B:TYR151 4.5 88.8 1.0
N B:CYS74 4.7 93.2 1.0
CB B:ASN163 4.7 81.9 1.0
C B:CYS74 4.8 93.6 1.0
N B:VAL75 4.8 86.1 1.0
C B:TYR151 4.9 87.4 1.0
N B:ALA152 4.9 86.3 1.0
CA B:HIS166 5.0 80.5 1.0
N B:CYS149 5.0 96.0 1.0

Reference:

L.Ruiz, Z.Kaczmarska, E.Aragon, T.Gomes, P.Martin Malpartida, N.De Martin Garrido, R.Freier, J.A.Marquez, M.J.Macias. Recognition of 5GC Dna Motifs Is Conserved in Bmp and Tgf-Beta Activated Smads To Be Published.
Page generated: Wed Dec 16 11:54:45 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy