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Zinc in PDB 6h3q: Crystal Structure of Human Carbonic Anhydrase II in Complex with the 4-(5-(Chloromethyl)-1,3-Selenazol-2-Yl)BenzenesulfonamideEnzymatic activity of Crystal Structure of Human Carbonic Anhydrase II in Complex with the 4-(5-(Chloromethyl)-1,3-Selenazol-2-Yl)Benzenesulfonamide
All present enzymatic activity of Crystal Structure of Human Carbonic Anhydrase II in Complex with the 4-(5-(Chloromethyl)-1,3-Selenazol-2-Yl)Benzenesulfonamide:
4.2.1.1; Protein crystallography data
The structure of Crystal Structure of Human Carbonic Anhydrase II in Complex with the 4-(5-(Chloromethyl)-1,3-Selenazol-2-Yl)Benzenesulfonamide, PDB code: 6h3q
was solved by
M.Ferraroni,
A.Angeli,
C.Supuran,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6h3q:
The structure of Crystal Structure of Human Carbonic Anhydrase II in Complex with the 4-(5-(Chloromethyl)-1,3-Selenazol-2-Yl)Benzenesulfonamide also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human Carbonic Anhydrase II in Complex with the 4-(5-(Chloromethyl)-1,3-Selenazol-2-Yl)Benzenesulfonamide
(pdb code 6h3q). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human Carbonic Anhydrase II in Complex with the 4-(5-(Chloromethyl)-1,3-Selenazol-2-Yl)Benzenesulfonamide, PDB code: 6h3q: Zinc binding site 1 out of 1 in 6h3qGo back to Zinc Binding Sites List in 6h3q
Zinc binding site 1 out
of 1 in the Crystal Structure of Human Carbonic Anhydrase II in Complex with the 4-(5-(Chloromethyl)-1,3-Selenazol-2-Yl)Benzenesulfonamide
Mono view Stereo pair view
Reference:
A.Angeli,
E.Trallori,
M.Ferraroni,
L.Di Cesare Mannelli,
C.Ghelardini,
C.T.Supuran.
Discovery of New 2, 5-Disubstituted 1,3-Selenazoles As Selective Human Carbonic Anhydrase IX Inhibitors with Potent Anti-Tumor Activity. Eur.J.Med.Chem. V. 157 1214 2018.
Page generated: Wed Dec 16 11:54:44 2020
ISSN: ISSN 0223-5234 PubMed: 30193219 DOI: 10.1016/J.EJMECH.2018.08.096 |
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