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Zinc in PDB 6gge: P53 Cancer Mutant Y220C in Complex with Small-Molecule Stabilizer PK9327Protein crystallography data
The structure of P53 Cancer Mutant Y220C in Complex with Small-Molecule Stabilizer PK9327, PDB code: 6gge
was solved by
A.C.Joerger,
M.R.Bauer,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the P53 Cancer Mutant Y220C in Complex with Small-Molecule Stabilizer PK9327
(pdb code 6gge). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the P53 Cancer Mutant Y220C in Complex with Small-Molecule Stabilizer PK9327, PDB code: 6gge: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 6ggeGo back to Zinc Binding Sites List in 6gge
Zinc binding site 1 out
of 2 in the P53 Cancer Mutant Y220C in Complex with Small-Molecule Stabilizer PK9327
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 6ggeGo back to Zinc Binding Sites List in 6gge
Zinc binding site 2 out
of 2 in the P53 Cancer Mutant Y220C in Complex with Small-Molecule Stabilizer PK9327
Mono view Stereo pair view
Reference:
M.R.Bauer,
R.N.Jones,
R.K.Tareque,
B.Springett,
F.A.Dingler,
L.Verduci,
K.J.Patel,
A.R.Fersht,
A.C.Joerger,
J.Spencer.
A Structure-Guided Molecular Chaperone Approach For Restoring the Transcriptional Activity of the P53 Cancer Mutant Y220C. Future Med Chem V. 11 2491 2019.
Page generated: Wed Dec 16 11:52:17 2020
ISSN: ISSN 1756-8927 PubMed: 31633398 DOI: 10.4155/FMC-2019-0181 |
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