Zinc in PDB 6g18: Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State C

All present enzymatic activity of Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State C:
2.7.11.1;

The binding sites of Zinc atom in the Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State C (pdb code 6g18). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State C, PDB code: 6g18:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State C


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State C within 5.0Å range: probe atom residue distance (Å) B Occ f:Zn200 b:0.5 occ:1.00 N f:CYS145 2.4 0.6 1.0 N f:LYS143 2.4 0.5 1.0 O f:CYS141 2.4 0.2 1.0 N f:CYS144 2.6 0.7 1.0 C f:LYS143 3.1 0.2 1.0 C f:GLY142 3.1 0.7 1.0 C f:CYS141 3.1 1.0 1.0 CA f:CYS145 3.1 0.8 1.0 CA f:GLY142 3.2 0.3 1.0 CA f:LYS143 3.2 0.9 1.0 C f:CYS144 3.3 0.4 1.0 N f:GLY142 3.4 0.5 1.0 CA f:CYS144 3.5 0.2 1.0 OH f:TYR140 3.9 0.6 1.0 SG f:CYS145 3.9 0.1 1.0 O f:LYS143 3.9 0.0 1.0 CB f:CYS145 4.1 0.9 1.0 O f:GLY142 4.1 0.3 1.0 CZ f:TYR140 4.1 0.4 1.0 SG f:CYS141 4.2 0.5 1.0 CA f:CYS141 4.3 0.6 1.0 CB f:CYS141 4.3 0.8 1.0 C f:CYS145 4.3 0.1 1.0 CE1 f:TYR140 4.3 0.0 1.0 N f:LEU146 4.3 0.3 1.0 O f:CYS144 4.5 0.4 1.0 CB f:LYS143 4.5 0.0 1.0 SG f:CYS144 4.5 0.5 1.0 CB f:CYS144 4.6 0.3 1.0 CE2 f:TYR140 4.8 0.0 1.0 N f:CYS141 5.0 0.9 1.0

Zinc binding site 2 out of 2 in the Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State C


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State C within 5.0Å range: probe atom residue distance (Å) B Occ y:Zn500 b:20.9 occ:1.00 SG y:CYS273 2.1 41.6 1.0 SG y:CYS270 2.3 33.9 1.0 SG y:CYS285 2.5 49.2 1.0 SG y:CYS288 2.7 54.9 1.0 CB y:CYS270 3.2 32.6 1.0 CB y:CYS273 3.4 40.5 1.0 CB y:CYS285 3.5 48.6 1.0 N y:CYS288 3.5 54.5 1.0 CB y:CYS288 3.7 52.5 1.0 N y:CYS273 4.0 37.5 1.0 CA y:CYS288 4.1 51.0 1.0 CB y:HIS287 4.1 75.2 1.0 CA y:CYS273 4.2 39.6 1.0 C y:HIS287 4.6 60.9 1.0 CA y:CYS270 4.6 31.7 1.0 CA y:HIS287 4.7 65.4 1.0 C y:CYS288 4.8 47.5 1.0 CD2 y:HIS287 4.8 90.0 1.0 N y:GLY289 4.8 46.2 1.0 N y:HIS287 4.8 66.2 1.0 CG y:HIS287 4.9 87.2 1.0 CG2 y:THR292 4.9 47.2 1.0 C y:CYS273 4.9 41.7 1.0 CA y:CYS285 4.9 51.2 1.0 N y:PHE274 4.9 41.8 1.0

M.Ameismeier, J.Cheng, O.Berninghausen, R.Beckmann. Visualizing Late States of Human 40S Ribosomal Subunit Maturation. Nature V. 558 249 2018.
ISSN: ISSN 0028-0836
PubMed: 29875412
DOI: 10.1038/S41586-018-0193-0