Zinc in PDB 6fzt: Crystal Structure of SMAD8_9-MH1 Bound to the Ggcgc Site.

The structure of Crystal Structure of SMAD8_9-MH1 Bound to the Ggcgc Site., PDB code: 6fzt was solved by Z.Kaczmarska, J.A.Marquez, M.J.Macias, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	59.11 / 2.46
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	75.433, 79.509, 88.372, 90.00, 90.00, 90.00
R / Rfree (%)	19.3 / 23.7

The binding sites of Zinc atom in the Crystal Structure of SMAD8_9-MH1 Bound to the Ggcgc Site. (pdb code 6fzt). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of SMAD8_9-MH1 Bound to the Ggcgc Site., PDB code: 6fzt:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of SMAD8_9-MH1 Bound to the Ggcgc Site.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of SMAD8_9-MH1 Bound to the Ggcgc Site. within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:52.4 occ:1.00 ND1 A:HIS127 2.0 49.3 1.0 SG A:CYS110 2.3 52.2 1.0 SG A:CYS65 2.4 54.8 1.0 SG A:CYS122 2.5 52.4 1.0 CE1 A:HIS127 3.0 49.1 1.0 CG A:HIS127 3.1 48.0 1.0 CB A:CYS122 3.2 48.4 1.0 CB A:CYS110 3.3 50.9 1.0 CB A:HIS127 3.5 45.2 1.0 CB A:CYS65 3.5 50.6 1.0 CA A:CYS110 3.5 53.2 1.0 CA A:CYS65 3.7 50.1 1.0 N A:GLU111 4.1 51.2 1.0 NE2 A:HIS127 4.1 49.5 1.0 CD2 A:HIS127 4.2 48.9 1.0 C A:CYS110 4.3 57.6 1.0 N A:PHE112 4.5 45.1 1.0 N A:CYS65 4.5 51.7 1.0 N A:CYS110 4.7 55.5 1.0 CA A:CYS122 4.7 47.2 1.0 C A:CYS65 4.9 55.2 1.0 N A:VAL66 4.9 49.9 1.0 CB A:ASN124 4.9 32.5 1.0 CA A:HIS127 5.0 45.6 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of SMAD8_9-MH1 Bound to the Ggcgc Site.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of SMAD8_9-MH1 Bound to the Ggcgc Site. within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn201 b:53.9 occ:1.00 ND1 B:HIS127 2.0 52.4 1.0 SG B:CYS122 2.3 54.1 1.0 SG B:CYS110 2.4 48.0 1.0 SG B:CYS65 2.5 61.5 1.0 CE1 B:HIS127 3.0 53.0 1.0 CB B:CYS122 3.0 48.7 1.0 CG B:HIS127 3.1 50.5 1.0 CB B:CYS110 3.4 47.6 1.0 CB B:HIS127 3.4 46.4 1.0 CB B:CYS65 3.5 57.7 1.0 CA B:CYS110 3.6 49.4 1.0 CA B:CYS65 3.7 57.8 1.0 NE2 B:HIS127 4.1 53.7 1.0 CD2 B:HIS127 4.2 52.8 1.0 N B:GLU111 4.2 49.1 1.0 C B:CYS110 4.4 53.8 1.0 CA B:CYS122 4.5 45.9 1.0 N B:PHE112 4.5 46.9 1.0 N B:CYS65 4.5 61.8 1.0 N B:CYS110 4.7 52.9 1.0 C B:CYS65 4.8 55.9 1.0 N B:VAL66 4.8 49.1 1.0 CB B:ASN124 4.8 39.5 1.0 CA B:HIS127 4.9 47.4 1.0 C B:PHE112 5.0 49.1 1.0

L.Ruiz, Z.Kaczmarska, E.Aragon, J.Cordero, P.Martin Malpartida, R.Freier, J.A.Marquez, M.J.Macias. Recognition of the 5GC Dna Motif Is Conserved in Bmp and Tgf-Beta Activated Smad Proteins To Be Published.