Zinc in PDB 6eec: Mycobacterium Tuberculosis Rnap Promoter Unwinding Intermediate Complex with Rbpa/Card and AP3 Promoter Captured By Corallopyronin

All present enzymatic activity of Mycobacterium Tuberculosis Rnap Promoter Unwinding Intermediate Complex with Rbpa/Card and AP3 Promoter Captured By Corallopyronin:
2.7.7.6;

The structure of Mycobacterium Tuberculosis Rnap Promoter Unwinding Intermediate Complex with Rbpa/Card and AP3 Promoter Captured By Corallopyronin also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the Mycobacterium Tuberculosis Rnap Promoter Unwinding Intermediate Complex with Rbpa/Card and AP3 Promoter Captured By Corallopyronin (pdb code 6eec). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Mycobacterium Tuberculosis Rnap Promoter Unwinding Intermediate Complex with Rbpa/Card and AP3 Promoter Captured By Corallopyronin, PDB code: 6eec:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Mycobacterium Tuberculosis Rnap Promoter Unwinding Intermediate Complex with Rbpa/Card and AP3 Promoter Captured By Corallopyronin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Mycobacterium Tuberculosis Rnap Promoter Unwinding Intermediate Complex with Rbpa/Card and AP3 Promoter Captured By Corallopyronin within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn2000 b:94.2 occ:1.00 SG D:CYS968 2.3 78.1 1.0 SG D:CYS978 2.3 75.6 1.0 SG D:CYS975 2.4 73.3 1.0 SG D:CYS891 2.4 76.8 1.0 CB D:CYS968 2.6 78.1 1.0 CA D:CYS968 2.7 78.1 1.0 CB D:CYS978 2.8 75.6 1.0 CB D:CYS891 3.5 76.8 1.0 CB D:CYS975 3.5 73.3 1.0 N D:ALA969 3.5 76.8 1.0 C D:CYS968 3.6 78.1 1.0 N D:CYS968 4.0 78.1 1.0 N D:CYS975 4.1 73.3 1.0 CA D:CYS978 4.2 75.6 1.0 CA D:CYS975 4.3 73.3 1.0 N D:CYS978 4.4 75.6 1.0 N D:CYS891 4.5 76.8 1.0 CA D:CYS891 4.6 76.8 1.0 O D:CYS968 4.6 78.1 1.0 O D:THR967 4.7 76.6 1.0 CG2 D:THR893 4.7 82.2 1.0 N D:THR970 4.8 77.4 1.0 C D:THR967 4.8 76.6 1.0 C D:CYS975 4.9 73.3 1.0 CA D:ALA969 4.9 76.8 1.0 CG2 D:THR970 4.9 77.4 1.0

Zinc binding site 2 out of 2 in the Mycobacterium Tuberculosis Rnap Promoter Unwinding Intermediate Complex with Rbpa/Card and AP3 Promoter Captured By Corallopyronin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Mycobacterium Tuberculosis Rnap Promoter Unwinding Intermediate Complex with Rbpa/Card and AP3 Promoter Captured By Corallopyronin within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn2001 b:0.0 occ:1.00 N D:CYS62 2.1 98.2 1.0 SG D:CYS78 2.3 91.6 1.0 SG D:CYS60 2.4 98.1 1.0 SG D:CYS62 2.5 98.2 1.0 N D:TYR61 2.6 89.6 1.0 CB D:CYS78 2.7 91.6 1.0 CB D:CYS60 2.7 98.1 1.0 CA D:CYS62 2.9 98.2 1.0 C D:TYR61 3.0 89.6 1.0 N D:GLY63 3.0 98.0 1.0 CB D:CYS62 3.1 98.2 1.0 C D:CYS60 3.1 98.1 1.0 CA D:TYR61 3.2 89.6 1.0 C D:CYS62 3.4 98.2 1.0 CA D:CYS60 3.5 98.1 1.0 CB D:TYR61 4.0 89.6 1.0 O D:CYS60 4.0 98.1 1.0 O D:TYR61 4.1 89.6 1.0 N D:LYS64 4.1 94.7 1.0 CA D:CYS78 4.1 91.6 1.0 CA D:GLY63 4.2 98.0 1.0 SG D:CYS75 4.2 94.3 1.0 CB D:CYS75 4.4 94.3 1.0 O D:CYS62 4.5 98.2 1.0 N D:CYS60 4.5 98.1 1.0 N D:CYS78 4.6 91.6 1.0 C D:GLY63 4.7 98.0 1.0 C D:CYS78 5.0 91.6 1.0

H.Boyaci, J.Chen, R.Jansen, S.A.Darst, E.A.Campbell. Structures of An Rna Polymerase Promoter Melting Intermediate Elucidate Dna Unwinding. Nature V. 565 382 2019.
ISSN: ESSN 1476-4687
PubMed: 30626968
DOI: 10.1038/S41586-018-0840-5