Zinc in PDB 6e1h: Structure of 2:1 Human PTCH1-Shh-N Complex

The structure of Structure of 2:1 Human PTCH1-Shh-N Complex also contains other interesting chemical elements:

Calcium

(Ca)

2 atoms

The binding sites of Zinc atom in the Structure of 2:1 Human PTCH1-Shh-N Complex (pdb code 6e1h). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of 2:1 Human PTCH1-Shh-N Complex, PDB code: 6e1h:

Zinc binding site 1 out of 1 in the Structure of 2:1 Human PTCH1-Shh-N Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of 2:1 Human PTCH1-Shh-N Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn201 b:71.1 occ:1.00 OD1 C:ASP147 2.3 69.9 1.0 OD2 C:ASP147 2.4 69.9 1.0 OE1 C:GLU176 2.6 60.4 1.0 CG C:ASP147 2.7 69.9 1.0 CE1 C:HIS140 2.9 81.4 1.0 ND1 C:HIS182 3.2 64.5 1.0 CE1 C:HIS180 3.6 61.4 1.0 NE2 C:HIS140 3.6 81.4 1.0 CD C:GLU176 3.6 60.4 1.0 CD2 C:HIS134 3.7 88.0 1.0 ND1 C:HIS140 3.9 81.4 1.0 OE2 C:GLU176 3.9 60.4 1.0 CG C:HIS182 3.9 64.5 1.0 CB C:HIS182 3.9 64.5 1.0 CE1 C:HIS182 4.1 64.5 1.0 CB C:ASP147 4.1 69.9 1.0 NE2 C:HIS134 4.2 88.0 1.0 ND1 C:HIS180 4.3 61.4 1.0 NE2 C:HIS180 4.5 61.4 1.0 CA C:HIS182 4.7 64.5 1.0 CD2 C:HIS140 4.8 81.4 1.0 CG C:HIS134 4.9 88.0 1.0 CG C:HIS140 4.9 81.4 1.0 CG C:GLU176 5.0 60.4 1.0

X.Qi, P.Schmiege, E.Coutavas, X.Li. Two Patched Molecules Engage Distinct Sites on Hedgehog Yielding A Signaling-Competent Complex. Science V. 362 2018.
ISSN: ESSN 1095-9203
PubMed: 30139912
DOI: 10.1126/SCIENCE.AAS8843