|
Zinc in PDB 6ck3: Co-Crytsal Structure of MNK2 in Complex with An InhibitorEnzymatic activity of Co-Crytsal Structure of MNK2 in Complex with An Inhibitor
All present enzymatic activity of Co-Crytsal Structure of MNK2 in Complex with An Inhibitor:
2.7.11.1; Protein crystallography data
The structure of Co-Crytsal Structure of MNK2 in Complex with An Inhibitor, PDB code: 6ck3
was solved by
Q.Han,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6ck3:
The structure of Co-Crytsal Structure of MNK2 in Complex with An Inhibitor also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Co-Crytsal Structure of MNK2 in Complex with An Inhibitor
(pdb code 6ck3). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Co-Crytsal Structure of MNK2 in Complex with An Inhibitor, PDB code: 6ck3: Zinc binding site 1 out of 1 in 6ck3Go back to Zinc Binding Sites List in 6ck3
Zinc binding site 1 out
of 1 in the Co-Crytsal Structure of MNK2 in Complex with An Inhibitor
Mono view Stereo pair view
Reference:
S.H.Reich,
P.A.Sprengeler,
G.G.Chiang,
J.R.Appleman,
J.Chen,
J.Clarine,
B.Eam,
J.T.Ernst,
Q.Han,
V.K.Goel,
E.Z.R.Han,
V.Huang,
I.N.J.Hung,
A.Jemison,
K.A.Jessen,
J.Molter,
D.Murphy,
M.Neal,
G.S.Parker,
M.Shaghafi,
S.Sperry,
J.Staunton,
C.R.Stumpf,
P.A.Thompson,
C.Tran,
S.E.Webber,
C.J.Wegerski,
H.Zheng,
K.R.Webster.
Structure-Based Design of Pyridone-Aminal EFT508 Targeting Dysregulated Translation By Selective Mitogen-Activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition. J. Med. Chem. V. 61 3516 2018.
Page generated: Wed Dec 16 11:36:49 2020
ISSN: ISSN 1520-4804 PubMed: 29526098 DOI: 10.1021/ACS.JMEDCHEM.7B01795 |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |