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Zinc in PDB 6bnb: Crystal Structure of DDB1-Crbn-BRD4(BD1) Complex Bound to DBET57 ProtacProtein crystallography data
The structure of Crystal Structure of DDB1-Crbn-BRD4(BD1) Complex Bound to DBET57 Protac, PDB code: 6bnb
was solved by
R.P.Nowak,
S.L.Deangelo,
D.Buckley,
M.Ishoey,
Z.He,
T.Zhang,
J.E.Bradner,
E.S.Fischer,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of DDB1-Crbn-BRD4(BD1) Complex Bound to DBET57 Protac
(pdb code 6bnb). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of DDB1-Crbn-BRD4(BD1) Complex Bound to DBET57 Protac, PDB code: 6bnb: Zinc binding site 1 out of 1 in 6bnbGo back to Zinc Binding Sites List in 6bnb
Zinc binding site 1 out
of 1 in the Crystal Structure of DDB1-Crbn-BRD4(BD1) Complex Bound to DBET57 Protac
Mono view Stereo pair view
Reference:
R.P.Nowak,
S.L.Deangelo,
D.Buckley,
Z.He,
K.A.Donovan,
J.An,
N.Safaee,
M.P.Jedrychowski,
C.M.Ponthier,
M.Ishoey,
T.Zhang,
J.D.Mancias,
N.S.Gray,
J.E.Bradner,
E.S.Fischer.
Plasticity in Binding Confers Selectivity in Ligand-Induced Protein Degradation. Nat. Chem. Biol. V. 14 706 2018.
Page generated: Wed Dec 16 11:32:45 2020
ISSN: ESSN 1552-4469 PubMed: 29892083 DOI: 10.1038/S41589-018-0055-Y |
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