Zinc in PDB 5zxw: Crystal Structure of Human Carbonic Anhydrase II Crystallized By Ammonium Sulfate

All present enzymatic activity of Crystal Structure of Human Carbonic Anhydrase II Crystallized By Ammonium Sulfate:
4.2.1.1;

The structure of Crystal Structure of Human Carbonic Anhydrase II Crystallized By Ammonium Sulfate, PDB code: 5zxw was solved by M.Kitahara, S.Fudo, T.Yoneda, M.Nukaga, T.Hoshino, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	34.97 / 1.32
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	42.102, 41.323, 72.130, 90.00, 104.19, 90.00
R / Rfree (%)	17.1 / 19.8

The binding sites of Zinc atom in the Crystal Structure of Human Carbonic Anhydrase II Crystallized By Ammonium Sulfate (pdb code 5zxw). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human Carbonic Anhydrase II Crystallized By Ammonium Sulfate, PDB code: 5zxw:

Zinc binding site 1 out of 1 in the Crystal Structure of Human Carbonic Anhydrase II Crystallized By Ammonium Sulfate


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human Carbonic Anhydrase II Crystallized By Ammonium Sulfate within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:12.0 occ:1.00 O A:HOH455 2.0 17.7 1.0 NE2 A:HIS94 2.0 9.7 1.0 ND1 A:HIS119 2.0 10.6 1.0 NE2 A:HIS96 2.1 10.3 1.0 O A:HOH657 2.9 25.0 1.0 CE1 A:HIS119 2.9 11.3 1.0 CE1 A:HIS94 3.0 11.2 1.0 CD2 A:HIS94 3.0 10.9 1.0 CE1 A:HIS96 3.0 13.0 1.0 CD2 A:HIS96 3.1 11.6 1.0 CG A:HIS119 3.1 10.3 1.0 CB A:HIS119 3.5 10.1 1.0 O A:HOH563 3.7 25.1 1.0 O A:HOH630 3.7 24.4 1.0 OG1 A:THR198 3.8 12.6 1.0 OE1 A:GLU106 4.0 12.2 1.0 ND1 A:HIS94 4.1 12.1 1.0 NE2 A:HIS119 4.1 11.0 1.0 CG A:HIS94 4.1 12.3 1.0 ND1 A:HIS96 4.2 11.6 1.0 CD2 A:HIS119 4.2 11.0 1.0 CG A:HIS96 4.2 10.0 1.0 O A:HOH679 4.5 23.6 1.0 CD A:GLU106 4.9 12.7 1.0 CA A:HIS119 5.0 10.1 1.0

M.Kitahara, S.Fudo, T.Yoneda, M.Nukaga, T.Hoshino. Anisotropic Distribution of Ammonium Sulfate Ions in Protein Crystallization Cryst.Growth Des. V. 19 6004 2019.
ISSN: ESSN 1528-7505
DOI: 10.1021/ACS.CGD.9B00256