Zinc in PDB 5zb3: Dimeric Crystal Structure of ORF57 From Kshv

The structure of Dimeric Crystal Structure of ORF57 From Kshv, PDB code: 5zb3 was solved by Z.Q.Gao, F.Yuan, Y.H.Dong, K.Lan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.15 / 3.51
Space group	P 64 2 2
Cell size a, b, c (Å), α, β, γ (°)	167.529, 167.529, 227.632, 90.00, 90.00, 120.00
R / Rfree (%)	25.7 / 30.6

The binding sites of Zinc atom in the Dimeric Crystal Structure of ORF57 From Kshv (pdb code 5zb3). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Dimeric Crystal Structure of ORF57 From Kshv, PDB code: 5zb3:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Dimeric Crystal Structure of ORF57 From Kshv


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Dimeric Crystal Structure of ORF57 From Kshv within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn500 b:92.9 occ:1.00 NE2 A:HIS423 2.1 92.8 1.0 SG A:CYS432 2.3 82.9 1.0 SG A:CYS427 2.3 0.4 1.0 SG A:CYS333 2.4 94.1 1.0 CE1 A:HIS423 3.0 0.6 1.0 CD2 A:HIS423 3.2 84.9 1.0 CB A:CYS333 3.2 0.2 1.0 CB A:CYS432 3.3 87.5 1.0 CB A:CYS427 3.4 0.3 1.0 O A:CYS333 3.7 0.3 1.0 C A:CYS333 3.9 95.7 1.0 ND1 A:HIS423 4.1 0.4 1.0 CA A:CYS333 4.2 0.2 1.0 CG A:HIS423 4.3 86.5 1.0 N A:VAL334 4.4 97.8 1.0 CE1 A:HIS424 4.5 96.9 1.0 CA A:CYS432 4.7 92.1 1.0 CG2 A:VAL334 4.8 79.4 1.0 ND1 A:HIS424 4.8 0.5 1.0 CA A:VAL334 4.8 81.0 1.0 CA A:CYS427 4.8 1.0 1.0 CB A:ASN429 5.0 0.7 1.0 O A:CYS427 5.0 0.6 1.0

Zinc binding site 2 out of 2 in the Dimeric Crystal Structure of ORF57 From Kshv


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Dimeric Crystal Structure of ORF57 From Kshv within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn500 b:78.7 occ:1.00 NE2 B:HIS423 2.0 89.1 1.0 SG B:CYS333 2.3 89.2 1.0 SG B:CYS432 2.3 91.2 1.0 SG B:CYS427 2.3 97.1 1.0 CE1 B:HIS423 2.8 0.3 1.0 CD2 B:HIS423 3.0 79.6 1.0 CB B:CYS427 3.1 84.5 1.0 CB B:CYS432 3.3 85.2 1.0 CB B:CYS333 3.3 77.8 1.0 ND1 B:HIS423 3.9 1.0 1.0 CG B:HIS423 4.0 81.4 1.0 C B:CYS333 4.2 79.9 1.0 O B:CYS333 4.2 0.9 1.0 CA B:CYS333 4.3 78.7 1.0 CE1 B:HIS424 4.5 0.5 1.0 CA B:CYS427 4.6 89.6 1.0 N B:VAL334 4.6 79.0 1.0 CA B:CYS432 4.7 94.1 1.0 CB B:ASN429 4.8 90.5 1.0 ND1 B:HIS424 4.8 0.7 1.0 O B:CYS427 4.9 0.8 1.0 CG2 B:VAL334 5.0 77.6 1.0

F.Yuan, Z.Q.Gao, V.Majerciak, L.Bai, M.L.Hu, X.X.Lin, Z.M.Zheng, Y.H.Dong, K.Lan. The Crystal Structure of Kshv ORF57 Reveals Dimeric Active Sites Important For Protein Stability and Function. Plos Pathog. V. 14 07232 2018.
ISSN: ESSN 1553-7374
PubMed: 30096191
DOI: 10.1371/JOURNAL.PPAT.1007232