Zinc in PDB 5x6h: Crystal Structure of SMAD5-MH1/Gc-Bre Dna Complex

The structure of Crystal Structure of SMAD5-MH1/Gc-Bre Dna Complex, PDB code: 5x6h was solved by N.Chai, J.Wang, Z.X.Wang, J.W.Wu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.43 / 3.10
Space group	P 64 2 2
Cell size a, b, c (Å), α, β, γ (°)	92.867, 92.867, 83.709, 90.00, 90.00, 120.00
R / Rfree (%)	20.2 / 23.1

The binding sites of Zinc atom in the Crystal Structure of SMAD5-MH1/Gc-Bre Dna Complex (pdb code 5x6h). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of SMAD5-MH1/Gc-Bre Dna Complex, PDB code: 5x6h:

Zinc binding site 1 out of 1 in the Crystal Structure of SMAD5-MH1/Gc-Bre Dna Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of SMAD5-MH1/Gc-Bre Dna Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn201 b:89.8 occ:1.00 ND1 B:HIS127 1.9 90.9 1.0 SG B:CYS122 2.3 97.5 1.0 SG B:CYS65 2.4 0.2 1.0 CE1 B:HIS127 2.5 96.2 1.0 SG B:CYS110 2.5 87.7 1.0 CB B:CYS122 3.0 94.3 1.0 CG B:HIS127 3.0 93.7 1.0 CB B:CYS110 3.2 94.0 1.0 CB B:CYS65 3.6 0.5 1.0 CA B:CYS110 3.6 99.4 1.0 NE2 B:HIS127 3.6 0.3 1.0 CB B:HIS127 3.7 89.9 1.0 CA B:CYS65 3.9 0.7 1.0 CD2 B:HIS127 3.9 0.9 1.0 N B:GLU111 4.1 0.4 1.0 C B:CYS110 4.4 0.1 1.0 CA B:CYS122 4.5 88.1 1.0 N B:CYS65 4.7 0.8 1.0 N B:PHE112 4.7 0.9 1.0 N B:CYS110 4.8 0.5 1.0 CB B:ASN124 4.9 95.8 1.0

N.Chai, W.X.Li, J.Wang, Z.X.Wang, S.M.Yang, J.W.Wu. Structural Basis For the SMAD5 MH1 Domain to Recognize Different Dna Sequences. Nucleic Acids Res. V. 43 9051 2015.
ISSN: ESSN 1362-4962
PubMed: 26304548
DOI: 10.1093/NAR/GKV848