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Zinc in PDB 5vv3: Structure of Human Neuronal Nitric Oxide Synthase Heme Domain in Complex with 4-(2-(((2-Aminoquinolin-7-Yl)Methyl)Amino)Ethyl) BenzonitrileEnzymatic activity of Structure of Human Neuronal Nitric Oxide Synthase Heme Domain in Complex with 4-(2-(((2-Aminoquinolin-7-Yl)Methyl)Amino)Ethyl) Benzonitrile
All present enzymatic activity of Structure of Human Neuronal Nitric Oxide Synthase Heme Domain in Complex with 4-(2-(((2-Aminoquinolin-7-Yl)Methyl)Amino)Ethyl) Benzonitrile:
1.14.13.39; Protein crystallography data
The structure of Structure of Human Neuronal Nitric Oxide Synthase Heme Domain in Complex with 4-(2-(((2-Aminoquinolin-7-Yl)Methyl)Amino)Ethyl) Benzonitrile, PDB code: 5vv3
was solved by
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5vv3:
The structure of Structure of Human Neuronal Nitric Oxide Synthase Heme Domain in Complex with 4-(2-(((2-Aminoquinolin-7-Yl)Methyl)Amino)Ethyl) Benzonitrile also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of Human Neuronal Nitric Oxide Synthase Heme Domain in Complex with 4-(2-(((2-Aminoquinolin-7-Yl)Methyl)Amino)Ethyl) Benzonitrile
(pdb code 5vv3). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Human Neuronal Nitric Oxide Synthase Heme Domain in Complex with 4-(2-(((2-Aminoquinolin-7-Yl)Methyl)Amino)Ethyl) Benzonitrile, PDB code: 5vv3: Zinc binding site 1 out of 1 in 5vv3Go back to Zinc Binding Sites List in 5vv3
Zinc binding site 1 out
of 1 in the Structure of Human Neuronal Nitric Oxide Synthase Heme Domain in Complex with 4-(2-(((2-Aminoquinolin-7-Yl)Methyl)Amino)Ethyl) Benzonitrile
Mono view Stereo pair view
Reference:
A.V.Pensa,
M.A.Cinelli,
H.Li,
G.Chreifi,
P.Mukherjee,
L.J.Roman,
P.Martasek,
T.L.Poulos,
R.B.Silverman.
Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines As Improved Human Neuronal Nitric Oxide Synthase Inhibitors. J. Med. Chem. V. 60 7146 2017.
Page generated: Wed Dec 16 11:12:59 2020
ISSN: ISSN 1520-4804 PubMed: 28776992 DOI: 10.1021/ACS.JMEDCHEM.7B00835 |
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