Zinc in PDB 5vnj: Crystal Structure of SEC23A/SEC24A/SEC22 Complexed with A C-Terminal Ff Sorting Motif (Ergic-53)

The structure of Crystal Structure of SEC23A/SEC24A/SEC22 Complexed with A C-Terminal Ff Sorting Motif (Ergic-53), PDB code: 5vnj was solved by W.Ma, J.Goldberg, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.83 / 2.81
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	147.955, 96.978, 129.549, 90.00, 90.22, 90.00
R / Rfree (%)	22.1 / 26.1

The binding sites of Zinc atom in the Crystal Structure of SEC23A/SEC24A/SEC22 Complexed with A C-Terminal Ff Sorting Motif (Ergic-53) (pdb code 5vnj). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of SEC23A/SEC24A/SEC22 Complexed with A C-Terminal Ff Sorting Motif (Ergic-53), PDB code: 5vnj:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of SEC23A/SEC24A/SEC22 Complexed with A C-Terminal Ff Sorting Motif (Ergic-53)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of SEC23A/SEC24A/SEC22 Complexed with A C-Terminal Ff Sorting Motif (Ergic-53) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn801 b:77.3 occ:1.00 SG A:CYS85 2.3 65.4 1.0 SG A:CYS61 2.4 79.1 1.0 SG A:CYS88 2.4 76.4 1.0 SG A:CYS66 2.5 83.9 1.0 CB A:CYS85 3.1 68.9 1.0 CB A:CYS66 3.1 88.7 1.0 CB A:CYS61 3.1 76.1 1.0 CB A:CYS88 3.7 80.4 1.0 N A:CYS88 4.1 77.6 1.0 N A:ARG67 4.2 88.2 1.0 N A:ALA68 4.3 79.3 1.0 CA A:CYS88 4.4 80.5 1.0 CB A:GLN90 4.4 93.7 1.0 CA A:CYS66 4.5 91.1 1.0 CA A:CYS85 4.6 68.9 1.0 CB A:ARG63 4.6 90.6 1.0 C A:CYS66 4.6 89.1 1.0 CB A:ALA68 4.6 76.1 1.0 CA A:CYS61 4.6 75.7 1.0 CB A:PHE87 4.8 72.5 1.0 C A:CYS88 5.0 83.9 1.0 N A:GLN90 5.0 88.5 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of SEC23A/SEC24A/SEC22 Complexed with A C-Terminal Ff Sorting Motif (Ergic-53)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of SEC23A/SEC24A/SEC22 Complexed with A C-Terminal Ff Sorting Motif (Ergic-53) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1101 b:0.9 occ:1.00 SG B:CYS452 2.3 70.3 1.0 SG B:CYS431 2.3 81.8 1.0 SG B:CYS434 2.4 86.0 1.0 SG B:CYS455 2.5 67.4 1.0 CB B:CYS431 2.7 76.6 1.0 CB B:CYS452 3.4 71.8 1.0 OG1 B:THR436 3.6 49.4 1.0 CB B:THR436 3.8 52.4 1.0 CB B:CYS434 3.8 81.6 1.0 N B:CYS434 3.8 79.7 1.0 CB B:CYS455 3.9 65.3 1.0 N B:THR436 4.1 63.4 1.0 CA B:CYS431 4.1 76.6 1.0 N B:CYS455 4.2 64.5 1.0 CA B:CYS434 4.2 78.7 1.0 N B:ARG435 4.5 76.7 1.0 C B:CYS434 4.5 75.0 1.0 CA B:THR436 4.6 56.7 1.0 CA B:CYS455 4.6 65.9 1.0 C B:CYS431 4.7 79.6 1.0 CB B:LEU454 4.8 60.0 1.0 CA B:CYS452 4.8 71.0 1.0 CB B:SER433 4.9 82.2 1.0 O B:CYS431 4.9 78.2 1.0 N B:CYS431 4.9 71.5 1.0 CG2 B:THR436 5.0 49.5 1.0 N B:SER433 5.0 83.1 1.0 C B:SER433 5.0 81.0 1.0

W.Ma, E.Goldberg, J.Goldberg. Er Retention Is Imposed By Copii Protein Sorting and Attenuated By 4-Phenylbutyrate. Elife V. 6 2017.
ISSN: ESSN 2050-084X
PubMed: 28594326
DOI: 10.7554/ELIFE.26624