Zinc in PDB 5ub9: Catalytic Core Domain of Adenosine Triphosphate Phosphoribosyltransferase From Campylobacter Jejuni

All present enzymatic activity of Catalytic Core Domain of Adenosine Triphosphate Phosphoribosyltransferase From Campylobacter Jejuni:
2.4.2.17;

The structure of Catalytic Core Domain of Adenosine Triphosphate Phosphoribosyltransferase From Campylobacter Jejuni, PDB code: 5ub9 was solved by G.Mittelstaedt, W.Jiao, E.K.Livingstone, E.J.Parker, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.96 / 1.90
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	65.697, 79.926, 91.006, 90.00, 90.00, 90.00
R / Rfree (%)	19.3 / 24.3

The structure of Catalytic Core Domain of Adenosine Triphosphate Phosphoribosyltransferase From Campylobacter Jejuni also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Zinc atom in the Catalytic Core Domain of Adenosine Triphosphate Phosphoribosyltransferase From Campylobacter Jejuni (pdb code 5ub9). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Catalytic Core Domain of Adenosine Triphosphate Phosphoribosyltransferase From Campylobacter Jejuni, PDB code: 5ub9:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Catalytic Core Domain of Adenosine Triphosphate Phosphoribosyltransferase From Campylobacter Jejuni


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Catalytic Core Domain of Adenosine Triphosphate Phosphoribosyltransferase From Campylobacter Jejuni within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:17.7 occ:0.60 NE2 A:HIS35 2.1 31.7 1.0 ND1 A:HIS33 2.1 32.9 1.0 CL A:CL305 2.1 30.0 1.0 CE1 A:HIS33 3.0 33.6 1.0 CE1 A:HIS35 3.0 32.3 1.0 CD2 A:HIS35 3.1 33.0 1.0 CG A:HIS33 3.1 32.5 1.0 CB A:HIS33 3.4 31.8 1.0 NE2 A:HIS33 4.1 33.0 1.0 ND1 A:HIS35 4.1 31.7 1.0 CD2 A:HIS33 4.2 31.7 1.0 CG A:HIS35 4.2 33.1 1.0 O A:HOH495 4.9 32.3 1.0 CA A:HIS33 5.0 31.1 1.0

Zinc binding site 2 out of 2 in the Catalytic Core Domain of Adenosine Triphosphate Phosphoribosyltransferase From Campylobacter Jejuni


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Catalytic Core Domain of Adenosine Triphosphate Phosphoribosyltransferase From Campylobacter Jejuni within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn301 b:28.5 occ:1.00 NE2 B:HIS35 2.0 33.8 1.0 ND1 B:HIS33 2.2 29.9 1.0 CE1 B:HIS35 2.7 35.5 1.0 CG B:HIS33 3.1 28.9 1.0 CE1 B:HIS33 3.1 29.1 1.0 CD2 B:HIS35 3.2 33.6 1.0 CB B:HIS33 3.4 27.9 1.0 ND1 B:HIS35 3.9 34.5 1.0 CG B:HIS35 4.2 32.2 1.0 NE2 B:HIS33 4.2 30.4 1.0 CD2 B:HIS33 4.2 29.6 1.0 CA B:HIS33 4.9 27.5 1.0

G.Mittelstadt, W.Jiao, E.K.Livingstone, G.J.Moggre, A.R.Nazmi, E.J.Parker. A Dimeric Catalytic Core Relates the Short and Long Forms of Atp-Phosphoribosyltransferase. Biochem. J. V. 475 247 2018.
ISSN: ESSN 1470-8728
PubMed: 29208762
DOI: 10.1042/BCJ20170762