Zinc in PDB 5tbn: Solution uc(Nmr) Structure of PHF20 Phd Domain in Complex with A Histone H3K4ME2 Peptide

The binding sites of Zinc atom in the Solution uc(Nmr) Structure of PHF20 Phd Domain in Complex with A Histone H3K4ME2 Peptide (pdb code 5tbn). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Solution uc(Nmr) Structure of PHF20 Phd Domain in Complex with A Histone H3K4ME2 Peptide, PDB code: 5tbn:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Solution uc(Nmr) Structure of PHF20 Phd Domain in Complex with A Histone H3K4ME2 Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Solution uc(Nmr) Structure of PHF20 Phd Domain in Complex with A Histone H3K4ME2 Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn800 b:0.0 occ:1.00 SG A:CYS51 2.3 0.0 1.0 SG A:CYS23 2.3 0.0 1.0 SG A:CYS26 2.4 0.0 1.0 SG A:CYS48 2.4 0.0 1.0 H A:CYS26 2.9 0.0 1.0 HB2 A:CYS51 3.2 0.0 1.0 HB3 A:GLU25 3.2 0.0 1.0 H A:CYS48 3.3 0.0 1.0 CB A:CYS23 3.4 0.0 1.0 HB3 A:CYS48 3.4 0.0 1.0 CB A:CYS51 3.4 0.0 1.0 HB3 A:CYS23 3.4 0.0 1.0 HB3 A:CYS26 3.4 0.0 1.0 CB A:CYS26 3.4 0.0 1.0 HB2 A:CYS23 3.5 0.0 1.0 CB A:CYS48 3.5 0.0 1.0 HG12 A:VAL50 3.5 0.0 1.0 H A:CYS51 3.6 0.0 1.0 SG A:CYS28 3.6 0.0 1.0 HG A:CYS28 3.7 0.0 1.0 N A:CYS26 3.7 0.0 1.0 N A:CYS51 4.0 0.0 1.0 CA A:CYS26 4.1 0.0 1.0 N A:CYS48 4.2 0.0 1.0 HB3 A:CYS51 4.2 0.0 1.0 HB A:VAL50 4.3 0.0 1.0 H A:CYS28 4.3 0.0 1.0 H A:GLU25 4.3 0.0 1.0 CB A:GLU25 4.3 0.0 1.0 HB2 A:CYS48 4.3 0.0 1.0 CA A:CYS51 4.3 0.0 1.0 CA A:CYS48 4.3 0.0 1.0 HB2 A:CYS26 4.4 0.0 1.0 O A:CYS48 4.4 0.0 1.0 CG1 A:VAL50 4.5 0.0 1.0 HG3 A:GLU25 4.5 0.0 1.0 HG11 A:VAL50 4.7 0.0 1.0 H A:GLN27 4.7 0.0 1.0 C A:GLU25 4.7 0.0 1.0 C A:VAL50 4.8 0.0 1.0 C A:CYS48 4.8 0.0 1.0 C A:CYS26 4.8 0.0 1.0 CA A:CYS23 4.8 0.0 1.0 HA A:CYS51 4.8 0.0 1.0 CB A:VAL50 4.8 0.0 1.0 HB2 A:GLU25 4.8 0.0 1.0 HA A:THR47 4.9 0.0 1.0 CA A:GLU25 4.9 0.0 1.0 CG A:GLU25 4.9 0.0 1.0 N A:GLU25 4.9 0.0 1.0

Zinc binding site 2 out of 2 in the Solution uc(Nmr) Structure of PHF20 Phd Domain in Complex with A Histone H3K4ME2 Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Solution uc(Nmr) Structure of PHF20 Phd Domain in Complex with A Histone H3K4ME2 Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn801 b:0.0 occ:1.00 ND1 A:HIS31 2.1 0.0 1.0 SG A:CYS34 2.3 0.0 1.0 SG A:CYS11 2.3 0.0 1.0 SG A:CYS9 2.3 0.0 1.0 HB2 A:CYS11 2.8 0.0 1.0 HB2 A:HIS31 3.0 0.0 1.0 CE1 A:HIS31 3.1 0.0 1.0 CG A:HIS31 3.1 0.0 1.0 CB A:CYS34 3.3 0.0 1.0 CB A:CYS11 3.3 0.0 1.0 HB2 A:CYS34 3.3 0.0 1.0 HD12 A:ILE10 3.3 0.0 1.0 HB3 A:CYS34 3.3 0.0 1.0 HE1 A:HIS31 3.3 0.0 1.0 HB3 A:CYS9 3.5 0.0 1.0 CB A:CYS9 3.5 0.0 1.0 CB A:HIS31 3.6 0.0 1.0 H A:HIS31 3.7 0.0 1.0 H A:CYS11 3.8 0.0 1.0 HB2 A:CYS9 3.8 0.0 1.0 HB3 A:CYS11 3.9 0.0 1.0 NE2 A:HIS31 4.2 0.0 1.0 CD2 A:HIS31 4.2 0.0 1.0 HD11 A:ILE10 4.2 0.0 1.0 CD1 A:ILE10 4.2 0.0 1.0 HB3 A:HIS31 4.3 0.0 1.0 N A:CYS11 4.4 0.0 1.0 HG13 A:ILE10 4.4 0.0 1.0 HG12 A:VAL13 4.4 0.0 1.0 CA A:CYS11 4.4 0.0 1.0 N A:HIS31 4.5 0.0 1.0 CA A:HIS31 4.6 0.0 1.0 HD21 A:ASN17 4.7 0.0 1.0 CA A:CYS34 4.7 0.0 1.0 O A:HIS31 4.8 0.0 1.0 HA A:CYS11 4.9 0.0 1.0 CA A:CYS9 4.9 0.0 1.0 H A:CYS34 4.9 0.0 1.0 H A:ILE10 4.9 0.0 1.0 HA A:CYS34 4.9 0.0 1.0 CG1 A:ILE10 4.9 0.0 1.0

B.J.Klein, X.Wang, G.Cui, C.Yuan, M.V.Botuyan, K.Lin, Y.Lu, X.Wang, Y.Zhao, C.J.Bruns, G.Mer, X.Shi, T.G.Kutateladze. PHF20 Readers Link Methylation of Histone H3K4 and P53 with H4K16 Acetylation. Cell Rep V. 17 1158 2016.
ISSN: ESSN 2211-1247
PubMed: 27760318
DOI: 10.1016/J.CELREP.2016.09.056